Acrodermatitis Enteropathica
General
Disease Name
Acrodermatitis Enteropathica
OMIA
593
Gene Name
unknown
Mutation
unpublished
Test Type
Genetic Disease/Disorder
Details
Puppies Affected by Lethal Acrodermatits (LAD) have characteristic skin lesions and fail to thrive. These lesion consist of Erythema and adherent scales, primary on the feet, elbows, hocks and muzzle. Hyperkeratosis of the foot pads also occurs. Dogs with LAD are also immunodeficient, so frequently suffering from skin infections such as Malassezia or Candida. Puppies suffering from this condition have a greatly reduced lifespan either due to infections or they are euthanized when the condition becomes very severe and painful. (From the AHT)
Published
No test/mutation publication information.
Published 2
2007 Grider, A., Mouat, M.F., Mauldin, E.A., Casal, M.L. : Analysis of the liver soluble proteome from bull terriers affected with inherited lethal acrodermatitis. Mol Genet Metab 92:249-57, 2007. Pubmed reference: 17693109. DOI: 10.1016/j.ymgme.2007.07.003.
Body/System/Process
Skin
OMIA Url
Inheritance
AR
Breed Specific Info
Researched Breeds
Bull Terrier