Colorectal Hamartomatous Polyposis and Ganglioneuromatosis
Breed: East Siberian Laika
General
Disease Name
Colorectal Hamartomatous Polyposis and Ganglioneuromatosis
OMIA
1515
Gene Name
PTEN
Mutation
Duplication of PTEN
Test Type
Genetic Disease/Disorder
Details
Reported disease indicators include: hematochezia, tenesmus, and rectal prolapse. Also reported that the colorectal segment had diffuse mucosal and submucosal thickening with multiple polypoid nodules. (Bemelmans, et al., 2011)
Details 2
Reported disease indicators include: hematochezia, tenesmus, and rectal prolapse. Also reported that the colorectal segment had diffuse mucosal and submucosal thickening with multiple polypoid nodules. (Bemelmans, et al., 2011)
Published
Bemelmans, I., Küry, S., Albaric, O., Hordeaux, J., Bertrand, L., Nguyen, F., Abadie, J. : Colorectal hamartomatous polyposis and ganglioneuromatosis in a dog. Vet Pathol 48:1012-5, 2011. Pubmed reference: 20952721. DOI: 10.1177/0300985810384411.
Body/System/Process
Gastrointestinal
OMIA Url
Inheritance
AR
Breed Specific Info
Researched Breeds
Great Dane