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  1. Breed Relevance Ratings (BRR) are a way to assess the relevance of a specific test for a specific breed, based on the currently best-known information on the research and development of a test - but genetic tests are not limited to pedigree breeds. Genetic tests are used for a variety of reasons on all dogs, and understanding the relevance is important for any purpose-bred dog or breeding program, as well as individual dogs. BRR’s are estimated for all dogs, and where the research is not available for a specific breed or type, we have processes to provide transparent information about test rel
  2. HGTD This Week: NEW Inclusive breed-specific test listings on HGTD In our continued effort to improve HGTD, we have made major changes to our breed-specific genetic test listings. We’ve added a number of new features and information to help owners, breeders, and canine health professionals make the most of the breed-specific test listings. See the updated article: HGTD - What is a Breed Relevance Rating? for more details. NEW Test type descriptions Breed-specific tests are now listed under 4 different categories of tests: Genetic Disease/Disorder, Other Genetic Traits, D
  3. In This Issue: News & Highlights An Update on IPFD's Call for Respectful Dialogue, Collaboration, and Collective Actions Make a Donation Stay Informed!
  4. In This Issue: News & Highlights Reframing Current Challenges Around Pedigree Dogs A Call for Respectful Dialogue, Collaboration, and Collective Actions Make a Donation Stay Informed!
  5. IPFD's genetic testing resources are mentioned in media stories on international research that has documented the molecular basis of the Australian Labradoodle. Their main conclusion is that animals in the Australian Labradoodle breed registry are mostly poodle, and not a 50-50 split as might have been expected.
  6. This year has been challenging for all organizations globally. However, IPFD has fared well. We have always been a ‘virtual’-based operation, with all consultants working from home. Building on our 2019 Annual Report: A Growing Voice, this milestones document is meant to update our Partners and Sponsors on our activities in 2020. – Dr. Brenda Bonnett, CEO (click to download/share as a PDF): IPFD Milestones December 2020.pdf Message from the Canadian Kennel Club: “CKC’s membership in the International Partnership for Dogs, and participation in the biennial D
  7. Vets – what can HGTD do for you? Genetic testing is part of our dog's lives Just as genetic testing has become normalized in the human world, thanks to popular direct to consumer products like 23 and Me, or Ancestry.com, so it has in the veterinary world. While perhaps once the preserve of specialist dog breeders, it is increasingly common for vets in practice to have questions from clients about DNA testing. While covering the basics of testing and inheritance is part of many veterinary educations, it is unreasonable to expect anyone to have knowledge of the 300+ different genetic
  8. HGTD This Week, 7 Aug 2020: Canine Crime Scene Investigators When we think about genetic testing, we often focus on how it can be a tool to improve health and welfare - generally centered around breeding for health or finding more about the health or potential health risks for an individual dog. Knowing about health risks that are especially relevant to specific breeds or dog types makes testing even more powerful in helping reduce risks of disease or undesirable traits (see Breed Relevancy Ratings). Most commonly, genetic screening and diagnostic testing focuses on: disease tests, breed e
  9. The Harmonization of Genetic Testing for Dogs (HGTD) project work includes harmonizing genetic test information across many different boundaries. That can be as simple as adding consistency to nomenclature from around the world, or as challenging as cataloging test information and research from dozens of different international sources. With so much variation in how tests are developed, and how they are released to the public, a big part of my work is ensuring that phene names we publish on HGTD are consistent, accurate, and representative of whatever genetic test a person is seeking out.
  10. In This Issue: News & Highlights Actions Around Brachycephalic Dogs: Reports, Research, and Legislative Developments in Several Countries Make a Donation Stay Informed!
  11. The continued review of breed-specific tests for assigning relevance ratings, and ongoing discussions with genetic experts has led to a refinement of the breed relevance ratings (please see: BRR) . To better accommodate the spectrum of genetic test validation, we’ve added a new orange BRR. The orange BRR indicates where all current available evidence has been reviewed, but the relevance is inconclusive. It could be that a mutation is detectable in a specific breed, but that there is no evidence that this correlates with clinical development of the disease/phene. It could also be that the
  12. HGTD, and IPFD, were thrilled to be able to send our very best wishes and acknowledgements to Prof Frank Nicholas, on the 25th Anniversary of the Online Mendelian Inheritance in Animals (OMIA) resource. (see Brenda's Blog) Collaboration with, and integration of OMIA's information is vital for a lot of what HGTD is able to do - and fundamental to animal genetics researchers the world over. OMIA is a catalogue/compendium of inherited disorders, other (single-locus) traits, and genes in 251 animal species. OMIA is a great example of collaboration in action - authored by Professor Frank Nicholas o
  13. Congratulations to the University of Sydney and OMIA - the Online Mendelian Inheritance in Animals database. 25 years old 25 May 2020. Check out the celebration webpage here. This amazing resource underpins research and education on genetics in many species and has been a key support for advancement in the world of dog genetics and genomics. The development and maintenance of this fantastic database is due to the input and support of many academics, researchers, and others, many of whom volunteer their expertise and time. But it would not have existed or been maintained with
  14. HGTD Update: 12 May 2020 Since the last blog, we’ve had additional expert review of many Breed Relevance Ratings (BRRs) – particular in commonly tested eye conditions, and ataxias. As we are growing our expert out-reach for input into BRRs, we are pleased to note that there is consensus between experts self-reviewing their tests as well as peer-reviewing each other. This adds reassurance to us that the current BRR estimation of combining what we can learn from research publications, phene discoverer’s expert opinions, and informal peer-review between geneticists, is working. So far, we ha
  15. "The IPFD's signature event, the International Dog Health Workshops (IDHW) bring together decision makers from kennel and breed clubs, professional, regulatory, national and regional, welfare and other organisations that are stakeholders in dog health, well-being and welfare and human-dog interactions under the tagline 'From Information and Collaboration to Action'." We are excited to report the online publication of the report on the 4th International Dog Health Workshop. We are particularly excited to report that actions prioritized at that meeting are underway and outcomes are bein
  16. We get questions about how we ensure the quality of the information available on HGTD. It can actually be very challenging, and we rely on having good processes, and collaboration when developing content. To meet the IPFD principle of transparency, we are starting a series of blogs to describe how we manage this resource. We hope to then provide a regular news feed on HGTD developments and changes, to give you all an insight into this work. To get started, here is a little insight into running and maintaining HGTD. How do new genetic test providers (GTPs) join? GTPs reach HGTD
  17. Is COVID-time the Right Time to Kon Mari Your Genetic Testing Plans? a blog by Aimee Llewellyn-Zaidi, MSc; Project Director of the IPFD Harmonization of Genetic Testing for Dogs (HGTD) initiative. “People around the world have been drawn to this philosophy not only due to its effectiveness, but also because it places great importance on being mindful, introspective and forward-looking.” -Marie Kondo, Founder of the Kon Mari method. If you’ve already, like so many of us, used the Kon Mari de-cluttering method of “sparking joy” and being “mindful, introspective, and forwar
  18. The HGTD arose from discussions at the IPFD International Dog Health Workshops (IDHWs); it is a proud achievement, exemplifying the IDHW tagline: Information – Collaboration – Action! In 2019, the HGTD project could be summarized in one word: Growing. We’ve consistently grown our list of genetic test providers (GTPs). Participating GTPs have provided information on their accreditation, expertise, and practices – all of which helps individuals find a GTP that has the quality measures most important to them. The generic phenes database provided a centralized resource for researchers,
  19. AUTHOR: HELLE FRIIS PROSCHOWSKY, DVM, PH.D., SPECIAL CONSULTANT, THE DANISH KENNEL CLUB (DKC) See: https://www.dachshund-ivdd.uk/what-is-ivdd/danish-ivdd-paper-2019/ PDF version: https://www.dachshund-ivdd.uk/app/download/11009159/Herniated+discs+HFP+2019+v4.pdf IVDD is explored in this concise presentation which was originally published in the March 2019 issue of the Danish Kennel Club magazine (HUNDEN). Translated version by Frøydis Hardeng and Ian Seath..
  20. HGTD - What is a Breed Relevance Rating? To better support dog owners, the veterinary community, and dog health advisors, in 2020 we introduced Breed Relevance Ratings in the HGTD. Below you will find an explanation of what the Breed Relevance Rating (BRR) is and why it is important. A work in progress... the BRR is a dynamic index that may change as new information becomes available. To summarize the HGTD database relevance rating indicates the level of available evidence supporting the application of a specific genetic test for a specific breed/type.Currently, the relevanc
  21. What a great weekend of education - with the Canadian Kennel Club and about 170 participants, including breeders with a range of experience from over 40 years to novices. Speakers Dr. Kari Ekenstedt, a geneticist from Purdue University in Indiana and IPFD CEO Dr. Brenda Bonnett covered 'everything you need to know to understand genetic testing' in a clear, concise and entertaining series of talks. Interactive discussions with the many knowledgeable, committed attendees were interesting and thought-provoking. Read more here. Download the schedule here: CKC Seminar Schedule Final.pdf
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