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Theme attended at 3rd IDHW in Paris

Found 10 results

  1. Version 1.0.0

    1 download

    ON THE ORIGINS OF BREED TYPES BY MEANS OF HUMAN ACTION Slides from Peter Friedrich's plenary talk from the 4th IDHW, Windsor, 31 May 2019 Also see: Friedrich, Peter, 2018, Questionable Phenotypic Traits in the Rottweiler - which offers information on valuable breed traits, comments on the "Redesigned Rottweilers with extreme characteristics..." i.e. the impacts of trendiness supported by media and human motivations to possess special, extravagant and innovative dogs."
  2. Purdue University News - Press release - Your dog might be hiding its true colors From the Press release... " New research from Purdue University’s College of Veterinary Medicine shows that some breeds of dogs have hidden coat colors – and in some cases, other traits – that have been lurking all along. Example: There are around 18 recognized breeds of dogs that have the genetic potential to be born without a tail – such as the popular Australian Shepherd (shown in photo). But the data shows that up to 48 of the breeds analyzed possess the tailless gene variant, usually at a very low frequency." Wisdom Health - Press release - First-of-its-kind study reveals genetic traits determining coat colors and physical appearance in over 200 dog breeds November 2019 From the Press release... "As our study demonstrates, purebred dogs have so much more than meets the eye - literally. The information provided by a WISDOM PANEL dog DNA test can help us better understand the hidden elements of dog genetics," said Dr. Angela Hughes DVM PhD, veterinarian and canine genetics expert at Wisdom Health. "While our study focused primarily on purebred populations, these hidden traits can also have ramifications for mixed breed dogs. When unexpected or hidden traits are passed to mixed breed dogs from their purebred ancestors, it further complicates the already difficult task of visual breed identification making DNA tests the only reliable method of determining breed ancestry." Read the study... True Colors: Commercially-acquired morphological genotypes reveal hidden allele variation among dog breeds, informing both trait ancestry and breed potential Comment: Extracted content of interest to dog breeders & breed managers... See S3 Table. Unfavorable or “fault” phenotypes possible by breed and breed registry. "Breeds genotyped to have alleles that would produce phenotypes considered as a “fault” by either the American Kennel Club (AKC), Fédération Cynologique Internationale (FCI), United Kennel Club (UKC), or The Kennel Club of the UK (KC). The level of tolerance within each breed registry is designated as either not allowed (N), not preferred (n.p.), allowed (Y), or ambiguously worded (amb.). A breed not recognized by a given organization is indicated with a dash (-). Inheritance of the fault-causing allele is designated as dominant (D), recessive (R), or compound heterozygote (CH). Breed name abbreviations are as listed in S1 Table. Probabilities for producing the non-standard phenotype were calculated assuming random mating within the breed, and account for multi-gene inheritance, expression, and epistatic effects." https://doi.org/10.1371/journal.pone.0223995.s005 " Much recent emphasis has been placed on the importance of genetic diversity within breeds [69–76]. With the conservation of diversity in mind, breeders and breed organizations must weigh the relative value of breed standard conformity with preservation of genetic diversity. The existence of unfavorable, though arguably benign pigmentation or morphological variations, has here been quantified and can be addressed by applied genetic screening to reduce the carrier frequency of breeding stock, or by reassessing breed standards to broaden the acceptance of preexisting variation. Likewise, though our analyses have indicated that production of disallowed phenotypes is generally quite low, the occurrence of an undesirable pigmentation trait should not necessarily exclude a dog from purebred status if that variant has been detected in the appropriate population. As a recent example, effective 1 January 2019, the Great Dane Club of America revised their breed standard to allow merle coloring on a black base. Canine genetic research has clarified that the presence of the merle allele is required for the Harlequin phenotype [14]; since this relationship was previously unclear, the breed had not allowed merle (without the Harlequin modifier) until this change. These revisions demonstrate the purebred dog community recognizing and willingly implementing the findings from canine genetic research. The present work will guide similar decision-making by breed clubs regarding definition of acceptable breed colors. "
  3. Jerold S Bell DVM (jerold.bell@tufts.edu) Cummings School of Veterinary Medicine at Tufts University presented this article at the 2019 AKC Canine Health Foundation National Parent Club Canine Health Conference. The article has been reprinted here with the written permission of the author.
  4. Dave St. Louis

    Breeds

    Here you will find an overview of breed resources on DogWellNet.com. This is not a comprehensive listing - it is a starting point for finding relevant resources. Please visit the various areas of the site using the purple navigation bar and/or the Search function.
  5. 2019 Lewis TW, Mellersh CS. Changes in mutation frequency of eight Mendelian inherited disorders in eight pedigree dog populations following introduction of a commercial DNA test. Plos One, https://doi.org/10.1371/journal.pone.0209864 DNA Testing - General Subject: DNA Testing Type: Research Journal/Source: peer-reviewed research publication Authors/Researchers: University, Kennel Club (IPFD Partners); HGTD Participants Recommended For: Veterinarians, Owners/Breeders This study is one of the very few to investigate the impact of DNA testing on changing a dog population's disease risk. The research looked at determining changes in frequency of disease causing mutations (how common a mutant gene is in a population) as a result of breeding-pair selection based on DNA test results. The results indicated that there has been an overall decline in disease causing mutations in the 8 diseases in 8 breeds investigated. While the paper recognises that there can be variations in how quickly a disease is reduced or eliminated (such as breed population size), it concluded that where dog breeders appear to incorporate DNA test results as part of breeding plans, there is success in decreasing the frequency of mutation. The study looked at: prcd-PRA in Labrador Retriever and Cocker Spaniel, HC in Staffordshire Bull Terriers, EIC in Labrador Retriever, PLL in Mini-Bull Terrier, EF and DE/CC in Cavalier King Charles Spaniel, PRA rcd-4 in Gordon, and Irish Setter, and spinocerebellar ataxia in Parson Russell Terrier. Within the UK at least, this represents a spectrum of large and small breeds, and generally "known" diseases within the breeds. 2019 Lewis TW, Mellersh CS. Changes in mutation frequency of eight Mendelian inherited disorders in eight pedigree dog populations following introduction of a commercial DNA test. Plos One, https://doi.org/10.1371/journal.pone.0209864 See also: Nearly 20 Years of DNA Testing – What Can We Learn? : IPFD CEO's blog post with discussion of wider implications of the study's approach and findings; based on Ian Seath's commentary (Dog-ED: Social Enterprise) with a breeder/health council perspective on the article above. IPFD Harmonization of Genetic Testing (HGTD) and search on the mentioned diseases for more information on the the condition, phenes, tests and more.
  6. Version 1.0.0

    13 downloads

    This overview offers discussion on definitions of "Breed"... excerpts... Pros and cons of the definitions we use today. Is it possible to have closed studbooks forever? Genetic diversity – why is that important? Benefits/risks/need to include the expanding population of ‘consumer-defined’ crosses in discussions and education? Two different scenarios Cross breeding projects Open studbooks
  7. Version 1.0.0

    8 downloads

    A presentation at the 4th International Dog Health Workshop by Helena Skarp that provides an overview of the concept of breed including a discussion of 'breed' in relation to selection, conservation, preservation, genetic diversity and health.
  8. Version 1.0.0

    7 downloads

    A presentation given by Gregoire Leroy at the 4th International Dog Health Workshop that explores the concept of breeds and their management. "Breed is a central concept in dog breeding... "
  9. Several recent articles have raised concerns about the quality of canine genetic testing. There is concern about the quality measures, standards and practices of genetic test providers (GTPs), but there are also factors related to test discovery, validation and application that may limit our ability to get the most out of genetic testing. Confusion, lack of transparency, absence of needed information on many levels, and incomplete understanding of the situations, individuals and breeds where testing is most useful are among the challenges. This article is in response to numerous queries and discussions on what is needed to improve the situation.
  10. The book, Standards, Santé et Génétique chez le Chien / Standards, Health and Genetics in the Dog was created by the Société Centrale Canine (SCC) in collaboration with the Fédération Cynophile Internationale (F.C.I.) and the Swedish Kennel Club (SKK). Under the direction of Claude Guintard and Grégoire Leroy, the publication was presented as a tribute to Mrs. René Sporre-Willes and Mr. Raymond Triquet, longstanding chairs of the F.C.I.'s the Standards Commission, at the Third IPFD Dog Health Workshop held in Paris from April 21 to 23, 2017. Standards, Santé et Génétique chez le Chien / Standards, Health and Genetics in the Dog presents information from the world of dogs which can be applied in service to canine and human health and well-being. This work includes contributions by veterinarians, researchers, and dog-theorists who offer insights into the development of breed standards as well as the incredible advances in molecular genetics. We at DogWellNet are delighted to be able to present the content from this book's 396 pages which includes 20 texts in English and in French distributed in two large chapters. The book's Table of Contents (TOC-Standards, Santé et Génétique chez le Chien-Standards, Health and Genetics in Dogs) is available to DWN guests as well as DWN members. DWN members will have access to all of the book's texts available in DWN's Downloads section. Over the coming year we will feature texts from the book in DWN articles which will be accessible to DWN's members as well as guests. We would like to thank the book's producers and authors for their exceptional knowledge, extraordinary insights and for their willingness to share their expertise with people who are a part of the international dog community.
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