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Found 13 results

  1. 2019 Lewis TW, Mellersh CS. Changes in mutation frequency of eight Mendelian inherited disorders in eight pedigree dog populations following introduction of a commercial DNA test. Plos One, https://doi.org/10.1371/journal.pone.0209864 DNA Testing - General Subject: DNA Testing Type: Research Journal/Source: peer-reviewed research publication Authors/Researchers: University, Kennel Club (IPFD Partners); HGTD Participants Recommended For: Veterinarians, Owners/Breeders This study is one of the very few to investigate the impact of DNA testing on changing a dog population's disease risk. The research looked at determining changes in frequency of disease causing mutations (how common a mutant gene is in a population) as a result of breeding-pair selection based on DNA test results. The results indicated that there has been an overall decline in disease causing mutations in the 8 diseases in 8 breeds investigated. While the paper recognises that there can be variations in how quickly a disease is reduced or eliminated (such as breed population size), it concluded that where dog breeders appear to incorporate DNA test results as part of breeding plans, there is success in decreasing the frequency of mutation. The study looked at: prcd-PRA in Labrador Retriever and Cocker Spaniel, HC in Staffordshire Bull Terriers, EIC in Labrador Retriever, PLL in Mini-Bull Terrier, EF and DE/CC in Cavalier King Charles Spaniel, PRA rcd-4 in Gordon, and Irish Setter, and spinocerebellar ataxia in Parson Russell Terrier. Within the UK at least, this represents a spectrum of large and small breeds, and generally "known" diseases within the breeds. 2019 Lewis TW, Mellersh CS. Changes in mutation frequency of eight Mendelian inherited disorders in eight pedigree dog populations following introduction of a commercial DNA test. Plos One, https://doi.org/10.1371/journal.pone.0209864 See also: Nearly 20 Years of DNA Testing – What Can We Learn? : IPFD CEO's blog post with discussion of wider implications of the study's approach and findings; based on Ian Seath's commentary (Dog-ED: Social Enterprise) with a breeder/health council perspective on the article above. IPFD Harmonization of Genetic Testing (HGTD) and search on the mentioned diseases for more information on the the condition, phenes, tests and more.
  2. The Kennel Club recognizes DNA tests and schemes in conjunction with breed clubs and laboratories, some of which are recorded by the Kennel Club on the registration database and are available to view via the online tool Health Test Results Finder.
  3. Version updates - Spring 2018

    688 downloads

    The Kennel Club recognises DNA tests and schemes in conjunction with breed clubs and laboratories, some of which are recorded by the Kennel Club on the registration database and are available to view via the online tool Health Test Results Finder. The list below displays the DNA tests available for each breed along with an indication as to whether the test is part of the Assured Breeder Scheme (recommended or required) and whether it is recorded on the Kennel Club registration database. DNA tests are not yet available for every breed. Please see current information including updated versions of DNA tests at... https://www.thekennelclub.org.uk/health/for-breeders/dna-testing-simple-inherited-disorders/worldwide-dna-tests/. External links: Afghan Hound - Bull Terrier (miniature) Cairn Terrier - Dogue de Bordeaux English Setter - Greyhound Havanese - Kooikerhondje Lagotto Romagnolo - Otterhound Papillon - Pyrenean sheepdog Retriever (Chespaeake Bay) - Russian black terrier Saluki - Swedish Vallund Tibetan Spaniel - Yorkshire Terrier Also see: BREED SPECIFIC REQUIREMENTS AND RECOMMENDATIONS INCLUDING HEALTH SCREENING -- https://www.thekennelclub.org.uk/media/9846/abs_breed_specific_requirements_and_recommendations_web.pdf Updated September 2018 This list is subject to change. The most up-to-date version will be found at: www.assuredbreeders.org.uk
  4. - October 31, 2018 - News from the Société Centrale Canine - LOF Select ♦ Article - UPDATED: 12-5-2018 ♦ Congratulations and Thanks to IPFD Partners, SCC, the French Kennel Club, for recognizing the importance of HGTD in their steps to protect the quality of their pedigree and health database. Stay tuned for more information on their approach and plans... In the meantime see news just in from the French Kennel Club... And see updated information from the SCC's Health and Genetic Resources Project Manager, Fleur Marie Missant, on this change of the rules for registering data in the SCC database.
  5. Here we offer answers to some frequently asked questions about the Harmonization of Genetic Testing for Dogs.
  6. The great juggling act...Ask any long time dog breeder and they'll tell you, exploring the subject of dog breeding and looking at how to define 'best practices' that lead to production of healthy, functional dogs is getting more complicated by the day! A COMPLEX BALANCE: What are You Measuring? How do you define and verify successes or failures? Health status (current or long-term) is but one part of a breeder's evaluation of a dog's suitability for breeding. Assessing a dog's health and any other quality or characteristic goes hand-in-hand with the breeder's goals and reasons for breeding/keeping dogs. A breeder's evaluation of the dog's conformation/structure, breed type, temperament, personality, working ability and serviceability is combined with health considerations at the time of breeding and beyond. Juggling all the different 'balls' of whether a dog is to to be included or excluded from a breeding program, a pairing is likely to produce quality offspring or developing a workable breeding strategy for an entire breed is an extremely difficult task. Screening for hips, elbows, heart and eye examinations by veterinarians, expert evaluators, and a myriad of schemes developed to govern those types of non-dna evaluations have long been considered by health-conscious breeders as essential components of quality breeding programs. Enter the explosion of research on DNA and the dog genome - scientists are in the process of examining the genetic components of everything - health conditions and diseases, predispositions to manifest diseases, physical characteristics, longevity, genetic diversity, behaviours - in people, dogs and other species. DNA tests and direct to consumer sales of DNA tests has opened up a whole new world of 'evaluation tools' for dog breeders. Understanding genetic testing and applying results of tests to breeding decisions and management of individual dogs and breeds is clearly no simple matter. The science is relatively new - but its effects are already widespread - for the better in some cases - but challenges exist. For insights... Check out Finnish Kennel club Breeding Experts, Taina Nygård and Katariina Mäki's writeup, Gene tests for consumer advice
  7. Search for a Genetic Test provider / Lab by country. Find out general information on the lab (website, address, phone), contact information, quality assurance indicators and genetic tests offered. Go to the HGTD Search by Lab / Test Provider.
  8. The search function offered here allows you to enter terms used to describe heritable diseases for which DNA tests are currently available. Breed-specific DNA tests and/or DNA tests applicable to all breeds are available in the HGTD database. Go to the HGTD Search by Test / Disease.
  9. HGTD - A quick look at the Search by Breed functionality. Go to the Harmonization of Genetic testing Search by Breed
  10. A tool to help dog owners, breeders and veterinarians...the HGTD is an online searchable database providing information on genetic tests available for dog breeds, information on the tests themselves and quality control measures used by genetic test providers participating in the HGTD. Search out tests, diseases (phenes), and labs. Find resources for genetic counselling.
  11. VetVine Hub Uploaded on Dec 9, 2017 The increasing availability of genetic screening tests, DNA tests, and now multiplex test panels also requires an understanding of what the tests tell you.
  12. Author: Dr Frédéric MAISON Membre du Comité de la SCC Président de la Commission d'élevage de la SCC
  13. DNA testing and domestic dogs - Cathryn Mellersh Received: 9 August 2011 / Accepted: 15 October 2011 / Published online: 10 November 2011 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275738/#Sec5title (external) DNA Testing and Domestic Dogs (internal) (PDF) "This article does not attempt to discuss every test available. Rather it discusses some of the considerations that should be taken into account to successfully translate scientific findings into robust and useful tools for the lay dog breeder to use, and in so doing it uses a few representative examples of DNA tests that are currently available." A table of DNA tests by breed is available via this article at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275738/table/Tab1/ and the table is shown in the PDF.
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