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Showing results for tags 'population'.
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The Kennel Club: Breed Population Analyses
Ann Milligan posted a article in Population | Breed Level
A research study of the population genetics of all Kennel Club registered breeds... "Recognising the importance of managing the rate of inbreeding, the Kennel Club's Population analysis reports allow breeders to review the unique situation for each breed. If unchecked, inbreeding levels can rise in a breed, and although its effects may not initially be noticeable, this increase can have a significant impact on the health and welfare of future generations. The breed specific reports... provide a framework to shape discussions on the best ways to improve, or m-
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Understanding Mixed-Breed and Purebred Populations
Ann Milligan posted a article in HGTD Genetic Counselling
Understanding Mixed-Breed and Purebred Populations WSAVA's November 2020 edition of the Bulletin highlights the work of the WSAVA Hereditary Disease Committee (HDC). For Veterinarians, breed clubs, and breeders see: Understanding Mixed-Breed and Purebred Populations. "Keen to understand more about mixed-breed and purebred populations and how they relate to genetic disease in your patients? Watch this lecture given by WSAVA HDC Chair Dr Jerold Bell at the virtual 2020 AVMA Convention in August (2020)." -
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This exciting research paper is from a PhD project involving several of our IPFD Partners and collaborators. It is the first step towards being able to access the vast data sources of various kennel clubs and to combine data across countries. Published in the J Anim Breed Genet. 2017 Apr;134(2):152-161. doi: 10.1111/jbg.12242. Epub 2016 Nov 10. Merging pedigree databases to describe and compare mating practices and gene flow between pedigree dogs in France, Sweden and the UK S. Wang1,2,3, G. Leroy2,3, S. Malm4, T. Lewis5,6, E. Strandberg1 &
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Whole genome sequence, SNP chips and pedigree structure: Building demographic profiles in domestic dog breeds to optimize genetic trait mapping Authors: Dayna L. Dreger, Maud Rimbault1, Brian W. Davis1, Adrienne Bhatnagar1, Heidi G. Parker, Elaine A. Ostrander Key Words: population, homozygosity, canine, inbreeding SUMMARY STATEMENT "Successful application of whole genome sequencing and genome-wide association studies for identifying both loci and mutations in canines is influenced by breed structure and demography, motivating us to generate breed-specific strategies for canine-
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