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DogWellNet Digest: Issue #32 - 18 September 2020
Dave St. Louis posted a article in DogWellNet.com Digest
In This Issue: News & Highlights Actions Around Brachycephalic Dogs: Reports, Research, and Legislative Developments in Several Countries Make a Donation Stay Informed! -
Click on a link below or scroll down to view each section: HGTD In The News HGTD News From IPFD Initiative Background Key Partners and Leadership Sponsors Executive Summary Timeline HGTD In The News September 14, 2020 IPFD Mentioned in Articles on Australian Labradoodle DNA Study (The Guardian, The Conversation) September 13, 2019: HGTD Interview in Story from ABC 10 (Sacramento, CA) May 16, 2019: HGTD Gets Mention in Story from WGME CBS 13 (Portland, ME) March 8, 2019: USA Today article: DNA testing kits for dogs are super popular. But the testing has some veterinarians pushing standards February 11, 2019: The Associated Press (and various media) article: Dog DNA Testing Takes Off, and Generates Debate November 12, 2018: HGTD featured in The Atlantic: What Vets Think of ‘23andMe for Dogs’ October 3, 2018: IPFD submission responding to “Pet genomics medicine runs wild” published in Nature Visit our IPFD in the Media section for more published articles, commentaries, etc. from outside organizations that reference the HGTD or IPFD. Items in this section related to the HGTD specifically are also presented together in the article In the News: Harmonization of Genetic Testing for Dogs. HGTD News from IPFD December 19, 2018: Update on the Harmonization of Genetic Testing for Dogs (HGTD) Visit our IPFD News section for more news related to the HGTD and other IPFD news. HGTD Initiative Description The IPFD Harmonization of Dogs (HGTD) is a multi-stakeholder, collaborative effort to create an open access, sustainable online resource that: Catalogs information provided voluntarily from genetic test providers (GTPs) including information on their company and services, quality measures and expertise, tests offered and more. We are continually engaging more GTP participants. Has collated and assembled existing and new resources for genetic counselling and education; and provided the foundation for further developments. Will host expert panel reviews of genetic tests and their application. Plans to include a program for standardized proficiency testing and potentially peer review and audit. A related development, the Health Strategy Database for Dogs, will include a comprehensive list of conditions (potentially inherited) by breed, country and organization or group who has developed recommendations (i.e. Health Strategy Providers). This resource will support counseling that considers not only those conditions for which there is a genetic test, but also all those breed disorders/ characteristics that impact health and well-being in breeds. Our Steering Committee includes: Brenda Bonnett, CEO, IPFD; Aimee Llewellyn-Zaidi, HGTD Project Director, IPFD; Diane Brown, AKC Canine Health Foundation; Matthew Breen, North Carolina State University; Cathryn Mellersh, Animal Health Trust; Sofia Malm, Swedish Kennel Club; Wim van Haeringen, VHL Genetics, Netherlands; Sue Pearce-Kelling, Optigen; and Eddie Dzuik; Orthopedic Foundation for Animals (OFA). IPFD, our Partners and other stakeholders in this initiative recognize the input and work of many other experts and organizations in addressing the use of DNA tests in dogs. The Harmonization initiative is working to further engage numerous experts to participate in panels to develop the resource, provide evaluation of tests and work to advance genetic counseling. IPFD actively engaged Leadership Sponsors (see below) to help develop the HGTD Quality Database. These collaborators include international genetic test providers (GTPs), academic institutions, the Hereditary Disease Committee of the World Small Animal Veterinary Association and other important dog health organizations. A prototype was presented at the 3rd International Dog Health Workshop and at the 9th Canine and Feline Genetics and Genomics meeting in Minnesota, May 2017. Beta testing of the Quality Database was completed in early 2018, and it was launched on 7 May 2018. Since the launch, there has been a surge of interest from both the public, and potential new collaborators. The HGTD database was the culmination of months of hard work, building of new collaborations, fundraising, and data management. One of the major IPFD projects, it arose from discussions at the International Dog Health Workshops (IDHWs); the HGTD is a proud achievement, exemplifying the IDHW tagline: Information – Collaboration – Action! We have been pleased to find that people are already using the HGTD Database to help find the right international genetic test provider, and testing information, for their dogs. By publishing details on a test provider’s measure of quality, business and research information, and tests provided – as well as information on hundreds of breed-specific DNA tests – dog owners and health professionals are able to make the most of this project. The growth and development over 2018, and the positive interest from diverse professional and public media - from JAVMA to The Atlantic - has been reassuring that this project is both timely and needed in the world of genetic testing. It has also become apparent that IPFD has an important role to play as an independent voice in discussions on the complex world of genetic testing. See, for example, our response to an article in Nature, where we are able to provide a balanced view of issues. See also, a Improving Canine Genetic Testing, a discussion on standards for GTP labs and broader challenges. This is a field with a diverse array of stakeholders, and encouraging discussions will continue to be part of our role. As of December 2018, Harmonization of Genetic Testing for Dogs database currently holds basic information for 59 genetic test providers across 17 countries, with information on quality measures and accreditation for 26 active and participating test providers - including non-profits, academic institutions, and for-profits. Our searchable genetic phenes database currently holds information on 300+ phenes across all breeds/types, and provides a plethora of information on each phene: links to OMIA, gene + mutations, a simple and advanced disease description, inheritance details, links to original publications, patents/licenses, comments from the original researchers/experts on application, and breed specific information (such as research/validation) - where possible. Our projects moving forward in 2019 are to continue to engage with researchers, veterinary experts, and test providers, and also to focus on the development of an expert panel for reviewing genetic testing resources, as well as interactive educational tools for consumers. In addition, we are looking for collaboration to address some common problems across genetic testing, such as nomenclature of genetic tests - which has been a significant challenge in harmonizing across international researchers and test developers. We are pleased that we continue to have sponsorship and support from many of our key Leadership Sponsors to develop our work for 2019. We would welcome anyone with an interest in contributing to, or participating in, the HGTD project to contact us. We are particularly keen to engage with academic and research institutions providing testing, who are concerned about ensuring genetic testing is a beneficial and responsible resource. Key Partners and Leadership Sponsors Read more about IPFD Partners and Sponsors Other potential sponsors and collaborators are welcome to contact us to explore opportunities. Contact: IPFD CEO Brenda.Bonnett@ipfdogs.com or Project Director Aimee.Llewellyn-Zaidi@ipfdogs.com “Wisdom Health and the Wisdom Health logo are trademarks of Mars, Incorporated and its affiliates. Used with permission.” -
From Information and Collaboration to Action: 4th IDHW
Brenda Bonnett posted a blog entry in Brenda's Blog
Thanks to our co-hosts, The Kennel Club, the 4th International Dog Health Workshop was a great success. The consensus seems to be that the IDHWs just keep getting better and better. This is due in great part to the efforts of the attendees - decision leaders from 18 countries, representing all stakeholders in dog health and welfare - including representatives from research, the veterinary world, welfare organizations, kennel and breed organizations, and more. Stellar plenary speakers set the tone for intense and productive breakout sessions in the various themes. The themes were: Genetics, Breed-Specific Breeding Strategies, The Concept of Breed and its Impact on Health, Supply and Demand, and Extremes of Conformation. Below you will find links to fantastic pre- and post-workshop materials. Be sure to check in to DogWellNet.com and follow us on Facebook and Twitter for important updates from the several working groups who are already moving ahead with needed actions. As seen in the word cloud from our participants, a key aspect of this meeting is collaboration and networking. Coming together with others who are dealing with similar challenges and who share a commitment to health dogs provides a boost of energy for both cooperative efforts as well as the day to day work by these committed dog people. Below you will also see reports and write ups about the 4th IDHW, and there will be more as the work continues. Thanks to all who attended, and we will keep you informed on developing plans for the 5th IDHW in 2021. 4th IDHW Pre- and Post-Meeting Resources From pre-meeting reading material to posters and slide presentations from the workshop, we've compiled materials from the 4th IDHW, so that participants can refer back to them - and so that those who were unable to attend can also benefit from this impressive collection of downloadable resources. Pre-Meeting Resources | Post Meeting Resources Articles on the 4th IDHW Vet Record News: 4th IDHW workshop - "Improving the health of pedigree dogs" Lance Novak, Executive Director, Canadian Kennel Club: From My Side of the Desk: Canine Health and Wellness Several articles by Ian J. Seath of the Dachshund Breed Council (DBC): My report on the 4th International Dog Health Workshop for Our Dogs My presentation to the 4th International Dog Health Workshop (IDHW4) Breed Health Strategies – Addressing the challenges: My July 2019 “Best of Health” article The why and how of Breed-specific Health Strategies – “Best of Health” June 2019 Aimee Llewellyn-Zaidi's Report from the Genetic Testing Theme, from the 4th International Dog Health Workshop Canine Genetics and Epidemiology Journal. As following the 3rd IDHW, we are compiling a report on the 4th that will be review and published by our collaborating partners at CGE. If you haven't seen the previous article, check it out here. Global Pet Obesity Initiative After an overwhelming show of support by attendees of the 4th IDHW, IPFD has confirmed its support of the Global Pet Obesity Initiative Position Statement (launched by The Association for Pet Obesity Prevention (APOP)) calling for the veterinary profession to adopt uniform nomenclature for canine and feline obesity. IPFD is currently in discussions with APOP to look at ways to collaborate on the important issue of canine obesity. -
COVID-19 - a novel experience for dogs and people
Brenda Bonnett posted a blog entry in Brenda's Blog
Sources of accurate and relevant COVID-19 information for your dog, your puppies and you. In the face of the great uncertainty surrounding COVID-19 and its impact on pets and pet owners, many veterinary and regulatory organizations have been providing excellent information and advice, as have kennel and breed organizations. It is important to remember that recommendations and restrictions vary depending on location and owners need to access and follow local recommendations, especially as to issues around accessing veterinary care. An additional challenge is that the advice and situation continue to change rapidly and what was known, thought or suggested last week may not hold next week. There are some aspects that apply regardless of location... including what we know (a little) and don't know (a lot) about possible transmission to or from animals and humans. As with all information about this novel corona virus there is a lot of uncertainty about COVID-19 and pets; basically we simply are leaning as we go. Be very cautious about discussions and dire predictions on Facebook and social media from those who likely do not have the appropriate level of expertise. Putting your trust in the types of sources described below is your best bet. At a local level, dog owners can look for information from their regional veterinary association and even your own veterinarian maybe providing updates. For an example from the Canadian Veterinary Medical Association, you can see a short video and article here. Prof. Scott Weese of the Ontario Veterinary College is referenced in that article and he has a recent blog post where he suggests that, in the face of the uncertainty and with an abundance of caution, "Social distancing and dog walking are compatible… with some common sense". Dr. Weese says, "To me, social distancing is a whole household activity, not just a human activity. If I wouldn’t go and shake someone’s hand, why would I let the same person pet my dog, and then touch the same spot on my dog myself right away? " It is all about doing everything we can to reduce risk. Be sure to keep up to date on recommendations and restrictions in your area. For breeders, there are all the issues as for owners in addition to some major concerns about breeding, and rehoming litters. Many of our partner national kennel clubs have been providing information and updates. We have been sharing these on our channels, as again, some issues are the same globally; others are defined regionally. See, e.g. Breeders and coronavirus (COVID-19) FAQs from The Kennel Club in the UK, or Placing Puppies in the Age of COVID-19: Safety Advice for Breeders from the American Kennel Club. There are many broader impacts for dog welfare and human-dog interactions that are developing with the COVID-19 situation. Please check out Brenda's Blog: "DOGS ARE FOR LIFE, not just for Coronavirus." Within that blog you are also directed to an excellent discussion of unintended consequences from IPFD collaborator Ian Seath. Our IPFD Board member and President of the German Kennel Club, Prof. Dr. Peter Friedrich, has posted a heartfelt statement that discusses many of the current challenges and those that we have left to face, even when we think things are starting to return to normal. (In German, but perfectly understandable with google translator.) Below are some links to sites and organizations that are doing a great job with information at an international level pulled together by our IPFD COO, Monique Megens, a Dutch veterinarian, living in Spain, and former president of FECAVA, one of the organizations on the front lines in Europe. Mid-April 2020: What do we know about dogs and COVID-19 virus? Although several dogs have tested positive to COVID-19 virus following close contact with infected humans, to date, there is no evidence that dogs play a significant role in spreading the disease. Therefore, the OIE (World Organisation for Animal Health) states there is no justification in taking measures against companion animals, which may compromise their welfare. When people are sick with COVID-19, when possible, close contact with dogs should be avoided; the dogs should preferably be taken care of by another member of the household, taking appropriate hygiene measures into account. Studies are underway to better understand the susceptibility of and risks for other dogs. To stay up-to-date and for more information regarding dogs and COVID-19, go to the OIE website. Can I still visit my veterinary surgeon In many countries, veterinarians are considered to be an essential profession by their national authorities; therefore in most countries you can still visit your vet. However, some vets only see urgent cases; you should always call beforehand. For more information: IPFD’s collaborating partner the Federation of European Companion Animal Practitioners (FECAVA) together with the Federation of Veterinarians of Europe (FVE) have published advice for pet owners for visiting the vet. Information for veterinary teams can be found locally and regionally at, for example from American Veterinary Medical Association (AVMA) and at IPFD’s collaborating partner the World Small Animal Veterinary Association's (WSAVA) website. In all the craziness and concerns of this pandemic, dogs are a great support to their families. Let's remember them in all the changes, planning and considerations we have for ourselves. We are all in this together. Stay safe . OTHER RESOURCES: En Francais - La Newsletter de la Centrale Canine - beaucoup d'excellentes ressources auf Deutsch - und weiser Rat von unserem IPFD-Vorstandsmitglied und Präsidenten des Deutschen Kennel Clubs, Prof. Dr. Peter Friedrich, Präsident des VDH. Corona virus -
DogWellNet Digest: Issue #31 - 26 June 2020
Dave St. Louis posted a article in DogWellNet.com Digest
News & Highlights 'Pandemic Puppies' and COVID-19: How to Navigate This Complex Issue Make a Donation Stay Informed! -
DogWellNet.com Digest: Issue #9 - 25 July 2017
Dave St. Louis posted a article in DogWellNet.com Digest
In This Issue: News & Highlights So much content...So little time: Activity Streams on DogWellNet.com Stay Informed! -
DogWellNet.com Digest: Issue #4 - 15 November 2016
Dave St. Louis posted a article in DogWellNet.com Digest
In This Issue: News & Highlights Spotlight Helpful Hint Stay Informed -
DogWellNet.com Digest: Issue #2 - 25 July 2016
Dave St. Louis posted a article in DogWellNet.com Digest
In This Issue: News & Highlights Spotlight Helpful Hint Stay Informed -
Continuing with the initiatives of the IPFD Student Project, ‘A Veterinarian’s Role in the Ethics and Welfare of Breeding Dogs’, this interactive educational module was created entitled, “How Can You Promote Informed Decision-Making in Acquiring a Purebred Dog?” in collaboration with Jane Shaw, DVM, PhD, Colorado State University, and Brenda Bonnett, DVM, PhD, International Partnership for Dogs. -
HGTD, and IPFD, were thrilled to be able to send our very best wishes and acknowledgements to Prof Frank Nicholas, on the 25th Anniversary of the Online Mendelian Inheritance in Animals (OMIA) resource. (see Brenda's Blog) Collaboration with, and integration of OMIA's information is vital for a lot of what HGTD is able to do - and fundamental to animal genetics researchers the world over. OMIA is a catalogue/compendium of inherited disorders, other (single-locus) traits, and genes in 251 animal species. OMIA is a great example of collaboration in action - authored by Professor Frank Nicholas of the University of Sydney, Australia, but with expert input and help from many people over the years. For HGTD, it has provided a standardized, unique identifier number for the hundreds of phenes we list on the database, as well as additional information curated by Prof Nicholas and his contributors over the years. The OMIA number is something that can be recognized by genetic researchers across all countries, as a universal reference. It is a resource used by so many HGTD stakeholders, and accepted as something that just... feels like it has always existed. While it is hard to imagine creating HGTD and other resources without OMIA in place, it is easy to take fundamental resources like OMIA for granted that they will exist forever, always expanding, and up to date, without thinking about the challenges required to create them, and the perseverance to keep them going through the years. This concept was in my mind this week as I tackled adding in dozens of new breed-specific research publications and references, as well as updating OMIA references to phenes in the HGTD database. As an integral part of HGTD's principle of transparency in reporting, providing up to date breed-specific and breed-relevant publications from peer-reviewed journals, as well as additional input from geneticists and researchers is a critical, but also a challenging and time-consuming aspect of maintaining the HGTD databases. It requires regular review of OMIA, as new OMIA numbers are generated for new canine single-locus traits, collaboration with researchers who can provide important journal references, and the time and expertise to write and reference technically/clinically accurate phene descriptions, with language and wording that is accessible and clear to a wide audience. This is part of why it was so important from the beginning of the Phenes database development, that we worked to include gene and mutation information for each phene, at a breed-specific as well as testing level. And, why we offer 2 descriptions for as many phenes as possible: a more technical/clinical description for our veterinary and research users, as well as a more real-life experience summary for dog owners and breeders. It might be us who are putting this information in place, but it is only with the collaboration, and expert input from researchers and experts that we are able to have such a robust and responsive resource. Thinking back to our friends at OMIA, I wonder (hope), that IPFD and the HGTD databases will in time be seen as a standard resource and reference for our diverse community, and be celebrating such an auspicious anniversary as OMIA, in the future. With continued thanks, and appreciation to: (puppy photo thanks to Mateja Lemic via Pexels) -
Not all puppies from health-tested parents will be healthy!
Brenda Bonnett posted a blog entry in Brenda's Blog
And not all dams and sires with 'clear' test results will be good choices for breeding. Oh, would that life and breeding decisions could be made easy! But every experienced breeder knows that nothing is simple. Breeding and inheritance and health and temperament are very complex issues - each on their own - and combined they constitute a puzzle with no guaranteed solutions. With the increased availability of genetic testing, with its media-inspired aura of high-tech infallibility and direct-to-consumer marketing campaigns, there has been a rush to embrace it as THE most important pre-breeding test. It is probably underpinned by the vague hope of breeders that IF they spend their money and do all the possible genetic tests, they will have fulfilled their 'due diligence''. Many of my colleagues and I have repeatedly reminded the breeding community that, in spite of genetic testing being an extremely important decision-making tool, it is crucial that attention be paid to conditions that are considered important for a breed - regardless of whether there is a 'DNA test' for the condition, or even any test at all The Big Picture is crucial. I described in another blog a genetics symposium in Canada in November 2019. During discussions with committed breeders, at we came to some very important questions. For example, everyone says they want healthy animals with good longevity. But think about these items before you nod your head: How many breeders could say that those are the primary criteria they use when selecting mating pairs? Is there good evidence in your breed that the main focus of breeding has been on producing healthy, long-lived offspring? When breeders choose inbreeding or line-breeding is it to improve health and longevity, or, more likely, aimed at fixing specific traits, often to do with appearance? These questions are not meant as any judgement but to provoke critical, rational, logical thinking about breeding decisions which are, for better or worse often influenced by something else. Primarily, people need to look honestly at the history and culture of breeding and admit that, as for anything in life, a) saying and wishing and hoping is not doing; and b) you cannot achieve a theoretical or even heartfelt goal if your actions are in direct opposition to its achievement. I say I am committed to being slender and fit and then spend all my time in front of the computer and maintain a deep and satisfying relationship with potato chips. But at least I am not shocked when the slender-fit thing just doesn't happen. Our IPFD friend and collaborator Ian Seath posted another recently called 'Health-tested does not mean healthy'. And rightly highlights that health and longevity (or 'healthgevity') is a function of many factors beyond breeding or genetics. Owners must do their part to maintain health and not push all blame for ill-health to breeders. E.g. the well-loved, but morbidly obese Pug in this shot, had, by nature and breeding, specific health risks, all, no doubt aggravated by its body condition. All stakeholders in the health and welfare of individual dogs and breeds need to contemplate their roles and take responsibility. More coming on the topic of health testing and health, soon. -
Happy Birthday, OMIA - a lynch-pin in the development of genetic testing
Brenda Bonnett posted a blog entry in Brenda's Blog
Congratulations to the University of Sydney and OMIA - the Online Mendelian Inheritance in Animals database. 25 years old 25 May 2020. Check out the celebration webpage here. This amazing resource underpins research and education on genetics in many species and has been a key support for advancement in the world of dog genetics and genomics. The development and maintenance of this fantastic database is due to the input and support of many academics, researchers, and others, many of whom volunteer their expertise and time. But it would not have existed or been maintained without the commitment and passion of Frank Nicholas. We gratefully congratulate him on this milestone. OMIA is a collaborating partner of the IPFD, and we have been coordinating and linking with them to maintain the quality of the Harmonization of Genetic Testing for Dogs database and resources. The OMIA numbering system is vital for international collaboration and critical to harmonizing genetic phenes across research and industry. IPFD is very proud of and grateful for this association and will help celebrate this event with a donation via the OMIA site. Why not join us in recognizing this important and necessary achievement? -
HGTD Update: 12 May 2020 Since the last blog, we’ve had additional expert review of many Breed Relevancy Ratings (BRRs) – particular in commonly tested eye conditions, and ataxias. As we are growing our expert out-reach for input into BRRs, we are pleased to note that there is consensus between experts self-reviewing their tests as well as peer-reviewing each other. This adds reassurance to us that the current BRR estimation of combining what we can learn from research publications, phene discoverer’s expert opinions, and informal peer-review between geneticists, is working. So far, we have been able to estimate BRRs for more than 1167+ of the 2684 possible breed-specific test combinations. To support BRRs, we are also adding in additional and newly published breed-specific publications and other references in the Breed Specific Information area of the generic phenes. You can find any breed-specific publications or other resources via the "Search by Test/Disease", under the Researched Breeds section. One example is for Spinocerebellar Ataxia, CAPN1-related – where you can see for 3 breeds, there are links to further information, breeding strategies, and researcher comments and publications: Check out in the HGTD by searching on Ataxia...CAPN1 HERE or go directly to the OUTPUT HERE. Our lists of peer-reviewed publications and referenes are growing by the minute. As a reminder, in the Test/Disease (Phenes) section, you can find the original mutation discovery paper (where known) as well as a selection of other relevant references. As this expands, we are exploring other ways to capture this information to be able to share it in a useful way for you. If you are a researcher, or know of a publication we don’t currently list - especially any breed-specific references, please let us know! We try to include the reference as well as links to open-access resources or a pdf, whenever possible. You can email me at aimee.llewellyn-zaidi@ipfdogs.com Terrier image by P. Kirsi, from Pexels
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We get questions about how we ensure the quality of the information available on HGTD. It can actually be very challenging, and we rely on having good processes, and collaboration when developing content. To meet the IPFD principle of transparency, we are starting a series of blogs to describe how we manage this resource. We hope to then provide a regular news feed on HGTD developments and changes, to give you all an insight into this work. To get started, here is a little insight into running and maintaining HGTD. How do new genetic test providers (GTPs) join? GTPs reach HGTD as part of the wider IPFD network, research conference outreach, and direct contact. Leadership Sponsors, Sponsors and Participants include commercial providers, non-profits, and large and smaller research groups. Donations from our participants and sponsors to help off-set some of the running costs and development of HGTD. All data received is checked for accuracy, and legitimacy. GTPs who offer ISAG, or other accreditation are checked. All testing information is reviewed to standardize nomenclature and catch any errors or mis-translations. Regular reviews of all databases (GTP, Tests, and Phenes) ensure changes in the industry or emerging research is captured, and disseminated. Quick, and accurate publication is our goal. We aim to have new GTP information, and updates added within 48 hours, but this is often much faster. Publication allows for peer-review, and is key to an open and transparent system. What does the general running work look like? As our GTPs are international, we harmonize across different languages, nomenclature, and national/regional accreditations. We also collaborate with groups such as OMIA and ISAG to improve consistency and harmonization across the industry. At any given time, we are the caretakers of information on dozens of GTPs, hundreds of phenes, and thousands of lines of associated data. All of which have to be checked against independent sources, and regularly reviewed to reflect the fast-paced changes in the genetic testing world. What if I want to help? Use HGTD. The most important way to help is to use HGTD, and tell your friends about how helpful you find it. If we can improve it, let us know. Recommend, Donate! If you have a favorite GTP and they aren’t participating, get in contact with us to help us encourage them to become a part of HGTD. If you have the ability to donate, even a small amount, you can choose to direct it towards IPFD, or directly to HGTD. Either way, you will be supporting us in building resources to improve dog health and welfare. Be part of our Collaboration Community. You can send questions about tests, research papers, experience that your breed club has had, or other feedback to us. We work hard to respond quickly, and while we can’t include everything, we always aim to integrate robust new information. Further information/References: Sponsors, Participant, and databases can be viewed in the Genetic Testing section of IPFD: https://dogwellnet.com/ctp/
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IPFD at American Veterinary Medical Association 2019 Washington DC
Brenda Bonnett posted a blog entry in Brenda's Blog
Several IPFD collaborators are speaking at the AVMA conference this weekend! Thanks to IPFD collaborator, Dr. Jason Stull, there are sessions focusing on Canine Genetics in the Dr. James H. Steele One Health stream, including: Angela Hughes DVM, PhD from Wisdom Health is presenting Utilizing Genetic Panel Testing in Dogs for Breed and Disease and IPFD CEO Brenda Bonnett, DVM, PhD who is talking about Genetic Testing to Improve Canine Health: The Big Picture and why this truly needs to be considered from the One Health approach. Hint: We care about the dogs, but it is people who complicate everything!! In addition, Theme Leader at the 3rd International Dog Health Workshop in Paris, Jason Stull VMD, MPVM, PhD, DACVPM, is giving a series of talks on infectious disease concerns in veterinary practices, including, e.g. The Dummies' Guide to Preventing Hospital-Associated Infections. Harmonization of Genetic Testing for Dogs (HGTD) collaborator, Kari Ekenstedt DVM, PhD, is delivering a whole afternoon of talks on clinical genetics, including Practical Applications of Genetic Testing in Dogs and Cats. Hope to see vets and vet techs that are keen to expand their practical knowledge about dogs and genetics... See a follow-up: -
IPFD and DogWellNet 2019-2020: Looking Back and Moving Forward
Brenda Bonnett posted a blog entry in Brenda's Blog
In our final installment of the Digest for 2019, we are putting the spotlight on 2019 milestones, and looking forward to 2020 – which promises to be a pivotal year for IPFD and DogWellNet.com. In 2019, our fifth full year of operation, we focused our efforts on several key initiatives, including: the Harmonization of Genetic Testing for Dogs (HGTD); the 4th International Dog Health Workshop (IDHW); the continued growth of DogWellNet.com and our online community. We provided an independent voice in addressing complex and often controversial challenges, including "Hot Topics" such as canine genetics; and shared resources e.g. on health and welfare issues in brachycephalic breeds. See other interviews and news reports featuring IPFD here. As a start up non-profit five years ago, we represented a good idea, with an admirable mission. Many were enthusiastic about the concept, but perhaps unclear about the details of what could be accomplished. IPFD developed based on a strategy of 'if we build it, they will come'. The progress has been gratifying, but never fast enough for me, personally. The acknowledgement of the need for multi-stakeholder, international collaboration and action is widespread; but the realities of the dog world and the demands of local, regional, and national responsibilities of our volunteers and collaborators continues to pose challenges. As we move into a phase of enhancing stability and sustainability, we have a lot to celebrate and great potential on which to capitalize. The word cloud created from participants' comments from the 4th International Dog Health Workshop exemplifies many of our issues, goals, and efforts We have a substantial focus on science and evidence, but we never forget that the human element underpins everything we do. Our Spotlight video in December's Digest shows a softer side, reminding us that it is our love and appreciation for dogs that motivates us. People are always the strength of an organization, and now is a good time to acknowledge and thank the small but committed team of consultants who do the lion's share of work at IPFD. Please check out their profiles and read more about their efforts, below and in the Digest. The IPFD Board has gone through a transformation in 2019, with three members transitioning off the Board and five enthusiastic new Board members joining. The Board now comprises both old friends and new faces with renewed energy and purpose to help launch IPFD into the new decade, capitalizing on existing strengths and addressing ongoing challenges. Bios for the Board are here; we can all look forward to learning more about them in our 2019 Annual Report, and hearing from them in articles and blogs. In the spirit of the season, below are some highlights from 2019 – these could make for some great holiday reading! Thanks to everyone who has supported IPFD and participated in our work in 2019. And here's to a stellar 2020... as we leap ahead with great aspirations. New IPFD Contributors We welcomed two new Contributing Partners in 2019: The Canadian Kennel Club (January) Raad van Beheer (The Dutch Kennel Club) the official kennel club of The Netherlands (February). A new two-year Sponsor, the Morris Animal Foundation (July). And several Non-Breed Specific Collaborators, which are organizations serving health and welfare interests for all breeds: European School for Advanced Veterinary Studies (ESAVS) (June) Global Pet Obesity Initiative (August) And going into 2020, we have renewed and ongoing contracts with all existing Contributing Partners! Harmonization of Genetic Testing for Dogs (HGTD) The HGTD Project has seen significant growth in 2019, and currently lists 76 Genetic Test Providers (GTPs) across 22 countries, worldwide with 42 currently participating or starting their participation. Thanks to Project Director Aimee Llewellyn-Zaidi! We have made several improvements to the information we record for both genetic test providers and test information. This includes clearer information on what laboratories are used for outsourced testing and when information has been updated by GTPs. Thanks to our App developer Michael Edwards (Coding Jungle), we continue to further automate the updating process and add on new functions. See further details on HGTD in the Digest. In 2020, in addition to expanding engagement with GTPs, we will integrate various projects (Expert Panel, Health Strategies Database (HSDD), the Get a GRIHP Program) to enhance breed-specific information and outputs. Read about these initiatives in Brenda's presentation under Breed-Specific Health Strategies at the 2019 4th IDHW, here. 4th International Dog Health Workshop (IDHW) The IDHWs bring together a wide range of stakeholders in dog health, science, and welfare to improve international sharing of information and resources, provide a forum for ongoing collaboration, and identify specific needs and actions to improve health, well-being, and welfare in dogs. IPFD is responsible for the International Dog Health Workshops and partners with other organizations who manage meeting logistics. Access the amazing resources from the four IDHWs here. The 4th IDHW, co-hosted by the Kennel Club in Windsor, UK, in May/June 2019, included more than 130 decision leaders from 17 countries, who joined us to share their experiences and expertise across five Themes addressing some of the most pressing issues in the dog world. We’ve compiled pre- and post-meeting resources here, both for the benefit of workshop participants and for those who were unable to attend. We continue to see the dividends of the important work done at the first three IDHWs (read more in our publication from the Paris 3rd IDHW and look for a new publication in the Journal of Canine Epidemiology and Genetics in 2020), and Working Groups have begun work on issues addressed at the 4th IDHW earlier this year. The 5th IDHW takes place in 2021, with the date and location to be confirmed soon! DogWellNet.com Our internet platform, DogWellNet.com, is an open access, ever-expanding information hub, providing links, documents, and additional resources to breeders and others in the dog world. For an overview of the site, including an explanation of key content areas and features, please visit DogWellNet.com: At A Glance. Although almost all DogWellNet content is available to guests, we encourage readers to sign up as members on the site. As of the publishing date for this issue, more than 1,200 people have signed up on DogWellNet.com, including more than 500 Members and 700+ Advanced Members. One of the popular resources on the site is the Breeds Database, ably overseen by our Content Manager Ann Milligan. A former breeder, and current judge, Ann is always thrilled to get information from breed clubs and breeders, as we continue to expand this resource. In 2020, there will be further integration of material from the breeds database with our other initiatives (HGTD; HSDD, etc.). DogWellNet Digest This is our eighth 2019 issue of DogWellNet Digest – a collection of the latest news from IPFD and DogWellNet.com. A link to each new issue is emailed to all IPFD Members and posted to our social media accounts, and all previous issues are archived on DogWellNet.com. See also IPFD in the Media for excerpts or links to published articles, etc. that reference IPFD or DogWellNet. IPFD Social Media In 2019, our social media presence expanded further into the dog world with several targeted campaigns and a growing following of our Facebook, Twitter, and LinkedIn accounts. Thanks to Dave St. Louis, our Communications Specialist, for keeping us in touch with our Partners, Members, and the dog world, in general. Another key online tool is our video resources. See our latest, a feel-good offering for the season, and tantalizing, early glimpse of our 2019 Annual Report. Enough looking back, let's talk about... Moving Forward in 2020 With additions to HGTD and other genetic counseling resources, implementation of the Expert Panel, creation of the HSDD, planning for the 5th IDHW; enhanced activities with our revitalized Board, ongoing outreach with our Partners and Sponsors...the possibilities are exciting! All the best for the holiday season and Happy New Year from IPFD...where every year is the Year of the Dog. -
After watching to play the video again use the controls and select "Replay" ⟲... or select from other displayed IPFD videos. It seems that every day - in the world of dogs and the world beyond - we see decisions made that may work for part of a problem, but because they do not take into account the complex reality of the bigger picture, they are unlikely to be fully effective. Every step we take at IPFD reminds me of this interconnectedness - and of the need for IPFD's international, multi-stakeholder approach. And about how grateful we are for the Partners, Sponsors and collaborators who make our work possible. We have created a short, 'lite' video to highlight these issues and then expand on examples below. IPFD's International Dog Health Workshops have helped to pull the vision of and methods by which the goal of better health and welfare for dogs is achieved. Breed Health Strategies are the foundation of planning for health and welfare improvement in dogs. A strategy for a breed may include any, or all, of the following: disease, longevity, genetic diversity, conformation, temperament, working ability. See Breed-specific Breeding Strategies - 3rd IDHW follow-up and a subsequent document which provide specifics for establishing a sound, workable strategy. These documents define projects and processes that focus on the objectives to safeguard and improve the future of a breed. (Breed Strategies IDHW content is attributed to Ian Seath, dog breeder, chair of the Dachshund Breed Council in the UK, and leader of the Breed-Specific Health Strategies theme at the IPFD International Dog Health Workshops (IDHW).) Also see IPFD CEO Brenda Bonnett's plenary talk at the 4th IDHW: Get a GRIHP on Breed Health, which addresses the complexities of big picture health concerns that must be addressed by collective information and actions. From the Genetics theme-based topics discussed at the 4th International Dog Health Workshop, a pressing need for genetic counseling experts emerged - experts to provide meaningful evaluation of and advice on breed-relevant use of the growing number of DNA and health screening tests available to dog owners/breeders. A key action/project at the workshop was interrogating the concept of “validation” – which pulled together many specific genetic test issues. It was decided that creating a model for addressing Validation for genetic tests would be the best use of time for the workshop. This was effective in guiding discussion to identify specific actions/projects moving forward. The questions from the breed community: How do we know what tests to use? How can we trust the test results? See the Report from the Genetic Testing Theme, from the 4th International Dog Health Workshop. Tools are needed! Why? Direct-to-consumer genetic tests have provided greater access to many different breed-specific and general genetic tests for dogs. This has raised concerns from owners and breeders who need more guidance and direction in making informed testing decisions. To help with this, the HGTD in December of 2019 added relevance ratings to the interface. Currently, the relevance rating is determined based on a wide-variety of evidence sources. This includes peer-reviewed research papers, recommendations from the original researchers/test developers, input from additional experts including veterinary specialists, and breed experts. It is important when considering the ratings to understand that this effectively indicates how much we currently know or do not know about a specific test for a specific breed. This does not necessarily indicate how “good”, or “bad” a test is. It also does not indicate the clinical importance of a test. So who is doing what in the big picture - of course management of dog's well-being includes and goes beyond DNA tests - health screenings matter, temperament matters, conformation matters... The Health Strategies Database for Dogs is in the works to augment health information available on DogWellNet... stay tuned. The ongoing creation of tools and educational content to improve the health and welfare of dogs by kennel and breed clubs, and work done by groups of breed enthusiasts drives the big picture forward. In the Blog post, Breed Health... What is your vision?, the take-away message is, undertake actions and make decisions that can impact the dog world in beneficial ways. We continue to promote international efforts on the challenges for dogs; we work to bring together stakeholder groups and organizations.
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Genetic Diversity: The Big Picture and Challenging Issues
Brenda Bonnett posted a blog entry in Brenda's Blog
What a great weekend of education - with the Canadian Kennel Club and about 170 participants, including breeders with a range of experience from over 40 years to novices. Speakers Dr. Kari Ekenstedt, a geneticist from Purdue University in Indiana and IPFD CEO Dr. Brenda Bonnett covered 'everything you need to know to understand genetic testing' in a clear, concise and entertaining series of talks. Interactive discussions with the many knowledgeable, committed attendees were interesting and thought-provoking. Read more here. Download the schedule here: CKC Seminar Schedule Final.pdf My talks covered the Harmonization of Genetic Testing and the many initiatives IPFD is pursuing to support breeders, as well as a talk together with Kari on Ethics and Welfare. In addition, both speakers addressed issues about genetic diversity, selection and inbreeding. Dr. Ekestedt's presentation was a primarily science-based coverage, including description of various tools, including calculation of Coefficients of Inbreeding (COIs). My talk on Population Health and Diversity presented a more conceptual coverage of diversity (see below), including examples from other species. Both talks included practical suggestions for including these aspects in breeding decisions, but this was also meant to promote discussion and consideration by breeders as they examine their own role, as well as the roles of breed and kennel clubs in promoting and conserving health and longevity in their breeds. It is clear that many breeders are struggling with definitions and implications of genetic diversity, inbreeding and line breeding, and with resolving new information from the fast-advancing world of genetics and genomics with long-held attitudes and practices that are firmly embedded in dog breeding culture. Below are some key points and challenging issues raised in these talks and in the interesting and frank discussions with participants. Thanks to the Canadian Kennel Club and all the participants for a stimulating and enjoyable weekend of continuing education! Congrats to the CKC team who put on a great event. Stay tuned as we will post on DogWellNet.com the video of my talk and links to the rest of the program - hopefully in early January 2020. Additional reading on Genetic Diversity Understanding Breeds as Populations - J. Bell What we can learn from each other: Show Greyhounds Is Crossbreeding a Part of the Plan for Bulldogs -- Genetic Considerations (references Pederson Study) Small Population Breeds and Issues of Genetic Diversity - J. Bell -
Harmonization of Genetic Testing (HGTD) 2019 Summary
Brenda Bonnett posted a blog entry in HGTD & Genetic Testing
The HGTD arose from discussions at the IPFD International Dog Health Workshops (IDHWs); it is a proud achievement, exemplifying the IDHW tagline: Information – Collaboration – Action! In 2019, the HGTD project could be summarized in one word: Growing. We’ve consistently grown our list of genetic test providers (GTPs). Participating GTPs have provided information on their accreditation, expertise, and practices – all of which helps individuals find a GTP that has the quality measures most important to them. The generic phenes database provided a centralized resource for researchers, vets, and owner/breeders, spurring unexpected benefits. We’ve seen more consistency in test naming among international providers, benefiting owners seeking testing information. It also allowed international researchers to spot industry-wide challenges, and have them addressed through a centralized platform. To better support dog owners, the veterinary community, and dog health advisors, we introduced Breed Relevancy Ratings across genetic tests. The HGTD database relevance rating indicates the amount of available evidence supporting the relevance of a specific genetic test for a specific breed/type. Currently, the relevance rating is based on a wide-variety of evidence sources. This includes peer-reviewed research papers, recommendations from the original researchers/test developers, input from additional experts including veterinary specialists, and breed experts. It is hoped that, by being more informative about what we currently know or do not know about a specific test for a specific breed, that dog health advisors and owners can make more informed decisions. The collaboration across the dog world, and the participation of those in the testing industry, dog owners, and experts around the globe, has helped to shape our achievements for 2019 and develop exciting plans for 2020. -
The wonderful thing about our IPFD collaborator, brilliant person, and incredibly knowledgeable dog person Ian Seath, is that, when major issues are at foot, my procrastination at commenting is rewarded by him posting an article that says almost everything I wish I would have said. All that is left for me to do is to add a few comments and send it out. This is very true for his latest installment on his platform Dog-Ed: COVID-19: A (dog) world of unanticipated consequences Ian does a great job of describing our situation, with relation to other experience of times of disruption: "In the world of business and leadership development, there’s a concept that’s been around for a while that describes the world we’re in. It’s VUCA, which stands for Volatile, Uncertain, Complex and Ambiguous. ...There are no simple solutions in a VUCA world; we need to understand that decisions made in one part of a system can have quite surprising and unanticipated consequences elsewhere. Often, those consequences will be counter-intuitive." He goes on to describe different possible outcomes and ramifications for dog registrations in the UK - a situation IPFD is monitoring together with our many KC Partners from different countries. As Ian suggests, things could go either way. In Iceland, after the financial collapse in 2008, breeders were worried they would not find homes for their puppies; in fact, demand was higher as people realized they would not be able to travel outside the country as much and embraced the new reality and options. It is clear that there is an uptick in adoptions in North America (and UK as described in Ian's article). And while we totally agree that pets are fantastic companions, we have to think about 'unintended consequences'. Where did your Covid-dog come from? And what happens when life goes back to normal? Ian does an excellent job describing concerns about sourcing of puppies, supply and demand, rescues, and more. In every case it is, at least potentially, a 'for better and for worse situation'. Firstly, being able to determine the quality and welfare of dogs from various sources of dogs is an ongoing challenge, possibly increased during the Covid situation when people are in a rush to get a pet. For example, some sources, especially with online sales, even if promoted as 'rescues', may be re-sourcing puppy-farmed dogs. Beyond that concern - in North America there is a generally positive response to news that shelters and rescues are emptying out... which is great as long as there is not a flood back to shelters when economic hardships hit if restrictions continue, or if, when people return to work, they suddenly remember why they did not really have the capacity to be responsible dog owners. And I saw a report that dogs adoptions were not allowed now in France, for various reasons, no doubt - and that approach may both prevent some and create other problems. Beyond immediate and short terms concerns, animal welfare problems are an ongoing concern throughout the world and may be more marked as we move out of the current crisis and into the new normal. One example - given economics and financial expenditures for the pandemic, many (most?) non-profits will be challenged in the near future with reduced funds and donations. And, will animal welfare programs suffer with the focus on the problems of people? We must work to be sure that does not happen. And, as has been discussed in other blogs, What about the dogs?!? Ian does a great job describing possible impacts on the dogs, themselves. I would add that online training courses are great, but without the opportunity for e.g. puppy classes, dogs might not get the socialization with others of their own kind. One of our IPFD consultants is concerned about similar issues with her 19-month-old toddler - surrounded by adults but deprived of play opportunities with other children. (We feel he may be fine however, as his best friend is their Corgi, who is likely an excellent surrogate for other kids!) Then, as Ian suggests, perhaps being overly-socialized (my term) with people - receiving 24/7 attention now - what happens when that suddenly stops? Ian's main point is unintended consequences - and I might add that in times of stress, urgency, and uncertainty there is likely an increased tendency for impulsive vs. well-considered decisions - about many things, including breeding or acquiring a dog. At IPFD, everything we do reminds us of the inter-connectedness of issues of health and welfare, the role of human-dog interactions, and the roles and contributions of many stakeholders. And everything we do, DogWellNet.com, International Dog Health Workshops, my blogs, etc. tries to remind us of the big picture. As Ian suggests, models are great - but! As an epidemiologist, I have been asked about this frequently lately. And this is the reality: Models are only as good as the data and assumptions on which they are founded. Even with great inputs models inherently output predictions not certainties which should be expressed as such, with ranges ('error' in statistical terms) and as best-case/ worst-case scenarios, never exact proclamations. In the case of the novel (i.e. new to us) coronavirus there are vast unknowns, and therefore the uncertainties for models and decision making are huge. Ian ends with: "There are unanticipated consequences of any decision, but my glass is always half-full and I am optimistic that we will come out of this situation stronger as a dog community. Remember: DOGS ARE FOR LIFE, not just for Coronavirus." And that last bit I started with as the title of this blog. Another blog is scheduled to cover the impacts in the veterinary world... including the constantly and quickly evolving world of veterinary regulations in the face of COVID-19, including the expanded possibilities or 'telemedicine'. Let' follow Ian's lead, and try to think about the glass being half-full, look for creative ways to remain positive, and move forward with compassion for all. After note: Since posting this blog, another article has come to my attention. "I Got a Pandemic Puppy, and You Can Too" in The Atlantic. This article is full of wonderful reasons why a dog is a great support and benefit to humans. And does caution, "as long as new owners act intentionally and with long-term planning in mind, the prolonged stretch of time at home might provide a unique chance for owners to bond with new pets." My concern is whether most people, in the rush to satisfy their short term needs, have really planned explicitly for those long term challenges or just think they can figure all that out down the road. And heaven forbid we start a trend where having a 'Pandemic Puppy' becomes a status thing. The authors go on to say, "This difficult period may mean that people become more attached and attuned to their pets than if they were seeing their animals for only a few hours a day, which may help get them through the hurdles of pet ownership with slightly less frustration." Indeed, and yet presumably people will transition rather easily to going back to work and adjust to less time with their dog. As mentioned it the blog above and the other we have cited... how easy will it be for the dog? Remember - that bond goes both ways. Will we have shelters getting inundated with 'Pandemic Puppies' with separation anxiety when their owners return to their busy lives? More unintended consequences? Also pertinent to the discussion above, and with absolutely no reference to specific sources mentioned to the article in The Atlantic, if a retail source can markedly and quickly increase the number of puppies available in response to Covid demand - I would want to carefully determine from where those animals came. Glass half full again - let's hope we end up with more committed, responsible dog owners and well-adjusted healthy dogs in good situations. Let's hope. .
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"When 23 and Me Has Gone to the Dogs" - Balancing Challenges and Benefits
Brenda Bonnett posted a blog entry in Brenda's Blog
An article in The Canine Chronicle October, 2019, by Caroline Coile, is entitled: When 23 and Me Has Gone to the Dogs. PDF-Reprint version It is a summary of some of the discussions and presentations at the 2019 AKC CHF National Parent Club Canine Health Conference. I have already written a blog on my experiences speaking and participating at that meeting: AKC-CHF SYMPOSIUM: Harmonization of Genetic Testing and Breed-Specific Resources, where I cover some of the same ground at Ms. Coile. In that blog, I described the challenges voiced by breed club health committee reps, reflected in the questions they asked during the panel discussions. I said, for example: "It is not surprising that you are confused and frustrated...the world of genetic testing IS confusing and frustrating!" The worst challenges in communication and understanding have arisen, at least to some extent, by a combination of these factors: A very fast progression from hesitancy to mass acceptance of genetic testing as the ultimate measure of health and disease to inform breeding decisions. Driven by, e.g.: The 'Social Phenomena' and marketing of tests Direct-to-Consumer (see my talk at the American Veterinary Association). The underlying desire for absolute, straight-forward, black-and-white, simple answers to complex situations. And hampered by, e.g.: Lack of the full, key information for properly integrating genetic testing into best breeding practices. This lack due to, e.g.: Overemphasis of research on discovery of new genetic associations compared to study of clinical validity and ultimate utility of genetic tests relative to actual disease occurrence in the populations to which they will be applied. Rapid commercialization and offering of tests without anywhere near the level of validation and assessment of quality that is demanded for genetic tests in the human sphere and for virtually all other sorts of tests used in veterinary medicine. Inadequate availability of informed genetic counseling - with the genetic counselors challenged by the situations described above. Many genetic test providers providing full results on the plethora of tests and trusting consumers to be able to access counseling and/or figure it out themselves. An important aspect of this emphasis on genetic testing, mentioned in the Coile article is that, with this rush to genetic testing, there is a tendency to ignore or reduce the emphasis on the big picture of health in a breed, and to sometimes abandon or neglect health strategies and breeding decisions based on them. This I discuss in basically all my talks, e.g., in a presentation to the French Bull Dog Club of America in 2018. So - challenges, challenges, challenges - for genetic testing from research to application and from validity and quality issues to understanding and communication of best practices for all stakeholders and consumers. However, let's not 'throw the baby out with the bathwater'. Genetic testing has already supported health and breeding decisions, especially for simple recessive, fully-penetrant conditions. Unfortunately, these are the 'low-hanging fruit' for scientific discovery, and much attention has been paid to them. They are often rare conditions, and although detection and health strategies for them are very important to the limited number of dogs/lines affected, they may not be the most important conditions for the breed. The most common and important conditions, as also stated in the Coile article, are much more complex. Great things are possible with genetic testing. Whole genome analysis will offer even more potential to help animals and people. However, it looks like genomic testing will also be implemented in spite of great gaps in our understanding of what it means and how to apply it. This video from the human side offers some startling information that should increase our concern (see Strategic Planning Workshop: Genomics in Medicine). It is important to also focus on the good work being done to support stakeholders in dog health. Coile mentions the OFA and AKC-CHF is busy with many endeavours (including supporting IPFD). A great example is the Webinar by Joan Coates tomorrow (Thursday 16 October) on the topic of the hour - DM. Dr. Coates' comments at the Parent Club Symposium were important and it is great that they are being expanded to a Webinar. It is expected that she will clarify the DM-testing benefits and challenges, but we cannot kid ourselves that it can rectify the already-entrenched attitudes about DM in specific and genetic testing in general among the public. Hope is also offered by the existing and continuing developments by IPFD, on DogWellNet.com, and produced in collaboration of a wide network of international collaborators, although dependent on funding and further support. These include (and see my CHF talk): The Harmonization of Genetic Testing for Dogs (HGTD) - catalog on genetic test providers (GTPs) and tests (see the HGTD on DogWellNet.com). Initiative to clarify which tests are being offered specifically as targeted, relevant for a breed; collating information on benefits and challenges of panel testing vs. a breed-specific approach. Working Groups from the 4th International Dog Health Workshop (see article on post workshop genetics theme) on: A comprehensive matrix of the test discovery-commercialization-application pathway . Details on criteria need to provide validation at each step. Aspects of laboratory quality and best practices for GTPs. The potential for enhanced Proficiency Testing. Development of an Expert Panel application to assess and provide collective opinion on key issues about tests and testing. The Big Picture: developing the Heath Strategies Database for Dogs (HSDD), that will provide an interactive resource by breed and condition for all diseases/conditions considered important in health strategies from international and local kennel clubs and breed organizations, to include but not be limited those for which a genetic test is available. A structure for an Globally Relevant International Health Profile to summarize the state of health for breeds. Working together, we can improve our ability to make the best decisions for dogs and capitalize on the potential tools and strategies available. -
DogWellNet Digest: Issue #29 - 18 February 2020
Dave St. Louis posted a article in DogWellNet.com Digest
News & Highlights Every Step We Take... Make a Donation Stay Informed! -
As many of you may know, there has been a lot of focus of health and welfare issues in brachycephalics and in the spring information about Pugs in the Netherlands. The situation of government regulations on dog breeding is a complex one, and without appropriate inclusion of all relevant stakeholders, we cannot be sure that the best interests of dogs will be served. Our partners the Dutch Kennel Club have been working intensely with various groups and have come out with their thoughtful and evidence-based recommendations in the attached breeding strategy document. Thanks to veterinarian Laura Roest for sending us this communication. Dear reader, Enclosed you find the translated proposal the Dutch Kennel Club ‘Raad van Beheer’ has sent to the Dutch Government. This is not a certified translation, but gives us the opportunity to inform the international community. Please feel free to ask questions regarding the document. In March 2019, the report “BREEDING BRACHYCEPHALIC DOGS*" was published in The Netherlands (in Dutch) with enforcement criteria for the breeding of brachycephalic dogs. These criteria were active from that day onwards. The Raad van Beheer concurs with almost all criteria and wishes to adapt them in its own regulations, in close collaboration with the involved breed clubs. The Raad van Beheer does not agree with the Craniofacial Ratio (CFR) as a prohibiting criterion for breeding. This criterion would make it impossible to breed certain breeds while the prognostic value and the reproducibility of the CFR are being questioned among scientists. The Raad van Beheer wants an exception for the regulated pedigree breeding, so these breeds can be bred in The Netherlands in a healthy form and with the effort to achieve a longer muzzle. We hope to receive soon a positive reaction on our proposal from our Government and we will keep the International Dog World posted! Kind regards, Laura Roest, DVM and Gabri Kolster Board Member Raad van Beheer Breeding Commission Dutch Kennel Club ‘Raad van Beheer’ Translated version: English... Breeding strategy brachycephalic dogs in the Netherlands.pdf Also see: background articles/resources: Stricter rules for breeding brachy dogs https://dogzine.eu/en/newsarticle/stricter-rules-breeding-brachy-dogs *FOKKEN MET KORTSNUITIGE HONDEN (Dutch) Fokken_met_kortsnuitige_honden_.pdf Utrecht University posted an article in January 2019... Criteria for breeding healthy short-nosed dogs https://www.uu.nl/en/background/criteria-for-breeding-healthy-short-nosed-dogs "New animal welfare criteria The report Fokken met kortsnuitige honden ["Breeding with short-nosed dogs"] by the Expertise Centre Genetics of Companion Animals outlines a limited number of enforcement criteria and describes numerous additional criteria that can further help vets and breeders to select for healthy parent animals. The report is available Dutch and has been translated into English and German." Internal English - eng_breeding_short-muzzled_dogs_in_the_netherlands_expertisecentre_genetics_of_companionanimals_2019_translation_from_dutch.pdf Internal German de_zuchten_mit_kurzschnauzigen_hunden_-_kriterien_zur_durchsetzing_-_ubersetzung_aus_dem_niederlandischen.pdf
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Congratulations to our Partners and Collaborators at Société Centrale Canine (SCC)- The French Kennel Club. Having had the privilege to visit their offices and their amazing library, many times, I am happy today to share links to their wonderful online library of images. (Note: the images here are screen captures... the actual images online of even higher quality.) See La Photothéque Old and new.... dog shows, events, military history, cultural treasures, dog breeds... and more. The catalogs include thousands of images which can be purchased. Just browsing through them will remind you of the diversity of ways in which we interact with dogs... ways in which they enrich our lives. In the face of criticism of purebred dogs a collection like this can serve to educate others and remind us that the world of purebred dogs involves so much more than conformation dog shows. These still images enforce the the link between form and function - especially in categories like "Contest of Use" which includes e.g. water rescue, tracking, utility search, and more. Thank you to the SCC for sharing this wonderful resource! Championnat de France de chiens de sauvetage en mer 2012
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Another interesting post from our IPFD friend and collaborator and Dachshund Breed Health Council Coordinator Ian Seath. Following his insightful discussion about puppy socialization that was prompted by reports of increased numbers of mini-dachs [(see here)] he has provided a classification of breeders to help define sources of puppies (see: Breeders, the good, the bad and the future). I think it is important emphasize his message and to add a few further comments. As was discussed in our Supply and Demand theme at the 2019 International Dog Health Workshop - the issues surrounding why, how and from where consumers acquire puppies is a complex issue. Although Ian's categories are very helpful to educate those buying pets, the further complication is that there are better and worse sources within each category of breeder, and there are no guarantees of overall quality, welfare, socialization or short or long term health based simply on the type of breeder. We can likely assume a higher probability of a good 'product' from some categories, but it is not a 'given'. And unfortunately, depending on country, region, licensing requirements and, most importantly, enforcement of any regulations there are few sources of information on specific breeders for prospective buyers. I am reminded here of our challenges in deciding what is the most important health issue in a breed, i.e., the most common? the most severe? the one that is most topical on social media? the one that seems to be affecting MY dogs? And how we have tried to use ranking systems. e.g. GSID, but challenges remain. We need to consider breeders from several angles; not only on volume of puppies produced, but also on, e.g.: Quality of the whelping and puppy-rearing environment. I have seen some commercial breeders with phenomenal facilities and puppies in 'the home' in deplorable conditions. Socialization - same thing; producing just one litter at a time does not guarantee that puppies will be well-adjusted to other dogs or people. Attention to good breeding practices - e.g. health testing, genetic testing, consideration of impact on the breed (e.g. use of Coefficients of Inbreeding). And these are just a few examples but they underline that it is the actual circumstances for each puppy that are important... which may not be reflected in a description of the breeder, per se or their operation. I have to also point out the probability of a safe and successful acquisition is also variable when getting a dog from a 'shelter' or 'rescue' organization. As discussed previously, [see DHW Supply & Demand resources] unfortunately, among the groups sourcing re-homed pets are both bonafide and questionable/ unknown or downright dodgy suppliers. There are many doubtful groups that have jumped in to supply the internet-fueled demand for rescues over primary-sourced dogs - even though it has been shown that there are groups buying dogs from large commercial breeders and puppy farms and re-selling them as 'rescues'. It is very difficult to distinguish the well-meaning from those out for commercial gain. And, sadly, just as for breeders, being 'well-meaning' is not enough to ensure health and welfare of the dogs on offer. So for now, we can try to educate with articles like Ian's, and perhaps lobby for better oversight, but the phenomenal demand that is driving the problem is unlikely to change soon. In fact, consumers also may be 'well-meaning' in terms of intending to carefully research what pet suits their situation and to carefully screen the source...but then succumb to their desire for the trending pet of the moment and wanting what they want right now. Kennel clubs may also have shied away from regulations, as, there being such a difficulty in defining a 'good breeder', most proposed regulations may be seen as a threat to their members. The most important thing is to keep this topic front-and-center in all discussions of dog health, well-being and welfare. And - work across stakeholder groups and internationally for solutions. We look to many of our working groups identified at the 4th IDHW to help us advance... Thanks Ian! See additional information: Detailed Discussion of Dog Auctions and Retail Rescue