Border Collie
Border Collie
FCI Group
Sheepdogs and Cattledogs (except Swiss Cattledogs)
AKC Group
Herding
TKC Group
Pastoral
Country of Origin
GB
Border Collie
Health Testing Requirements by Country
Skin, Hair, and Nails
FI
Ear, Deafness
Skeletal and Muscular
UK
Ataxia, Locomotor, and Epilepsy
SE
Eye Conditions and Blindness
Neurological and Neuromuscular
Temperament
Other Genetic Testing
Test Relevances
Neuropathy, Sensory
Strong Relevance
Goniodysgenesis and Glaucoma Susceptibility
Moderate Relevance
Hyperuricosuria and Hyperuricemia (HUU)
Moderate Relevance
Multidrug Resistance 1 (MDR1)
Moderate Relevance
Canine Cyclic Neutropenia (Grey Collie Syndrome)
Some Relevance
Collie Eye Anomaly (CEA/CH)
Some Relevance
Degenerative Myelopathy
Some Relevance
Dental Hypomineralization
Some Relevance
Progressive Retinal Atrophy rcd2 (PRA-rcd2)
Some Relevance
Imerslund-Grasbeck Syndrome (I-GS), CUBN related
Some Relevance
Neuronal Ceroid Lipofuscinosis 5 (NCL5)
Some Relevance
Primary Lens Luxation (PLL)
Some Relevance
Trapped Neutrophil Syndrome (TNS)
Some Relevance
Breed/Type/Variety Identification
No Evidence
Coat Colour Dilution, dilution, MLPH-related
No Evidence
Dermatomyositis
No Evidence
Hair, Long
No Evidence
Pyruvate Kinase Deficiency
No Evidence
Von Willebrand Disease I
No Evidence
Von Willebrand Disease II
No Evidence
Myotonia Congenita
No Evidence
Neuropathy, Sensory
Strong Relevance
Goniodysgenesis and Glaucoma Susceptibility
Moderate Relevance
Hyperuricosuria and Hyperuricemia (HUU)
Moderate Relevance
Multidrug Resistance 1 (MDR1)
Moderate Relevance
Canine Cyclic Neutropenia (Grey Collie Syndrome)
Some Relevance
Collie Eye Anomaly (CEA/CH)
Some Relevance
May be relevant across many breeds, including those not specified in the literature, but of shared origins. Several reports have been raised that in some breeds the causality of the mutation may be complex. Clinical diagnosis may be especially important to the individual dog.
Degenerative Myelopathy
Some Relevance
Both clinically rare and of complex inheritance. Test is considered poorly correlated with risk for development of DM, and recommendations are to not use the test for breed-wide breeding strategies, even where there is some evidence of the presence of DM in the breed. While the SOD 1 variant may be commonly found across many breeds, there are few clinical cases observed and confirmed, and in many cases DM has never been observed in the breeds.
Dental Hypomineralization
Some Relevance
Progressive Retinal Atrophy rcd2 (PRA-rcd2)
Some Relevance
Imerslund-Grasbeck Syndrome (I-GS), CUBN related
Some Relevance
Neuronal Ceroid Lipofuscinosis 5 (NCL5)
Some Relevance
Primary Lens Luxation (PLL)
Some Relevance
Findings indicate the mutation segregates in a large number of different breeds of dog, many of which are terriers or breeds with terrier co?ancestry, but some of which have more diverse origins. Research indicates that the mutation is present at high frequency within most of the breeds in which it segregates. (Gould et. al, 2011)
Trapped Neutrophil Syndrome (TNS)
Some Relevance
Breed/Type/Variety Identification
No Evidence
Coat Colour Dilution, dilution, MLPH-related
No Evidence
Dermatomyositis
No Evidence
May be relevant, as mutation and phenotype identified in closely related breeds
Hair, Long
No Evidence
Hair length testing has the potential relevance to any dog, but test usage is most often applied to those breeds with a heritage of these traits.
Pyruvate Kinase Deficiency
No Evidence
Von Willebrand Disease I
No Evidence
Mutation is widespred, so may be relevant
Von Willebrand Disease II
No Evidence
Myotonia Congenita
No Evidence
Connections
- Updated