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Primary Open Angle Glaucoma (POAG) ADAMTS10
Primary Open Angle Glaucoma (POAG) ADAMTS10
  Discussion

Primary open angle glaucoma, also known as POAG, is a painful condition where the pressure in the eye(s) increases over time eventually leading to blindness.

Breed-specific research: Beagle, Norwegian Elkhound

  Genetics
Inheritance
AR
OMIA
001870
OMIA Variant
000043
OMIA URL
https://omia.org/OMIA001870/9615/
OMIN
137760
Gene
ADAMTS10
Variants
g.53096339C>T; c.1981G>A; p.(G661R); XM_849227.3; XP_854320.1; g.53101896G>A; c.del2986_2991
Variants Comments
ADAM metallopeptidase with thrombospondin type 1 motif, 10
  Testing
Test Types
Genetic-Genomic
Assessments
Eye / Ophthalmologist Exam
Specific Genetic Test
Assays
Direct Mutation
Connections
A Novel Missense Mutation in ADAMTS10 in Norwegian Elkhound Primary Glaucoma
Reference - Journal Article
Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma.
Reference - Journal Article
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