Cleft Palate
A cleft palate is an abnormal opening in the roof of the mouth. It is the result of failure of the two sides of the palate (roof of the mouth) to come together and fuse during embryonic development.
Discussion
A cleft palate results in an opening between the nasal passages and the mouth. Symptoms expected with a cleft palate include: runny nose, coughing, aspiration pneumonia (pneumonia caused by milk and food contents entering the cleft and infecting the lungs), respiratory difficulty (caused by aspiration pneumonia), difficulty sucking and nursing (for puppies), slow growth, weight loss, lack of appetite. Cleft palates can be inherited, and also have non-inherited causes, such as environmental effects - i.e. vitamin deficencies.
Genetics
Inheritance
AR
OMIA
001919
OMIA Variant
000728
OMIA URL
https://www.omia.org/OMIA001919/9615/
OMIN
261800
Gene
DLX6
Variants
cfa14.25016716ins2056bp L1
Variants Comments
Testing
Test Types
Genetic-Genomic
Assessments
Specific Genetic Test
Assays
Direct Mutation
Connections
- Updated
- Add Condition