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International Partnership for Dogs - Enhancing Dog Health, Well-Being, and Welfare - Join Us
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About This File

Oculoskeletal dysplasia

Canine genetics research at the Animal Health Trust
• Basic genetics
• Finding disease mutations
• Genetics of OSD – Part 1 –
        Identifying the causal mutation
• Genetics of OSD – Part 2 –
       Implications for the breed
• Summary and Breeding Advice
• Acknowledgements
• OSD3 DNA Test

Breeds information/impacts...

- the drd1 mutation in the gene COL9A3 in the Labrador retriever
- the drd2 mutation in the gene COL9A2 in the Samoyed - autosomal recessive mode of inheritance of the complete phenotype

• Clinical findings in the Labrador retriever & in the Samoyed
  (Carrig et al. 1988 & Goldstein et al. 2010)
- disproportionate dwarfism
- corneal opacities, cataracts, persistent hyaloid artery remnants, vitreal dysplasia, alterations in optic nerve head colour + size, retinal dysplasia retinal detachment
• Recently observed in 7 Northern Inuit Dogs (NID)

 


  • International Dog Health Workshops

    Decision leaders from major stakeholders moving from information to action.

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    Post-Meeting Resources
    Plenary talks, Posters & outcomes

  • Our Partners

    • Headquartered in Denver, Colorado, Morris Animal Foundation is the largest nonprofit foundation in the world dedicated to funding studies to improve and protect the health of companion animals and wildlife. Since its establishment in 1948, the Foundation has invested $126 million toward more than 2,600 studies that have led to significant breakthroughs in disease, toxic exposures and injury diagnostics, treatments and preventions to benefit animals worldwide.  
    • Our mission is to safeguard the health and wellbeing of your pet with fully personalised, breed-specific care. Orivet was founded on the premise that each and every pet is unique, with its own set of specific traits, behaviours, genetic health needs and inherent risks. We work with pet owners, breeders and vets to provide completely personalised products and services that treat and care for pets as the unique individuals they are, taking into account each pet’s genetic makeup, age, sex and lifestyle.   Through this we aim to encourage the development of a deep, genuine and lasting bond between pets and their owners.   Orivet is a proud sponsor of IPFD's Harmonizatio
    • IPFD is truly a "people driven" service organization. We allocate the bulk of our financial resources to maintain a small but dedicated team of consultants to manage our modest resources and facilitate the activities of our stakeholders, with the aim of achieving our collective goals.   Your generous donation to support IPFD and its programs helps ensure our long-term sustainability and supports ongoing efforts to create an enduring global collaboration that enhances the health, well-being, and welfare of all dogs worldwide.             By supporting the Harmonization of Genetic Testing for Dogs initiative you can help us impro
    • The Canadian Kennel Club (CKC) is the primary registry body for purebred dogs in Canada and currently recognizes 175 breeds. As a non-profit organization, the CKC is dedicated to encouraging, guiding, and advancing the interests of purebred dogs and their responsible owners and breeders in Canada and promoting the knowledge and understanding of the benefits which dogs can bring to Canadian society.  
    • A Continuing and Sustainable Development The International Partnership for Dogs (IPFD) and DogWellNet.com have come into being following a long history of efforts by many stakeholders to address dog health and well-being. An abbreviated timeline of key developments will highlight the complexity of issues addressed by the IPFD and DogWellNet and will list some of the many supporters and collaborators that have contributed directly or indirectly to this important work. Development was inaugurated under the patronage of the Fédération Cynologique Internationale (FCI). The major contributors (in-kind and funding) since 2011 have been, chronologically, the Agria Animal Insurance
    • The Kennel Club is the largest organization in the UK devoted to dog health, welfare and training. Its objective is to ensure that dogs live healthy, happy lives with responsible owners.   Website: http://www.thekennelclub.org.uk  
    • The VDH - Verband für das Deutsche Hundewesen (German Kennel Club in English) is the foremost organisation representing the interests of dog owners throughout Germany – the first address to find out everything there is to know on the subject of life with dogs, on dog sports and on dog breeding. As an umbrella organisation for its 175 member clubs, the VDH today represents more than 650,000 members.   Website: http://www.vdh.de/en/home/ Registration Statistics: https://www.vdh.de/ueber-den-vdh/welpenstatistik/ An overview of the VDH (in German) can be found here.    "The VDH is the leading advocacy of all dog owners in Germany - the primary authority on life with d
    • IPFD logos, annual reports, and other resources for use by the media are available here.
    • The Veterinary Genetics Laboratory (VGL) at the University of California, Davis provides dog DNA testing services, including forensic genetic analyses, to a world-wide clientele. Validation and standardization of genetic tests across laboratories are areas in which the VGL has been engaged in for many years, primarily via workshops supported by the International Society for Animal Genetics.     The VGL is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • We're Genoscoper - the specialists in canine genetics and animal DNA testing. We offer solutions to help you make informed decisions about pet care and breeding, through comprehensive testing services and improved DNA diagnostics, with the most advanced BioIT.     Genoscoper is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • CAG GmbH makes it easy to secure the genetic health of your four-legged friends. We provide the tools you need: a comprehensive offering of genetic tests, quick turn-around in the in-house accredited laboratory, and personal counseling to help you understand what the results really mean for you and your animal. With state-of-the-art technology, a robust R&D program, and dedicated specialists in animal genetics, CAG works with you to ensure the health and happiness of your best friend.     CAG GmbH is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.          
    • Sentinel Biomedical is a pioneering comparative health company committed to research and scientific innovation. The company’s primary focus is investigating canine cancers and identifying biological changes and environmental influences that may be shared with human cancers, making canines true watchdogs in the area of human health.   Sentinel Biomedical is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • See a selection of Press articles related to IPFD's Harmonization of Genetic Testing HERE.
    • IPFD has endorsed the Global Pet Obesity Initiative Position Statement, joining 24 International Veterinary Professional Organizations, including the American Veterinary Medical Association Board of Directors, British Small Animal Veterinary Association, Canadian Veterinary Medical Association, World Small Animal Veterinary Association, and others.
    • The French Kennel Club - SOCIÉTÉ CENTRALE CANINE (SCC) - was founded in 1881 as a non-profit organization by dog fanciers aiming to replenish native dog breeds and to bring in and establish foreign ones as well. The Société Centrale Canine became soon the reference canine organization, being recognized as a public interest organization by decree of the Council of State in April 1914. The SCC is proud to be one of the founders of the FCI in 1911, together with the Kennel Clubs from Germany, Austria, Belgium and the Netherlands.   Website: https://www.centrale-canine.fr/ Follow this link for the French Kennel Club Blog at DogWellNet
    • This year has been challenging for all organizations globally.  However, IPFD has fared well.  We have always been a ‘virtual’-based operation, with all consultants working from home.  Building on our 2019 Annual Report: A Growing Voice, this milestones document is meant to update our Partners and Sponsors on our activities in 2020. – Dr. Brenda Bonnett, CEO (click to download/share as a PDF): IPFD Milestones December 2020.pdf   Message from the Canadian Kennel Club: “CKC’s membership in the International Partnership for Dogs, and participation in the biennial Dog Health Workshop and the international working group for extremes in conformation has strengthened
    • Raad van Beheer (The Dutch Kennel Club (DKC)) is the official kennel club of The Netherlands. Founded in 1902, it currently represents around 200 breed clubs with 150,000 members.   Raad van Beheer is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • FECAVA is the platform for the promotion of professional development and the representation of companion animal veterinarians in Europe. FECAVA strives to improve the veterinary care of pets, to highlight the human-animal bond and the ‘One Health’ concept. It does this through professional development and liaisons with relevant organisations and stakeholders and by facilitating the interaction between European companion animal veterinarians.
    • The World Small Animal Veterinary Association (WSAVA) is an association of associations. Its membership is made up of veterinary organisations from all over the world, which are concerned with companion animals.     The Hereditary Diseases Committee of the WSAVA is collaborating on the IPFD Harmonization of Genetic Testing for Dogs initiative.   Website: www.wsava.org    
    • Agria is one of the world’s leading animal insurers, specialising in small animal and equine insurance. Founded in Sweden over 120 years ago, Agria came to the UK in 2009 and is now a prominent feature of the UK pet insurance industry. In the UK, Agria insures cats, dogs and rabbits.
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