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Comparative analyses of genetic trends and prospects for selection against hip and elbow dysplasia in 15 UK dog breeds


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Authors: Thomas W Lewis, Sarah C Blott and John A Woolliams

 

excerpts from the abstract...

 

"This study aimed to both determine recent genetic trends in hip and elbow dysplasia, and evaluate the potential improvements in response to selection that publication of EBV for such diseases would provide, across a wide range of pure-bred dog breeds."

 

"EBV are shown to be both more accurate and abundant than phenotype, providing more reliable information on the genetic risk of disease for a greater proportion of the population. Because the accuracy ofselection is directly related to genetic progress, use of EBV can be expected to benefit selection for the improvement of canine health and welfare. Public availability of EBV for hip score for the fifteen breeds included inthis study will provide information on the genetic risk of disease in nearly a third of all dogs annually registered by the UK Kennel Club, with in excess of a quarter having an EBV for elbow score as well."

 

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    • VetCompass shares and analyses veterinary clinical information to understand the disorders and improve the welfare of companion animals. Effective systems for the generation, sharing and application of reliable evidence are critical to improve the health of dogs. VetCompass is delighted to formally support and collaborate with the IPFD and DogWellNet which are critical elements in the international effort to better understand and enhance the lives of dogs worldwide.
    • The World Small Animal Veterinary Association (WSAVA) is an association of associations. Its membership is made up of veterinary organisations from all over the world, which are concerned with companion animals.     The Hereditary Diseases Committee of the WSAVA is collaborating on the IPFD Harmonization of Genetic Testing for Dogs initiative.   Website: www.wsava.org    
    • Embark is more than a product, or even a company. It is a promise to share the journey of a lifetime with you and your dog. You invite us, via our app and website, into your home to help you understand and care for your dog like never before. We invite you to join us in making new discoveries in dog health, wellness, care, and understanding: via our research questions, regular results updates, blog posts, social media, and events.     Embark is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • The European School for Advanced Veterinary Studies (ESAVS) is a non for profit organization registered in Luxemburg dedicated to the advancement of veterinary medicine for companion animals. ESAVS was founded in 1991 as a project in the frame of the European Union‘s COMETT II and LEONARDO DA VINCI programs. It is affiliated with the Faculty of Science, Technology and Communication at the University of Luxembourg.  
    • Website: http://www.akc.org
    • At Paw Print Genetics, our geneticists and veterinarians are committed to provide you and your dog unparalleled service with our large menu of tests, online account management and the highest accuracy in the industry.   Paw Print Genetics is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs initiative.        
    • Vetstream Ltd  (www.vetlexicon.com/) offers TLC for veterinary practices so they can provide TLC for their clients and their companion and production animals.   Vetstream is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.    
    • Mission Facilitate collaboration and sharing of resources to enhance the health, well-being and welfare of pedigree dogs and all dogs worldwide. Vision An enduring global collaboration enhancing dog health, well-being and welfare, and human-dog interactions. Values Dog health, well-being and welfare and human-dog interactions contribute to the quality of life for both species. The world is a better place because we share it with dogs. Dog issues are important around the globe and international sharing and cooperation is needed. Goals The general goals of the IPFD are to:  Enhance the health, well-being and welfare of dogs and enri
    • Our laboratory provides a complete testing service for veterinary surgeons to meet the diagnostic needs of your practice.     LABOKLIN is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • "ASHGI is dedicated to the increase and diffusion of knowledge of genetics in the Australian Shepherd, and the inherited diseases from which it sometimes suffers. We envision serving all Aussies, no matter what their purpose, the goals of their owners, or where they live. ASHGI will work both independently and in cooperation with researchers, breed clubs, canine health organizations and foundations that provide grant funds for canine genetics research."  
    • FECAVA is the platform for the promotion of professional development and the representation of companion animal veterinarians in Europe. FECAVA strives to improve the veterinary care of pets, to highlight the human-animal bond and the ‘One Health’ concept. It does this through professional development and liaisons with relevant organisations and stakeholders and by facilitating the interaction between European companion animal veterinarians.
    • Our mission is to safeguard the health and wellbeing of your pet with fully personalised, breed-specific care. Orivet was founded on the premise that each and every pet is unique, with its own set of specific traits, behaviours, genetic health needs and inherent risks. We work with pet owners, breeders and vets to provide completely personalised products and services that treat and care for pets as the unique individuals they are, taking into account each pet’s genetic makeup, age, sex and lifestyle.   Through this we aim to encourage the development of a deep, genuine and lasting bond between pets and their owners.   Orivet is a proud sponsor of IPFD's Harmonizatio
    • ANTAGENE develops, produces and markets DNA tests for parentage certification and disease prevention in dogs and cats. The company is based near Lyon (France) and has a staff of 18 people. ANTAGENE offers more than 100 DNA tests in some 50 countries around the world. ANTAGENE solutions have been used by more than 80,000 breeders and veterinarians the world over.   . ANTAGENE was an initiating sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.    
    • Canine Medicine and Genetics is a peer-reviewed, open access journal addressing genetic, genomic and epidemiological research in both domestic and wild canids, relating to breed and species diversity, and canine evolution.  
    • Online Mendelian Inheritance in Animals (OMIA) is an online database, freely available to anyone in the world, created and curated in the Sydney School of Veterinary Science, within the University of Sydney, by Emeritus Professor Frank Nicholas, assisted by local and international colleagues.
    • A Continuing and Sustainable Development The International Partnership for Dogs (IPFD) and DogWellNet.com have come into being following a long history of efforts by many stakeholders to address dog health and well-being. An abbreviated timeline of key developments will highlight the complexity of issues addressed by the IPFD and DogWellNet and will list some of the many supporters and collaborators that have contributed directly or indirectly to this important work. Development was inaugurated under the patronage of the Fédération Cynologique Internationale (FCI). The major contributors (in-kind and funding) since 2011 have been, chronologically, the Agria Animal Insurance
    • The Kennel Club is the largest organization in the UK devoted to dog health, welfare and training. Its objective is to ensure that dogs live healthy, happy lives with responsible owners.   Website: http://www.thekennelclub.org.uk  
    • Raad van Beheer (The Dutch Kennel Club (DKC)) is the official kennel club of The Netherlands. Founded in 1902, it currently represents around 200 breed clubs with 150,000 members.   Raad van Beheer is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • Around the world many people regard their pets as family members, and we want to help provide the best possible care for them. Screening can help identify the cause of a current problem as well as reduce the risk of future conditions to increase the health of future generations. Animal Genetics offers customers throughout the world a large number of tests for canine hereditary diseases, traits including color and parentage verification.     Animal Genetics is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
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