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Comparative analyses of genetic trends and prospects for selection against hip and elbow dysplasia in 15 UK dog breeds


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Authors: Thomas W Lewis, Sarah C Blott and John A Woolliams

 

excerpts from the abstract...

 

"This study aimed to both determine recent genetic trends in hip and elbow dysplasia, and evaluate the potential improvements in response to selection that publication of EBV for such diseases would provide, across a wide range of pure-bred dog breeds."

 

"EBV are shown to be both more accurate and abundant than phenotype, providing more reliable information on the genetic risk of disease for a greater proportion of the population. Because the accuracy ofselection is directly related to genetic progress, use of EBV can be expected to benefit selection for the improvement of canine health and welfare. Public availability of EBV for hip score for the fifteen breeds included inthis study will provide information on the genetic risk of disease in nearly a third of all dogs annually registered by the UK Kennel Club, with in excess of a quarter having an EBV for elbow score as well."

 

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    • "ASHGI is dedicated to the increase and diffusion of knowledge of genetics in the Australian Shepherd, and the inherited diseases from which it sometimes suffers. We envision serving all Aussies, no matter what their purpose, the goals of their owners, or where they live. ASHGI will work both independently and in cooperation with researchers, breed clubs, canine health organizations and foundations that provide grant funds for canine genetics research."  
    • Reception within the Dog Community   Extensive Outreach: IPFD and DogWellNet.com are being received enthusiastically by the dog community (see examples of media coverage in our IPFD News section), and we are frequently used as a resource and our CEO and other IPFD contributors are approached by partner organizations for veterinary meetings, educational events for breeders and judges, and government and regulatory groups to share international perspectives on tough issues. Recent examples include: Outreach Seminar on Healthy Breeding - 42nd World Small Animal Veterinary Association Congress and 23rd FECAVA Eurocongress  
    • ANTAGENE develops, produces and markets DNA tests for parentage certification and disease prevention in dogs and cats. The company is based near Lyon (France) and has a staff of 18 people. ANTAGENE offers more than 100 DNA tests in some 50 countries around the world. ANTAGENE solutions have been used by more than 80,000 breeders and veterinarians the world over.   . ANTAGENE was an initiating sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.    
    • The Animal Health Trust was a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.        
    • The Veterinary Genetics Laboratory (VGL) at the University of California, Davis provides dog DNA testing services, including forensic genetic analyses, to a world-wide clientele. Validation and standardization of genetic tests across laboratories are areas in which the VGL has been engaged in for many years, primarily via workshops supported by the International Society for Animal Genetics.     The VGL is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • The Kennel Club is the largest organization in the UK devoted to dog health, welfare and training. Its objective is to ensure that dogs live healthy, happy lives with responsible owners.   Website: http://www.thekennelclub.org.uk  
    • A Continuing and Sustainable Development The International Partnership for Dogs (IPFD) and DogWellNet.com have come into being following a long history of efforts by many stakeholders to address dog health and well-being. An abbreviated timeline of key developments will highlight the complexity of issues addressed by the IPFD and DogWellNet and will list some of the many supporters and collaborators that have contributed directly or indirectly to this important work. Development was inaugurated under the patronage of the Fédération Cynologique Internationale (FCI). The major contributors (in-kind and funding) since 2011 have been, chronologically, the Agria Animal Insurance
    • Sentinel Biomedical is a pioneering comparative health company committed to research and scientific innovation. The company’s primary focus is investigating canine cancers and identifying biological changes and environmental influences that may be shared with human cancers, making canines true watchdogs in the area of human health.   Sentinel Biomedical is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • CAG GmbH makes it easy to secure the genetic health of your four-legged friends. We provide the tools you need: a comprehensive offering of genetic tests, quick turn-around in the in-house accredited laboratory, and personal counseling to help you understand what the results really mean for you and your animal. With state-of-the-art technology, a robust R&D program, and dedicated specialists in animal genetics, CAG works with you to ensure the health and happiness of your best friend.     CAG GmbH is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.          
    • Canine Medicine and Genetics is a peer-reviewed, open access journal addressing genetic, genomic and epidemiological research in both domestic and wild canids, relating to breed and species diversity, and canine evolution.  
    • See a selection of Press articles related to IPFD's Harmonization of Genetic Testing HERE.
    • The Norwegian Kennel Club (NKC) was founded in 1898, and is the largest organisation for dog owners in Norway. Website: https://www.nkk.no/english/category1045.html Norwegian Kennel Club Blog at DogWellNet: - under construction -
    • See the September 2016 IPFD Presentation to the Kennel Club's Breed Health Coordinators 2.45 MB · 0 downloads IPFD_Presentation to KC BHCs Sept 2016_post meeting notes_for DWN-web.pdf   Are you involved in a dog club for your breed? Would you like to share information from your kennel club, breed club or country with DogWellNet.com? Already a DogWellNet.com Member?  Sign In, make sure your profile is up-to-date and see Next Steps, below. Visiting us as a guest? Sign Up to participate. Sign Up is open to the public and new participants automatically become  DogWellnet.com Members Members of DogWellNet have access to content including ou
    • VetCompass shares and analyses veterinary clinical information to understand the disorders and improve the welfare of companion animals. Effective systems for the generation, sharing and application of reliable evidence are critical to improve the health of dogs. VetCompass is delighted to formally support and collaborate with the IPFD and DogWellNet which are critical elements in the international effort to better understand and enhance the lives of dogs worldwide.
    • The OFA was a Founding Partner of the International Partnership for Dogs and an Initiating Partner for the HGTD Initiative. See OFA's About Us page at: https://www.ofa.org/about The OFA is a participant in the IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • The French Kennel Club - SOCIÉTÉ CENTRALE CANINE (SCC) - was founded in 1881 as a non-profit organization by dog fanciers aiming to replenish native dog breeds and to bring in and establish foreign ones as well. The Société Centrale Canine became soon the reference canine organization, being recognized as a public interest organization by decree of the Council of State in April 1914. The SCC is proud to be one of the founders of the FCI in 1911, together with the Kennel Clubs from Germany, Austria, Belgium and the Netherlands.   Website: https://www.centrale-canine.fr/ Follow this link for the French Kennel Club Blog at DogWellNet
    • Agria is one of the world’s leading animal insurers, specialising in small animal and equine insurance. Founded in Sweden over 120 years ago, Agria came to the UK in 2009 and is now a prominent feature of the UK pet insurance industry. In the UK, Agria insures cats, dogs and rabbits.
    • We're Genoscoper - the specialists in canine genetics and animal DNA testing. We offer solutions to help you make informed decisions about pet care and breeding, through comprehensive testing services and improved DNA diagnostics, with the most advanced BioIT.     Genoscoper is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • Headquartered in Denver, Colorado, Morris Animal Foundation is the largest nonprofit foundation in the world dedicated to funding studies to improve and protect the health of companion animals and wildlife. Since its establishment in 1948, the Foundation has invested $126 million toward more than 2,600 studies that have led to significant breakthroughs in disease, toxic exposures and injury diagnostics, treatments and preventions to benefit animals worldwide.  
    • Embark is more than a product, or even a company. It is a promise to share the journey of a lifetime with you and your dog. You invite us, via our app and website, into your home to help you understand and care for your dog like never before. We invite you to join us in making new discoveries in dog health, wellness, care, and understanding: via our research questions, regular results updates, blog posts, social media, and events.     Embark is a proud sponsor of IPFD's Harmonization of Genetic Testing for Dogs Initiative.      
    • The SKK - Svenka Kennelklubben (Swedish Kennel Club, in English), is Sweden's largest organisation dedicated to dogs and dog owners. We represent the interests of our 300,000 members – first time dog owners, experienced breeders, hunters, dog lovers, puppy buyers, exhibitors, agility competitors and many more.   Website: http://www.skk.se/en/ Database: Avelsdata Follow this link for the SKK Blog at DogWellNet Follow this link for more information on the Swedish Kennel Club including our organizational structure, code of ethics, and more.
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