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HGTD & Genetic Testing

A group blog by IPFD Genetic Testing Team in General

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About this blog

What's new in the Harmonization of Genetic Testing database and genetic testing resources on IPFD.

Entries in this blog

HGTD & Genetic testing

This week in HGTD: direct variant/mutation, linkage, and risk tests – what are they?

This blog describes common types of individual disease/trait genetic tests. Understanding the principles behind these tests can improve confidence in applying test results to breeding strategies and other decision-making, in conjunction with health experts.    The development of direct to consumer genetic testing means that many veterinarians, canine health advisors, breed and kennel clubs, and individual owners are basing breeding and other health considerations on testing information
HGTD & Genetic testing

HGTD This week: How Breed Relevance Ratings (BRR) are estimated for cross-breeds and ALL dogs

Breed Relevance Ratings (BRR) are a way to assess the relevance of a specific test for a specific breed, based on the currently best-known information on the research and development of a test - but genetic tests are not limited to pedigree breeds. Genetic tests are used for a variety of reasons on all dogs, and understanding the relevance is important for any purpose-bred dog or breeding program, as well as individual dogs. BRR’s are estimated for all dogs, and where the research is not availab
HGTD & Genetic testing

HGTD This Week: What does is mean when a dog is promoted as "genetically tested?"

19 Oct 2020 If you’re a dog owner, or looking for a puppy what does it REALLY mean when a dog is “genetically tested”? “My dog is genetically tested” is an increasingly common statement from dog owners. We see it on breeder’s webpages as part of advertising puppies, or as information on the dam/sire… it’s common on social media as a point of pride or a mark of care and responsibility by owners… but what does genetically tested (or DNA tested) actually mean? While using genetic testi
HGTD & Genetic testing

HGTD This week: Calling all breed experts!

Calling All Breed Experts! HGTD’s phenes database and breed relevancy ratings (BRR) are an important source of information for anyone engaged in dog health and breeding, through the harmonizing of scientific data from a wide-variety of experts, research publications, veterinary and genetics researcher contributions, and in-house expertise.  Just as important, though, are the contributions from breed experts. Breed experts are individuals with significant knowledge of their breed or bre
HGTD & Genetic testing

HGTD This week: Vets - what can HGTD do for you?

Vets – what can HGTD do for you? Genetic testing is part of our dog's lives Just as genetic testing has become normalized in the human world, thanks to popular direct to consumer products like 23 and Me, or Ancestry.com, so it has in the veterinary world. While perhaps once the preserve of specialist dog breeders, it is increasingly common for vets in practice to have questions from clients about DNA testing. While covering the basics of testing and inheritance is part of many veter
HGTD & Genetic testing

HGTD This week, 19 June 2020: NEW Orange Breed Relevance Rating (BRR)

The continued review of breed-specific tests for assigning relevance ratings, and ongoing discussions with genetic experts has led to a refinement of the breed relevance ratings (please see: BRR) . To better accommodate the spectrum of genetic test validation, we’ve added a new orange BRR.  The orange BRR indicates where all current available evidence has been reviewed, but the relevance is inconclusive. It could be that a mutation is detectable in a specific breed, but that there is no evi
HGTD & Genetic testing

HGTD This week, 12 May 2020: more breed-specific information, and more updated BRRs

HGTD Update: 12 May 2020 Since the last blog, we’ve had additional expert review of many Breed Relevance Ratings (BRRs) – particular in commonly tested eye conditions, and ataxias. As we are growing our expert out-reach for input into BRRs, we are pleased to note that there is consensus between experts self-reviewing their tests as well as peer-reviewing each other. This adds reassurance to us that the current BRR estimation of combining what we can learn from research publications, phene d
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