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HGTD & Genetic Testing

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What's new in the Harmonization of Genetic Testing database and genetic testing resources on IPFD.

Entries in this blog

HGTD This Week: What does is mean when a dog is promoted as "genetically tested?"

19 Oct 2020 If you’re a dog owner, or looking for a puppy what does it REALLY mean when a dog is “genetically tested”? “My dog is genetically tested” is an increasingly common statement from dog owners. We see it on breeder’s webpages as part of advertising puppies, or as information on the dam/sire… it’s common on social media as a point of pride or a mark of care and responsibility by owners… but what does genetically tested (or DNA tested) actually mean? While using genetic testi

HGTD This week, 14 August 2020: Vets - what can HGTD do for you?

Vets – what can HGTD do for you? Genetic testing is part of our dog's lives Just as genetic testing has become normalized in the human world, thanks to popular direct to consumer products like 23 and Me, or Ancestry.com, so it has in the veterinary world. While perhaps once the preserve of specialist dog breeders, it is increasingly common for vets in practice to have questions from clients about DNA testing. While covering the basics of testing and inheritance is part of many veter

HGTD This Week, 7 Aug 2020: Canine Crime Scene Investigators

HGTD This Week, 7 Aug 2020: Canine Crime Scene Investigators When we think about genetic testing, we often focus on how it can be a tool to improve health and welfare - generally centered around breeding for health or finding more about the health or potential health risks for an individual dog. Knowing about health risks that are especially relevant to specific breeds or dog types makes testing even more powerful in helping reduce risks of disease or undesirable traits (see Breed Relevancy

HGTD This Week, 15 July 2020: One Disease, 20 Causes? It's All in the Name

The Harmonization of Genetic Testing for Dogs (HGTD) project work includes harmonizing genetic test information across many different boundaries. That can be as simple as adding consistency to nomenclature from around the world, or as challenging as cataloging test information and research from dozens of different international sources. With so much variation in how tests are developed, and how they are released to the public, a big part of my work is ensuring that phene names we publish on HGTD

HGTD This week, 19 June 2020: NEW Orange Breed Relevancy Rating (BRR)

The continued review of breed-specific tests for assigning relevancy ratings, and ongoing discussions with genetic experts has led to a refinement of the breed relevancy ratings (please see: BRR) . To better accommodate the spectrum of genetic test validation, we’ve added a new orange BRR.  The orange BRR indicates where all current available evidence has been reviewed, but the relevancy is inconclusive. It could be that a mutation is detectable in a specific breed, but that there is no evi

HGTD This week, 28 May 2020: How OMIA is key to HGTD, and more fantastic phenes

HGTD, and IPFD, were thrilled to be able to send our very best wishes and acknowledgements to Prof Frank Nicholas, on the 25th Anniversary of the Online Mendelian Inheritance in Animals (OMIA) resource. (see Brenda's Blog) Collaboration with, and integration of OMIA's information is vital for a lot of what HGTD is able to do - and fundamental to animal genetics researchers the world over. OMIA is a catalogue/compendium of inherited disorders, other (single-locus) traits, and genes in 251 animal

HGTD This week, 12 May 2020: more breed-specific information, and more updated BRRs

HGTD Update: 12 May 2020 Since the last blog, we’ve had additional expert review of many Breed Relevancy Ratings (BRRs) – particular in commonly tested eye conditions, and ataxias. As we are growing our expert out-reach for input into BRRs, we are pleased to note that there is consensus between experts self-reviewing their tests as well as peer-reviewing each other. This adds reassurance to us that the current BRR estimation of combining what we can learn from research publications, phene d

The HGTD Path to Improving Access to Genetic Testing Information

We get questions about how we ensure the quality of the information available on HGTD. It can actually be very challenging, and we rely on having good processes, and collaboration when developing content. To meet the IPFD principle of transparency, we are starting a series of blogs to describe how we manage this resource. We hope to then provide a regular news feed on HGTD developments and changes, to give you all an insight into this work. To get started, here is a little insight into running a

Harmonization of Genetic Testing (HGTD) 2019 Summary

The HGTD arose from discussions at the IPFD International Dog Health Workshops (IDHWs); it is a proud achievement,  exemplifying the IDHW tagline:  Information – Collaboration – Action! In 2019, the HGTD project could be summarized in one word: Growing. We’ve consistently grown our list of genetic test providers (GTPs). Participating GTPs have provided information on their accreditation, expertise, and practices – all of which helps individuals find a GTP that has the quality measures most
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