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  • Brenda Bonnett

    COVID-19 - a novel experience for dogs and people

    By Brenda Bonnett

    Sources of accurate and relevant COVID-19 information for your dog, your puppies and you. In the face of the great uncertainty surrounding COVID-19 and its impact on pets and pet owners, many veterinary and regulatory organizations have been providing excellent information and advice, as have kennel and breed organizations.  It is important to remember that recommendations and restrictions vary depending on location and owners need to access and follow local recommendations, especially as t
    • 2 comments
    • 2,517 views

Our community blogs

  1. Closed populations and the pursuit of exaggerated traits predispose dog breeds to health and behavioural problems. What should be done in this situation to ensure that pedigree dog breeding can continue in the future and that the reputation of pedigree dogs is enhanced? Some countries have gone the way of breed bans, but in Finland the solutions are different. The Finnish Kennel Club's (FKC) webinar on 21 November 2024 explored what these solutions might mean in practice.

    The webinar was open to everyone, and the panel included Kirsi Sainio (PhD, Associate Professor of Developmental Biology, Chair of the FKC Breeding Committee), Vilma Reunanen (Licentiate in Veterinary Medicine, Veterinary Specialist), and Liisa Lilja-Maula (DVM, Associate Professor of Veterinary Medicine).

     

    Kirsi Sainio hoped legislation would help, but too much regulation is not good

    The webinar started with a presentation by Kirsi Sainio (also a member of IPFD's distinguished Board), who shared some statistics about the number of dogs and dog breeds in different parts of the world. Most dogs in the world are not pedigree dogs. The FCI, the umbrella organisation of the FKC and other member countries' national clubs, has published statistics on the percentage of FCI registered dogs in different countries, and Finland has the highest percentage in Europe (64% in 2022).

    Sainio also went through the dog-related legislation in Finland and gave an overview of the upcoming EU legislation. Finland's current Animal Welfare Act came into force on 1.1.2023. The content of the Act reflects the desire of Finnish society to take preventive care of the welfare of dogs and other animals, rather than just protecting them from suffering. Members of the FKC have also called for the FKC to take more action to improve the welfare of dogs and reduce the incidence of hereditary diseases.

    Finnish Kennel Club - png-01.pngA Contributing Partner of the International Partnership for Dogs, The Finnish Kennel Club (Finnish site) (English site) has approximately 130,000 members, and its breeding database, which is open to all, contains information on approximately 1.5 million dogs. The FKC has a large number of disease tests for breeding purposes, perhaps the most in the world. The number of disease tests carried out each year is increasing, and the FKC, with the help of vets, has recently developed many new tests, the most recent being a screening test for shoulder osteochondrosis and a test for elbow incongruency in short-legged dogs.

    The new Animal Welfare Act in Finland has also introduced an obligation for veterinarians to notify the authorities of hereditary defects and diseases that exclude dogs from breeding. The information will be collected in an official dog register and will be made public. This raises a number of questions, according to Sainio. For example: Which diseases are covered by the obligation to report? Are all diseases and defects equal? Can the information on dogs be transferred to the FKC's breeding database? Will the obligation to report result in dogs being left untreated or treated abroad?

    The FKC fears that dog breeding could spiral out of control if regulation is perceived as too restrictive. There is already evidence of an increase in unregulated breeding and puppy mills of small companion dogs. Swedish Customs has reported a record number of smuggled dogs. The phenomenon can be seen throughout Europe.

    Sainio asked what to do next. Can unhealthy breeds be changed? "Yes, they can," she replied. Do we need to change these breeds? "Yes, we do.". The health and welfare of the dogs really needs to be a priority in breeding. Change requires cooperation and a positive attitude from all parties. Blaming will not help anyone.

     

    Vilma Reunanen went through the exaggerated characteristics of dogs and the health problems they cause

    The next part of the webinar was a presentation by Vilma Reunanen on exaggerated traits in dogs. Reunanen began by saying that every dog deserves a normal physical structure and a healthy mind. A dog should be able to live a species-typical, effortless, and painless life.

    Reunanen went through several exaggerated features of dogs and asked if we are perhaps used to unhealthy structures. The many exaggerations of canine anatomy and their consequences for the welfare of dogs can be seen in veterinary practices. Exaggerated, unhealthy structures can be seen in the dog's spine, limbs, head shape, and size.

    According to Reunanen, one of the things that can be considered excessive is the overuse of popular males in breeding, which leads to inbreeding and the spread of disease genes.

    Too much is also too much when it comes to the temperament of the dogs," says Reunanen. Some dogs have been bred to be too lively and restless, while others have been bred to be too soft and sensitive. Many breeds have a lot of dogs that cannot cope with everyday life, dogs that are very fearful.

    Reunanen herself prefers pedigree dogs because of their predictability. However, breeders and show judges have to admit that some breeds have unhealthy traits, and most breeds have hereditary diseases that need to be tackled more vigorously. Only by recognising this can we breed healthier dogs.

     

    Final debate called for more effective action to promote dog health

    At the end of the webinar, Sainio, Reunanen and Lilja-Maula answered questions from the audience and discussed dog health and ways to make health a priority in breeding.

    They pointed out that many breeds have changed a lot since the breed standards were written. Breeding should aim at the original type and structure of the breed, from which there has been a sometimes very unhealthy divergence over the years.

    Furthermore, the panelists pointed out that each country can influence the breeding and development of its own breeds, whereas breeds "owned" by other countries are more difficult to influence. Finland is responsible for guiding the breeding of its national breeds and setting their breed standards. Its national breeds, the Finnish Spitz, Karelian Beard, Finnish Hound, Finnish Lapponian Dog, and Lapponian Herder have fortunately remained original in their structure and working qualities, and have not developed any extreme traits.

    According to Sainio, Finland is on the right track, but some things are stagnating. She stated there should be more action, and health should really be the number one priority in breeding. She hopes that legislation will provide the impetus for action.

    Fortunately, the Finnish legislature has its feet on the ground, and it seems that no breeding bans, for example, are on the way. A breeding regulation under the Animal Welfare Act is currently awaited to deal with hereditary diseases and extreme traits.

     

    Finland is perhaps the country with the highest number of screened dogs in the world

    The Finnish Animal Welfare Act stipulates that a breeding dog must be healthy and well. Kirsi Sainio pointed out that disease screening is an important tool for breeding healthier dogs. As scientific research provides more information about breed-specific hereditary diseases, the veterinary profession will also develop new screening tests.

    In Finland, dog owners and breed clubs have been very active in participating in various research studies. Many breeds have been involved in studies of hereditary diseases, which has led to the development of tests for these diseases.

    Liisa Lilja-Maula pointed out that the results of screening tests must be used effectively. X-rays alone will not improve hip health in dogs, but the results must be used systematically in the selection of breeding dogs.

     

    Making health and well-being a priority in breeding

    The panelists agreed that the health and well-being of dogs should be a priority in dog ownership and breeding, and that this should not be a source of confrontation among stakeholders. All stakeholders must play their part in maintaining and promoting this.

    It is in the dog's interest to perform well in the task for which it has been bred. A physically and mentally healthy dog is best able to do this.

  2. DNA.jpgWisdom Panel and Embark have new features in their tests that may be of interest to dog breeders and owners:

     

    Wisdom Panel’s new Behaviors feature

    Wisdom Panel Premium test has a new feature called Behaviors. The feature includes these 15 analyses related to dog behavior:

    • Nesting
    • Crossing paws
    • General fear and anxiety
    • Splooting
    • Propensity to gain weight
    • Pointing
    • Avoids getting wet
    • Friendly towards strangers
    • Hesitant toward strangers
    • Anal sacs need expression
    • Reverse sneezing
    • Motion sickness
    • Panting
    • Sleeps on back
    • Separation anxiety

    Behavioral traits are complex, with hundreds of gene variants at play, as well as the environment that further shapes the traits. That is why Wisdom Health's Behaviors feature uses complex statistical models to analyse hundreds of genetic variants, rather than just one, as most disease tests do.

    With this new feature, dog owners will be able to better understand their dogs and help them grow and develop into the most balanced adults possible.

    For example, if a dog has a genetic likelihood of developing separation anxiety, the owner can take proactive steps to help the dog feel calm and confident when left home alone. Or if a dog has a genetic likelihood of being anxious, the owner can focus on socialising the puppy carefully so that the puppy grows up to be as confident and fearless as possible.

    Read more about the Behaviors feature here >>.

     

    New Embark for Breeders Pair Predictor Tool

    Embark has a new, automated Punnett Square calculator called Pair Predictor that helps breeders understand the potential health risks for puppies produced by a particular sire and dam.

    Using Pair Predictor, breeders can compare the genetic health results of a potential sire and dam, which have Embark test results. After choosing the mating, Pair Predictor will show the probabilities of producing at-risk, carrier, and/or clear puppies for each genetic condition.

    In addition to the potential genetic health risks for each litter, Pair Predictor includes the genetic eCOI for a planned litter, and the coat colour predictions for litters. 

    Pair Predictor works with all breeds and all breed mixes.

    Read more about the Pair Predictor here >>

     

    HGTD-logo-10-27-2020-web-png.pngAdditional Genetic Testing Resources

    IPFD's Harmonization of Genetic Testing for Dogs (HGTD) resources include a searchable database of Genetic Test Providers (labs); genetic tests, and tests by breed, along with Genetic Counselling resources.

     

     

  3.  

    Presentation.jpg

    My First IDHW – Well Worth the Wait!
    As the CEO of the International Partnership for Dogs (IPFD), I had the privilege of attending my first International Dog Health Workshop (IDHW), co-hosted by the Finnish Kennel Club in Helsinki, this past June. Having been with IPFD for just over 18 months, I consider this workshop a significant milestone for me personally and for our organization as it showcased our accomplishments and growth since the previous IDHW in 2019 (co-hosted by The Kennel Club in Windsor, UK), despite the challenges of the COVID-19 pandemic.

    The workshop was an incredible opportunity to meet many key contributors to IPFD's success over the past decade. Putting faces to names and engaging with these dedicated individuals in person was profoundly inspiring.

     

     

    Honouring Prominent Contributors

    Pekka.jpgAward.jpgThe Friday night Gala Dinner gave us an opportunity to acknowledge several individuals who have made exceptional contributions to IPFD and the global dog community.

    It was exciting to witness the introduction of the Brenda N. Bonnett Canine Excellence Award and presentations for our first two recipients: Brenda (who was unable to attend due to health issues) and Åke Hedhammar, a long-time champion of canine health and international collaboration (and who was instrumental in the development of the IDHWs a decade ago!).

    I was also delighted to see our very own IPFD Chair, Pekka Olson, recognized as one of the distinguished recipients of the Pro Cane Sano Medal of Merit, presented by the Finnish Kennel Club – a well-deserved honour!

    For many of us in attendance, the awards ceremony served as a wonderful symbolic conclusion to the first 10 years of IPFD’s journey and an emotional call to action for all of us working to improve canine health, welfare, and well-being into the decade ahead.

     

     

    Breakout Sessions: My Observations and Impressions
    Breakout.jpgIt was very encouraging to feel the amazing energy and hear such positive and forward-looking discussions in the breakout sessions rooms! Below, I share some of my notes from the breakout sessions and summary sessions that followed.

    Supply and Demand
    Attendees suggested the need for regular virtual meetings, with IPFD playing a key role in hosting these sessions. This will ensure continuous collaboration and sharing of ideas among stakeholders.

    Breeding for Health and Well-Being
    The attendees in the room were aligned with the following thoughts. Despite the world's diverse legislation, cultures, and societies, dogs remain consistent and universal in their nature and needs. It's imperative to prioritize the well-being and lives of dogs, embodying the essence of being "KOIRAIHMISIÄ" or "dog people", as written on the wall of the library in Helsinki.

    The proposed solutions focus on better education and understanding within the community, leveraging facts and scientific studies. Compliance with existing laws is crucial, especially considering breeds that currently cannot be bred under present conditions.

    Necessary changes should be made to breeds in need or at risk, which requires consensus on the necessity and approach to these changes. Action points include engaging in ongoing discussions to identify and agree on solutions for the challenges faced, promoting scientific knowledge to enhance community awareness and education, evaluating and adapting breeding practices, and fostering agreement on the need for and methods of making necessary changes to certain breeds.

    Big Data
    Participants discussed maintaining a dedicated webpage on DogWellNet.com to collect and annotate scientific papers on specific topics. This resource would include lay summary paragraphs, providing accessible scientific proof that supports various breeding tools, such as Estimated Breeding Values (EBVs). This page would serve as a valuable resource for breeders, offering them scientific backing for their decisions.

    Additionally, participants suggested the creation of an online resource, resembling IPFD’s Genetic Testing Providers (GTP) database, that would list the major datasets held by various stakeholders. For example, the UK Kennel Club's phenotype information on hips, eyes, and elbows, as well as genome-wide data from genetic testing, could be included. This information would be of great interest to owners, breeders, researchers, and others in the Big Data field.

    There was also a proposal to create an EBV Working Group, like the brachycephalic working group formed after the Windsor workshop. This group would investigate the current use of EBVs in dogs, how they could be more effectively utilized, and how to educate breeders on EBVs through short videos.

    Does the Color Matter?
    Attendees suggested a series of webinars to be made available worldwide through DogWellNet.com, covering the history of breeding and experiences with crossbreeding, including best practices and common pitfalls. Moving towards the harmonization of crossbreeding rules was a key topic.

    Barbara Thiel (IPFD Board Member, Germany) will send out a questionnaire to representatives from various countries to gather information on their crossbreeding rules, which will then be summarized and published on DogWellNet.com.

    The UK Kennel Club was encouraged to explore the possibility of an International Cross Breed Project display at Crufts and consider an International Canine Health Award for crossbreeding projects.

     

    Workshop Outcomes and Future Directions
    The discussions and suggestions from the workshop will set the stage for IPFD's second decade. We’re now taking the initial steps to turn these excellent ideas into tangible international actions. Stay tuned for updates!

    The enthusiasm and collaborative spirit displayed at the workshop underscore the importance of our mission and the impact we can achieve together. I’m excited about the future of IPFD and look forward to working with all our partners and stakeholders to advance dog health and well-being. Let's take the momentum from this workshop and move forward with renewed energy and commitment to our shared goals.

     

    logo final square.jpg

    So Many to Thank…
    Thank you to our sponsors, Mars Petcare, Royal Canin, and Agria; our exhibitors, CombiBreed, Wisdom Panel, and Royal Canin; and all the poster presenters, discussion leaders, note takers, and the IPFD consulting team. And thank you to our Board of Directors for their leadership and commitment to ensuring IPFD’s signature events the IDHWs continue. Also, thank you to the Finnish Kennel Club and everyone who attended and contributed to the success of the International Dog Health Workshop 2024.

    I know that together, we’ll continue to affect positive change in the world of dogs. Watch for announcements on our plans for 2025 and 2026 this fall. Enjoy your summer!

     

    Warm regards,

    Marc Ralsky
    CEO, International Partnership for Dogs (IPFD)

  4. Brachycephalic obstructive airway syndrome (BOAS), observed in many flat-faced dog breeds, is one of the most urgent welfare problems in pedigree dogs.

    A Finnish study evaluated the results gained from the Finnish Kennel Club's (FKC) BOAS test and estimated the heritability for clinically graded BOAS signs. The BOAS test used by the FKC includes:

    • an exercise component with a recovery assessment,
    • BOAS grading by a veterinarian that evaluates upper respiratory signs before and after exercise, and
    • a nostril stenosis assessment.

    The analysed test results were from the years 2017–2022.

    BOAS grades.pngResults and conclusions:

    • The majority (80%) of dogs (n = 957) participating in FKC BOAS testing were English Bulldogs, French Bulldogs, and Pugs. In 2022, 89–100% of the litters from these three breeds registered with the FKC had at least one parent tested for BOAS.
    • The proportion of dogs failing the exercise test was highest in English Bulldogs (11%), followed by French Bulldogs (4%), and Pugs (3%).
    • In these three breeds, moderate to severe BOAS signs were reported in 28%, 22%, and 30% of dogs, respectively. The proportion of moderate to severe nostril stenosis was highest (71%) in Pugs, followed by French Bulldogs (55%), and English Bulldogs (40%).
    • Estimates of heritability for BOAS grade were separately calculated for these three breeds and for all dogs, and the estimates were moderate to high, ranging from 0.39 to 0.58.
    • The exercise test alone did not sufficiently identify dogs with moderate to severe BOAS signs.
    • To better consider the complex nature of BOAS and breed differences, exercise tolerance, the severity of upper respiratory signs (BOAS grade) and nostril stenosis should all be assessed together in breeding animals.
    • The heritability estimates for veterinary-assessed BOAS grade indicated that BOAS grade could be used in selective breeding to obtain less-affected offspring.

    The study is open access and can be read in the link below:

    Lilja-Maula, L.I.O., Mäki, K.H., Aromaa, M.K. et al. Evaluation of brachycephalic obstructive airway syndrome breeding test results in Finland from 2017 to 2022. Acta Vet Scand 66, 35 (2024). https://doi.org/10.1186/s13028-024-00755-9

  5. animal welfare - the human element.pngThis week is the anniversary of the First International Conference on Human Behaviour Change for Animal Welfare that took place in the UK 2016. All the talks are on their YouTube channel.

    See our article following the Conference.

    I was honoured to give a presentation - and in that process to learn about the knowledge, methodology, and tools available from human behaviour change theory and practice to help us.

    My talk is posted on the HBC's YouTube channel under the title:  How Beliefs and Attitudes about Dog Health and Welfare Limit Behaviour Change.

     

    In fact, the entire title was: 

    Don't Know or Don't Care? How Beliefs and Attitudes about Dog Health and Welfare Limit Behaviour Change.  

    See the Video Presentation and article/PDF presentation HERE

    and the video (below) is also available on YouTube...

     

    I am in general not a fan of watching videos of myself.  But this is a good talk - helped by the fact it was prescribed to be only 15 minutes long!

    However, reviewing this talk I was struck by something that was equally positive and extremely disappointing.

    The material in this talk is as relevant today as it was 4 years ago.  

    Perhaps even more so.  We are coming out with more material this week on challenges around brachycephalic dogs that will highlight the pros and cons of legislative actions, the diversity in opinions, even from those within the world of pedigree dogs, from total denial to intense concern.  There will be more talk about complexity, and the role of various stakeholders , e.g. veterinarians -- are they really doing all they can?

    I know that 4 years is not very long in terms of change for people or dogs.  But we have also recently completed a chapter for an upcoming textbook and that work highlighted that problems in flat-faced dogs have been discussed at least since the late 1960's.  So that is not 4 years, it is over 50 years.  There has been a phenomenal increase in evidence for the prevalence and high risk of health issues, many of which incur welfare concerns, in the worst affected breeds. This has intensified in the last 10 years as the popularity of these breeds has increased, and then skyrocketed (see our Get a GRIHP! article on French Bulldogs).  There have been many creative attempts to educate the public, and research to understand attachment to these dogs.

    Given all that.. I am sadly concerned that:

    • There may still be some 'Don't Know' people out there... and we can continue trying to reach them. 
    • But, unfortunately there are some people, some very loud on social media, some in positions of influence in the dog world, who are displaying behaviour that comes across as  'Don't Care'. 
    • At least it seems that they don't care ENOUGH about the dogs to be willing to undertake the human behaviour change needed to sustain a healthy future for the breeds they 'love'.

    We have to find a way to help people understand that admitting there are problems is the first step towards resolving them.

     

     

  6. Coefficient of Inbreeding vs. Genetic Diversity Level in Greyhoundsgreyhoundicon.PNG

    Coefficient of Inbreeding vs. Genetic Diversity Level in Greyhounds-update_2019.pdf

    IPFD Board member and veterinarian Barbara Thiel shared an English translation of this article which appeared in The Greyhound Show blog. The article includes a discussion of data available from the MyDogDNA on genetic diversity measurements in greyhounds - greyhound breeders are encouraged to read this document to gain perspective.

    Ideas presented on making assessments of genetic diversity are potentially useful considerations applicable to other breeds, i.e. ancestor loss and COI.

     

    Related material:

    See Brenda's blog:  Genetic Diversity: The Big Picture and Challenging Issues

     

     

     

  7. Working together: dog breeders, researchers, veterinarians, and kennel clubs have developed a truly international screening scheme for respiratory function. 

    UPDATE: 5/25/2023

    The OFA - just published info on participating in the Respiratory Function Grading Scheme  - see their Overview at https://ofa.org/diseases/rfgs/ - includes an event planning guide and instructions/rfgs forms.

     

    On 20 January 2023, I had the privilege of attending the Rose City Classic Dog Show, which included the North American launch of the Respiratory Function Grading Scheme (RFGS), colloquially known as the Cambridge BOAS scheme. The Orthopedic Foundation for Animals (OFA) is licensed by The Kennel Club in the UK, to administer the scheme and train new assessors. The scheme is currently offered formally to the British Bulldog, Pug, and French Bulldog, but other brachycephalic breeds are able to participate. Participation is quick, easy, and painless for the dog. 

    This scheme is many years in the making, and is an excellent example of collaboration between dog breeders, researchers, and kennel clubs working together to make steps towards addressing a complex and challenging health condition. Owners who participate in the scheme benefit from immediate information on key areas associated with risk of brachycephalic obstructive airway syndrome (BOAS) for their dog, as well as information for selecting breeding stock. They also directly contribute to a growing body of international data that supports genetic and veterinary researchers work to improve risk assessments.  

    Basic Steps of the Scheme:


    1.    Owners fill in a short survey

    2.    A brief physical examination of the dog, while calm, to establish a baseline

    3.    Dog has a brisk 3-minute walk (not running)

    4.    A post-walk assessment to compare to the baseline

    5.    Dogs are given a grade 0-3, with 0 being lowest risk and 3 being highest. Data is recorded, and in many cases available to view online. 

     

    image.jpeg

    Above: The dog is assessed in a quiet and relaxing space, with their owner. The specially trained assessors, all veterinarians, look at the nares (nostrils) and listen to the dog breathing. 

    image.jpeg

    Above: The screening session is recorded, along with data on the breathing. Standardized scoring cards are used to assess the nares. 

    Not pictured: Dogs undergo a timed 3-minute walk around a standard show ring. Dogs are not encouraged to run, but simply to walk at a reasonable, quick pace. 

    During my visit, I watched several dogs undergo the assessment. Speaking to the owners, the most common reasons they wanted to participate was to demonstrate that using the scheme was the right thing to do for the breed, to help grow awareness and use of the scheme, and as part of pre-breeding assessments. The assessors on the day had a steady stream of French Bulldogs, English Bulldogs, Pugs, and some Boston Terriers. While at the moment the screening scheme is designed for French Bulldogs, English Bulldogs, and Pugs, other brachycephalic breeds can utilize the scheme, gaining valuable information and contributing to research. I witnessed many owners who had dogs scoring Grades 0-1 (the lowest risks), both in young and older dogs. 

    It will take time to track how use of this scheme reduces the risk of BOAS in future generations of dogs, but at the very least the consistency in the data collection and the ability to identify higher-lower risk dogs to breeders is valuable and an important resource to brachycephalic breeds. 

     

    Accessing the RFGS screening scheme

    The scheme is available in the UK, and USA. The Federation Cynologique Internationale (FCI) also supports this screening scheme. Currently there are 11 countries currently offering the scheme: Australia, Denmark, Mexico, Netherlands, New Zealand, Portugal, Sweden, Switzerland. 8 more countries are in process for 2023. 

    More information on the scheme:

    UK: The Kennel Club and University of Cambridge's Respiratory Function Grading Scheme

    FCI Countries: Brachycephalic breeds' health: agreement between the Kennel Club (UK) and the FCI

    North America: 

    BOAS-RFGS-OVERVIEW-1.pdf

    The Kennel Club grading scheme details:

    FrenchbulldogandbulldoggradingschemeKC.pdf

     

     

    The views and opinions expressed by the authors and those providing information or comments on this website are theirs alone, and do not necessarily reflect the views, opinions or positions of the International Partnership for Dogs (IPFD) or DogWellNet.com.
    We make no representations as to accuracy, completeness, timeliness, suitability or validity of any information and will not be liable for any errors, omissions, or delays in this information or any losses, injuries or damages arising from its display or use.

  8. An outcome from the International Dog Health Workshop - Virtual, on Standardizing Genetic Testing, is to improve transparency on how genetic tests are performed - e.g. information on assays or other technical details. The primary focus of this was increasing transparency on where a linkage vs direct variant (mutation) test is being offered. 

     

    New HGTD Phenes resource:

    The phenes searchable database in HGTD has always provided genetic test provider (GTP)-specific information on how tests are undertaken, including the specific GTP-reported variants/mutations for each test they offer, especially where their test is different than the variants reported in the literature.

    The new option to include Assay/Test Information in the phenes database allows for comment not just specific to individual GTPs, and aims to add clarity where a test is exclusively linkage based, exclusively direct variant, or both. This should also improve transparency where we have reports of tests being performed as a linkage/markers tests by GTPs who are not participants in HGTD or who do not provide linkage/markers information to HGTD.

     

    Why would a linkage test be offered?

    A linkage or markers test may be the preferred test performance for a GTP for a number of reasons, including:

    • The direct variant(s) are difficult to assay or are part of a panel, and a linkage/markers assay is easier to perform consistently and robustly
    • The direct variant isn't known, and only a linkage/marker is available to test
    • The direct variant is patented or proprietary, and a linkage test is a way around this

     

    Why is it important to know if a test is a direct mutation or linkage test?

    While linkage tests are usually very accurate, generally, direct mutation tests are felt to be more robust so are often the preferred method of test performance by GTPs. Where a linkage test is used (for whatever reason), there may be an increased risk of false-results. This could explain why some owners have experienced different test results for the same genetic test, from different test providers. Knowing whether or not a test is performed as a direct mutation or as a linkage test can be helpful in increasing the confidence of a test result if there are concerns about accuracy. There can be many reasons a test result may appear to differ from the phenotype of a dog, however, so it is valuable to report to a genetic test provider when a test result is in question. It could be a testing error (including owner sampling errors), or that the phenotype is an unknown direct variant, variation on a known direct variant, or something else! In this way, we can work collaboratively to improve the robustness of genetic testing for everyone. It is worth noting that the majority of testing errors across all kinds of genetic tests are due to samples being incorrectly taken or submitted with the wrong dog details, which is why many GTPs offer to re-run a test where there are concerns about the result. 

     

    Additional Information:

    This week in HGTD: direct variant/mutation, linkage, and risk tests – what are they?

     

     

  9. National Kennel Clubs are major stakeholders in the governance and regulation of dog breeding. As such, they have been the targets of major criticism related to dog health issues. It is therefore interesting to investigate to what extent health and welfare is a priority for kennel clubs (KCs), and what are the capacities and actions implemented to deal with those issues.

     

    A survey was sent in 2017 to 40 KCs with 15 answers received from 11 European (Austria, Belgium, Denmark, France, Germany, Ireland, Latvia, The Netherlands, Norway, Sweden and the UK) and 4 non-European countries (Australia, Mexico, Uruguay, and the USA) aimed at describing and comparing information across countries in dog breed health management (Wang et al. 2018).

     

    First, in order to determine the population of dogs under the responsibility of KC, the percentages of all dogs being registered as ‘pedigree’ dogs were estimated considering the 15 surveyed KCs, as well 35 other countries, using sources such as the FCI online statistics. Across countries, the average and median percentage of the entire dog population that were registered pedigree dogs, respectively was 20% and 14%.  However, there was a large variation across countries, with European Nordic countries showing, in general, a larger proportion of pedigree dogs (see Figure 1). This aspect is of importance, since it is expected that the responsibility toward general dog health, as well as the capacity to improve the situation, relates to the proportion of dogs that are at least to some extent under the influence of the KCs.

    Fig1.jpg 

    When asked about the current challenges, KCs ranked exaggerated morphological features and inherited disorders as the most important issues, showing those two problems are now clearly identified as priorities (Figure 2). By contrast, issues such as economic constraints to breeding were rarely viewed as problematic for dog breeding. Kennel clubs also commented on challenges related to the difficulty to find balance between increased regulation and the risk of losing members; to achieve consensus and compliance of breeders and clubs toward breed health strategies; as well as lack of capacity regarding information provision and education.

     

    Fig2.jpg

    Surveyed countries showed great diversity in terms of information management, implementation of breeding strategies, recommendations, requirement, restriction and tools. Most KCs indicated that information on genealogies, breed standards and dog shows were recorded in their data base for most, if not all breeds; however, health information (e.g. screening examinations, genetic tests) was more sparsely recorded and provided to the public, both for breeds within countries and across countries (Figure 3). For instance, KCs from Austria, Australia, Denmark, France, Germany, The Netherlands, Norway, the UK and the USA provided health information status on pedigrees and in online data bases, but in general, not all breeds were covered. When considering implementation of breeding strategies, six countries indicated that there were no breeding strategies implemented by any breed clubs, while in three countries (Austria, Sweden and the Netherlands) it was reported that each breed club had its breeding strategy.

    Fig3.jpg

     

    Several countries indicated that they were planning to develop breeding tools and provide health information to users, and for instance, France and Belgium reported having ongoing work to develop tools to provide online pedigree with health information or estimate breeding values for complex disorders such as hip dysplasia.

     

    Although limited by the relatively low number of countries considered, this survey showed that despite large differences in their approach to breeding policies and management, the awareness to improve breeding and health of pedigree dogs was strong among the surveyed Kennel Clubs. The dog breeding world is increasingly global in scope.  The understanding of both the diversity of health initiatives and the potential for coordinated actions internationally is key to further efforts to promote dog health and welfare.

     

    There is probably still a lot of progress to be made in term of information provision and collection, as well as planning breeding strategies considering dog health. In particular, finding a consensus in terms of constraints and priorities for breeding, is expected to be particularly challenging for Kennel Clubs and breed clubs in order to implement those strategies. Although the situations differ across countries, exchanges of experiences may surely help to find the most adequate solutions toward improvement of health and welfare.

     

      

    Reference:

    Wang, S., Laloë, D., Missant, F. M., Malm, S., Lewis, T., Verrier, E., ... & Leroy, G. (2018). Breeding policies and management of pedigree dogs in 15 national kennel clubs. The Veterinary Journal. https://doi.org/10.1016/j.tvjl.2018.02.018

     

     

  10. Hello all!

     

    Brenda’s blog gave a great overview of the American Kennel Club National Parent Club Canine Health Conference we attended earlier this month in St. Louis, Missouri. I am grateful for the sponsorship from the Orthopedic Foundation for Animals provided to myself and the 31 other veterinary students in attendance.

     

    This conference, like the 3rd International Dog FullSizeRender 7.jpgHealth Workshop, was an opportunity to learn more about cutting edge research that is improving dog OFA Logo 2017.jpghealth. Topics were varied and included tick borne disease, epilepsy, lymphoma, and reproductive health. It was exciting to see my Colorado State University (CSU) Immunology professor, Dr. Anne Avery, present on her lymphoma research. 

     

     

     

    Right: View from the top of the St. Louis Gateway Arch

     

     

    Veterinary Student Attendees at the AKC National Parent Club ConferenceAfter completing a CSU clinical orthopedics rotation a few weeks prior to the conference, it was especially interesting to hear what I had learned about Omega-3 fatty acids in my rotation be reiterated by presenter Dr. Wendy Baltzer from Massey University. Her Purina funded study described that a diet high in Omega-3 fatty acids post-surgical correction of cranial cruciate ligament disease is helpful and results in less progression of arthritis and lameness.  

    I’m am looking forward to graduation in 9 months and continued  involvement in dog health. The opportunities I have received since first starting my IPFD project have been endless and I am very thankful for the DogWellNet.com community!

     

    Left: Veterinary Student Attendees at the AKC National Parent Club Health Conference

     
     
  11. Well, it's been 10 weeks... and I've learned quite a lot. I hope you have, too! As my project comes to an end, Nina and I wanted to give our viewers a big thank you. I hope you enjoyed this blog series and feel more confident about what your role is in solving antimicrobial resistance (AMR). We would also like to extend a huge thank you to the Skippy Frank Fund who sponsored this entire project, and a thank you to Dr. Jason Stull and Dr. Brenda Bonnett for being wonderful mentors every step of the way.

     

    It is important to keep in mind that science is an ever-changing field that is constantly updated with new material. For example there's a new study that just came out suggesting that not finishing a course of antibiotics may not cause resistance, which is contrary to the current belief. Here is the link to this article if you would like to read more about it. Even though this blog is over, I hope that you continue your AMR education as new scientific data arises. 

     

    To complete my summer project, I have constructed a poster that I will be presenting at The Ohio State University College of Veterinary Medicine's Research Day.

    Take a look!

     

    Slide1.thumb.PNG.2c6575c76e1d828f2cfd208703927bf8.PNG

     

     

    Here is the downloadable PDF version:

    IPFD Poster.pdf

     

     

     

     

    Be sure to keep checking www.DogWellNet.com for more information on dog health and wellness!

     

     

     

  12. blog-0240470001433429240.png

    Once a year, in October, the SKK Breeding Committee organizes a weekend course for

    breeding officials based on the book Dog breeding in theory and practice by Sofia Malm (SKK genetic expert) and Åsa Lindholm.

    blogentry-58-0-98774400-1433429215.png

     

     

     

     

     

    The Genetic Expert and The Breeding Consultant of the SKK Department for Breeding and Health are in charge of the course.

     

     

     

    The aim is to give breed clubs education and tools they need to work with breeding plans and breed-specific strategies.

     

     

     

    The contents of the course include basic genetics and guidance in how to conduct work at club level.

     

     

     

    There’s also a certain amount of self-directed studies.

     

     

     

     

    blogentry-58-0-62127900-1433429227.png

     

    Every other year, in April, this education is held specifically directed to hunting dog breed clubs.

     

     

  13. blogentry-68-0-75520200-1425905164_thumb

     

    On the podium:

    1st : Meisterhaus Signet Higher'N Higer ; Breed: Basenji ; Owner: Lise DURLOT and Dimitri HEBERT ; Breeder: Brenda CASSELL and Tad BOOKS

    2nd : Fall In Love Forest Ohara Of Bloom White ; Breed : Samoyede ; Owner: Mira MITKOVA ; Breeder: Elisabeth FAUCON

    3rd : Eternal Drago Of Nordic Forest ; Breed : Siberian Husky ; Owner and breeder: Valérie CHARNEAU

  • Blogs Disclaimer
    The contents of these blogs are for informational purposes only and represent the opinion of the author(s), and not that of the International Partnership for Dogs (IPFD). This is not intended to be a substitute for professional, expert or veterinarian advice, diagnosis, or treatment. We do not recommend or endorse any specific tests, providers, products, procedures, opinions, or other information that may be mentioned on, or linked to from these blogs.

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