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Get a GRIHP! on German Shepherds


    This article on German Shepherds is part of a series to highlight the Big Picture of health, welfare and breeding and to help develop Globally Relevant Integrated Health Profiles (GRIHPs) for many breeds.  See IPFD's Get a GRIHP! on Breed Health Initiative

    This is a 'living document' - so if anyone has more material to share or point us to - please let us know!

     

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    Photo: Freepik

     


     

    The German Shepherd at a Glance

    The German Shepherd is the most known and popular breed in the world. The breed has been bred with the ultimate objective of creating a working dog inclined to high achievements. 

    The German Shepherd Dog must be well-balanced (with strong nerves) in terms of character, self-assured, absolutely natural and (except for a stimulated situation) good-natured as well as attentive and willing to please. He must possess instinctive behavior, resilience and self-assurance in order to be suitable as a companion, guard, protection, service and herding dog. (source: FCI breed standard)

    German Shepherds are widely used in police, military, and search and rescue work. They are also kept as family pets and used in competitive protection and other hobbies. 

    The breed is divided into two genetically different lines: a working line focusing on competition and working dogs, and a show line focusing on appearance and dog shows. The division of the lines started in the former West Germany in the 1960s, and since the 1980s, there has been little mixing of the lines in Germany. In other countries, mixed-line dogs also exist, having both show and working dogs in the pedigrees. 

    The German Shepherd comes with two coat variants: the short-haired and the long-haired. The long-haired variant was approved in 2009 and is therefore still new to the breed, although long hair has existed within the breed throughout the ages.

     

    What Do Caretakers Need to Know?

    As very strong and active dogs, German Shepherds need good training and handling.


     


     

    Key Hereditary Health Conditions

    The major hereditary problems in the German Shepherd are immunological diseases and various skeletal diseases. The most common immunological diseases are atopy and allergies, pancreatic insufficiency, various tumours, pannus (pannus keratitis), and perianal fistula. The most common skeletal diseases are hip and elbow dysplasia. Also worth mentioning are spinal problems, growth disorders of the stifle and shoulder, gastric torsion, and heart disease. (Source: breeding strategy of the Finnish breed club)

    Disorder prevalence in UK German Shepherd Dogs by VetCompass Interactive Resources:

    1. Hip and elbow dysplasia
    2. Immunological eye diseases; plasmoma and keratitis
    3. Spinal and skeletal issues; lumbosacral transitional vertebrae, spondylosis and narrowing of the posterior spinal canal 
    4. Orthopedic; osteochondrosis in shoulders
    5. Degenerative myelopathy (DNA test available)
    6. Allergies and atopies
    7. Exocrine Pancreatic Insufficiency (EPI)
    8. Perianal fistulas (anal furunculosis)


     


           

    Physical Exaggerations – Instructions for Conformation Judges

    Breed-Specific Instructions of the Nordic Kennel Union

    FCI GROUP 1 – Sheepdogs and Cattledogs

    Areas of risk are:

    1. Hindquarters: Over-angulated and cow hocked hindquarters with instability in hocks.
    2. Top line: Arched and cut away in loin and croup.

    Exaggeration in presentation with extreme handling precludes assessment of the demands of the standard: “the position of hind legs is slightly backwards whereby the hind limbs are parallel to each other when seen from the rear”. Evaluation of the movement should be made at both trot and walk.

    Read more here >>

     

    Breed Watch UK

    Points of concern for special attention by judges:

    1. Cow hocks
    2. Excessive turn of stifle
    3. Nervous temperament
    4. Sickle hock
    5. Weak hindquarters

    Read more here >>

     

     


           

    Statistics (Morbidity and Mortality)

    Agria - Swedish Breed Profiles077ded1497d94bb45f713b7d0589f09f58d77800.webp

    We recommend that you download the Agria Breed Profiles for the German Shepherd and study them for full available information. Some excerpts are shown below.

    Download Profiles for 2006 – 2011 | Download Profiles for 2011 – 2016 | Download Profiles for 2016 – 2021

    (Access is free, but sign-in to DogWellNet is required).

    The great benefits of the Swedish Insurance Data are that they include almost 40% of the national population of dogs, and so are very representative. Note that animals at very old ages are likely under-represented. Most importantly, information is available on all insured dogs, not simply those who get sick or die.

    Extracts from Veterinary Care Events  MORBIDITY

    Relative risk of morbidity in German Shepherds compared to all breeds (Chart 1): 1.2 (The risk in the breed is larger than for All Breeds)

    Most frequent general causes (Chart 3): locomotor, digestive, skin, injury, neoplasia

    Most frequent specific causes (Chart 5): vomiting/diarrea/gastroenteritis, pain/symptom locomotor, dermatitis/pyoderma/folliculitis, otitis, itching, skin trauma, teeth, skin tumour, allergy/atopy

    Largest relative risks (specific causes) compared to All Breeds (Chart 6 – not included here):

    • exocrine pancreatic insufficiency >11 x,
    • panosteitis >9 x,
    • intestinal accident spleen >4 x, and
    • upper urinary tumour >4 x the risk in All Breeds.

    Locomotor compared to All Breeds (Chart 10): 

    • skeletal 4 x,
    • elbow 3 x,
    • hip/femur/pelvis 2,5 x, and
    • carpal/metacarpal >2 x the risk in All Breeds.

     

    More Info

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    UK VetCompass: Most frequent disorders

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    Extracts from Agria Breed Profile (Life)  MORTALITY

    Median Age (years) at death: 6.7, which is a little lower than in All Breeds (6.9).

    Relative Risk Mortality compared to All Breeds (Chart 1): 1.93. (The risk in the breed is almost twice the risk in All Breeds).

    Most frequent general causes of death (Chart 3): locomotor, neoplasia, digestive, dead/euthanized, neurological, skin. All are more common than in All Breeds.

    Most frequent specific causes of death (Chart 5): dead/euthanized, disc/vertebral, hip dysplasia, intest accident, ataxia/paresis/paralysis/collapse, locomotor pain/symptom, neoplasia. All are more common than in All Breeds.

    More Info

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    UK - VetCompass: Causes of death
     

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    Source: VetCompass Interactive Resources - Disorder prevalence in UK German Shepherd Dogs

     

    Finland – Finnish Kennel Club Mortality Data 2014->

    The average life expectancy according to the Finnish statistics is 8 years 2 months.

    The most common specified causes of death are

    • old age (at 11 years 10 months),
    • tumor/cancer (9 y 2 mo),
    • skeletal or articular disease (5 y and 8 mo), and
    • spinal disease (7 y 10 mo).


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    Source: Finnish Kennel Club breeding database

     

    Life Expectancy

     

     


     

    Health Screening

    DNA Tests – Harmonization of Genetic Testing for Dogs

    HGTD-logo-10-27-2020-web-png.pngThe Harmonization of Genetic Testing for Dogs (HGTD) is a large collaboration project run by the IPFD. The HGTD includes 82 academic and commercial genetic test providers (GTPs) in 26 countries.

    Our searchable database currently holds information on 300+ conditions/traits across all breeds/types.

    Breed Relevance Rating (BRR) indicates the level of available evidence supporting the application of a specific genetic test for a specific breed/type:

     green paw 20.jpg    Some, moderate or strong evidence from available research. The test may be meaningful or recommended for this breed.

     yellow paw 20.jpg   Currently no evidence of relevance for the use of this test in this breed, or the test is not known in this breed. This rating should be expected to change as evidence becomes available. 

     orange paw 20.jpg   All current available evidence has been reviewed, but relevance is inconclusive, and/or the clinical form of the disease has never been seen in this breed.

     red paw 20.jpg   All current evidence indicates that the test is not meaningful or recommended in this breed.

    Click here for more information on the HGTD project

     

    See the HGTD – DNA tests for the German Shepherd Double-coat here, and Long coat here

    Summary: German Shepherds have long been a popular breed, in turn making them one of the breeds with a larger selection of available genetic tests. There are two different recognised varieties: Double-coated, and Long and harsh coat. In some countries these populations have effectively not interbred for a long enough time that there are differences in recommended genetic tests. However, it may be prudent in pre-breeding applications to review the results for genetic tests offered to both varieties. Testing for Multidrug Resistance 1 (MDR1) is recommended for all german shepherd dogs, regarless of if they are being considered for breeding, due to the potential welfare/veterinary importance implications. The lists below reflect some of the breed-specific genetic tests with available research, divided by breed/variety. Please refer to the full information on HGTD for all available genetic tests, including those that may be relevant but do not currently have breed-specific research, as well as non-breed specific tests, or trait tests such as coat colour. 

    German Shepherd, Double coated

    Multidrug Resistance 1 (MDR1) 

    2,8-Dihydroxyadenine Urinary Stones 
       
    Achromatopsia 2 
       
    Degenerative Myelopathy 
        
    Dwarfism, Pituitary 
       
    Factor VIII Deficiency 
       
    Hyperuricosuria and Hyperuricemia (HUU) 
       
    Ichthyosis, ASPRV1-related (specifically identified in the German Shepherd)
       
    Leukocyte Adhesion Deficiency III (LAD3) 
       
    Mucopolysaccharidosis Type VII 
       
    Renal Cystadenocarcinoma and Nodular Dermatofibrosis 
       
    Scott Syndrome 
       
    Von Willebrand Disease I 
       
    X-linked Ectodermal Dysplasia 
       
    Achromatopsia (cone degeneration, hemeralopia), GSPT  (might be important)
     

    German Shepherd, Long and Harsh coat

     Multidrug Resistance 1 (MDR1) 
       
    2,8-Dihydroxyadenine Urinary Stones 
       
    Dwarfism, Pituitary 
       
    Factor VIII Deficiency 
       
    Hyperuricosuria and Hyperuricemia (HUU) 
       
    Mucopolysaccharidosis Type VII 
       
    Renal Cystadenocarcinoma and Nodular Dermatofibrosis 
       
    Von Willebrand Disease I 
       
    X-linked Ectodermal Dysplasia 
       
    Leukocyte Adhesion Deficiency III (LAD3) 
     

    ♦ BIG PICTURE THINKING ♦ Please take into consideration - Most of the conditions with genetic tests are rare in the general population, but valuable for breeders to use to efficiently reduce risks while supporting good genetic diversity in the breed as a whole. Also be aware that there are many DNA tests that are available for ALL breeds, and that while the test itself is valid, the condition may not be a major health concern or included in health strategies for every breed. See the HGTD for a full list of DNA tests including "Trait" and "Parentage" tests.

    There are a number of tests available, particularly tests for traits such as coat color, or health issues that are applicable to all dogs and may be important to specific breeding lines or breeding goals. We welcome contributions from breed experts and researchers to help us keep our information up to date. Email us at info@ipdfogs.com

     

    Health Screening Summary – By Country

    (Source: Breeding Strategies, see below)

    R1-Mandatory for registration
    R2-Recommended
    R3-Recognized

    Note: Please let us know if there have been changes to the health screening requirements in your country, so we can update our data. 

    Condition/  Trait

    GE

    FI

    FR

    IT

    NL

    NO

    SWE

    UK

    US

    Correct dentition

    R2

    R2

    R2

     

    R2

     

     

     

     

    Hip dysplasia

    R1

    R1

    R2

    R2

    R2

    R1

    R2

    R2

    R1

    Elbow dysplasia

    R1

    R1

    R2

    R2

    R2

    R2

    R1

    R2

    R1

    Eye disease/keratitis & plasmoma

     

    R2

     

     

     

     

     

    R2

    R2

    Spine

     

    R1**

     

     

    R2

    R2

    R2

     

     

    Character/

    mental test

    R1*

    R1

    R2

    R2

    R2

     

    R2

     

    R1

    DNA profile

    R2

     

    R2

     

     

     

     

     

     

    Allergy, atopy

     

    R2

     

     

     

    R3

    R2

     

     

    Cardiac disease

     

     

     

     

     

     

     

     

    R2

    Thyroid test

     

     

     

     

     

     

     

     

    R2

    Mega-esophagus

     

     

     

     

     

    R3

     

     

    R3

    Exocrine pancreatic insufficiency

     

     

     

     

     

    R3

     

     

    R3

    Bloat

     

     

     

     

     

     

     

     

    R3

    Epilepsy

     

     

     

     

    R2

     

     

     

    R3

    Hemangio-sarcoma

     

     

     

     

     

     

     

     

    R3

    Degerative myelopathy

     

    R3

     

     

    R2

     

     

    R2

    R2

    Haemophilia

     

     

     

     

     

     

     

    R2***

     

    Max N of offspring

     

     

     

     

    R2

     

     

     

     

    Dwarfism

     

     

     

     

    R2

     

     

     

     

    *Evaluated in Talentsichtung, trials and Körung; **Screening for lumbosacral transitional vertebrae (LTV) is mandatory, for spondylosis recommended; ***Only for males

    Note: The table above provides some of the most common health screening information from clubs in the countries listed. See the individual club websites for the most recent and accurate information on health management in the Cavalier breed.

     

    Breeding Strategies and Health Screening Statistics

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    Photo: Freepik

    Germany

    Health information/requirements by the breed clubs:

    • Verein für Deutsche Schäferhunde (SV) e.V. – Zuchtordnung
    • The German Shepherd Association RSV2000 eV – Zuchtordnung

    ”The German Shepherd Association RSV2000 eV sees itself as the heir to the idea of its founder Max von Stephanitz: The German Shepherd Dog should be bred as a versatile working dog.” (Source: https://www.rsv2000.de/ueber-den-rsv2000/)

    Breeding plan:

    image.png

     

    UK

    Scandinavian countries

    Percent healthy of the examined dogs (2013-2023):

    • Hip dysplasia: Finland 65 %, Norway 67 %, Sweden 74 %.
    • Elbow dysplasia:  Finland 81 %, Norway 86 %, Sweden 83 %.
    • Eye diseases: Finland 78 %, Norway 58 %, Sweden 70 %. 

    Clinical findings listed in the Norwegian Kennel Club database (in Norwegian):

    image.png

     

    France

    La Centrale Canine health statistics 2011-2020 documentDuring 2011-2020 the proportion of screened German Shepherds free of hip dysplasia has been 70-74%. However, there has been an increase in moderate and severe dysplasia (D and E) and a decrease of mild dysplasia (C). Proportion of screened dogs has been 10 %.


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    11 % of the screened dogs had elbow arthrosis (grades 1-3 elbow dysplasia) during 2011-2020:

    image.png

     

    The Netherlands

    Breeding rules of the breed clubs:

     

    Italy

     

    US

    OFA Statistics - % healthy of the examined dogs since 2021:

    • Hip dysplasia: 79%
    • Elbow dysplasia: 81%
    • Eye diseases: 95%
    • Cardiac (Advanced): 92%
    • Thyroid: 90 %
    • Degenerative myelopathy: 69%

     


     

    Research

    Ongoing research:

    Royal Veterinary College: Understanding the genetics of Canine inflammatory bowel disease (IBD) in GSDs

    Published research:

    O’Neill, D.G., Coulson, N.R., Church, D.B. et al. Demography and disorders of German Shepherd Dogs under primary veterinary care in the UK. Canine Genet Epidemiol 4, 7 (2017). https://doi.org/10.1186/s40575-017-0046-4

    The most frequent disorders in GSDs were otitis externa, osteoarthritis, diarrhoea, overweight/obesity and aggression, whilst the most common causes of death were musculoskeletal disorders and inability to stand. Aggression was more prevalent in males than in females.

    Teng, K.Ty., Brodbelt, D.C., Pegram, C. et al. Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom. Sci Rep 12, 6415 (2022). https://doi.org/10.1038/s41598-022-10341-6

    Life tables varied widely between breeds. Life tables generated by the current study allow a deeper understanding of the varied life trajectory across many types of dogs and offer novel insights and applications to improve canine health and welfare. The current study helps promote further understanding of life expectancy, which will benefit pet owners and the veterinary profession, along with many other sectors. 

    Vilson Å, Bonnett B, Hansson-Hamlin H, Hedhammar Å. Disease patterns in 32,486 insured German shepherd dogs in Sweden: 1995-2006. Vet Rec. 2013 Aug 3;173(5):116. doi: 10.1136/vr.101577. https://pubmed.ncbi.nlm.nih.gov/23812178/

    For veterinary care events (morbidity) GSDs were most over-represented for immunological disease, with a relative risk (RR) of 2.7, compared with the risk in all other breeds combined. The most common disease category (morbidity) in GSDs was skin disorders with an incidence rate of 346.8 cases per 10,000 dog years at risk. The highest RR for cause of death in GSDs compared with all other breeds was for skin conditions (RR=7.8). Locomotor disorders were the most common cause of death in GSDs. The GSD is predisposed to immune-related disorders, such as allergies, circumanal fistulae and exocrine pancreatic atrophy, with significantly increased risk compared with all other breeds. 

    Vilson 2016. Immunity, Microbiota & Immune-related Disorders in German Shepherd dogs. Doctoral Thesis, Swedish University of Agricultural Sciences, Uppsala. https://pub.epsilon.slu.se/13768/1/vilson_a_161028.pdf

    In an epidemiological study based on insurance data we described a breed-specific pattern of diseases in German Shepherd dogs (GSD) and confirmed that this breed is predisposed to immune-related disorders. A prospective study was performed in order to further investigate immunological changes in the GSD using a large number of dogs, 30 bitches and their litters, from the same kennel under well controlled natural conditions.

    Bergevi 2022. Mapping of allergic dermatitis in the Swedish Armed Forces’ German Shepherd dogs – Analysis of early skin assessments from a breeding perspective (In Swedish, with an English abstract). Master’s Thesis, Swedish University of Agricultural Sciences, Uppsala. https://stud.epsilon.slu.se/17774/1/Bergevi_F_20220523.pdf

    The results indicate that genetic progress in decreasing allergic dermatitis is possible by including the early skin assessments at FM’s [The Swedish Armed Forces] selection, preferably as breeding values for skin status, which is important since breeding females are selected at the age of 15 months.
     

     


     

    References and Resources
     

    Breed Clubs

    Germany

    Both clubs have open studbook, ie. breed-typical dogs without pedigrees can get an appendix pedigree.


    Finland


    France


    Italy


    The Netherlands


    Norway


    Sweden


    US


    UK

     

     

    IPFD/DogWellNet Resources for the German Shepherd

     


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