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DNA Tests - How to Choose Which Ones to Use

    Cathryn Mellersh, PhD
    Animal Health Trust, Suffolk, UK


    Presentation given at the 7th Tufts' Canine & Feline Breeding & Genetics Conference (2015)


    The article can be accessed at:




    • A DNA test gives information about the DNA sequence of an individual dog at a position in the genome that is known to influence a particular inherited trait.

    • Most DNA tests are for a specific mutation that has been shown to cause an inherited disorder.

    • Sometimes the mutation causes a 'cosmetic' trait, such as coat colour.

    • Currently, most DNA tests are for mutations that cause 'Mendelian' or genetically simple inherited disorders.

    • Increasingly DNA tests will become available for 'genetic risk factors,' which increase an individual's risk of developing a disorder but are not the 'whole story.'




    Some good information for owners and breeders - considerations for using DNA tests to identify, manage or reduce heritable disease.



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