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Genetic mapping of principal components of canine pelvic morphology


    Authors: Mark J. Fealey1, Joy Li2, Rebel J. E. Todhunter1, Ursula Krotscheck1, Kei Hayashi1, Marina J. McConkey1, Adam R. Boyko2,3, Jessica J. Hayward2,3 and Rory J. Todhunter1,3*

     

     

     

    cgelogov2.pngFealey et al. Canine Genetics and Epidemiology

    (2017) 4:4

    DOI 10.1186/s40575-017-0043-7

     

     

    Plain English Summary

     

    "Concentrated breeding effort to produce various body structures and behaviors to suit human demand has inadvertently produced unwanted traits and diseases that accompany the external appearance and behavior of dogs. Purebred dogs, which are predisposed, or not, to HD share common features of their shape and size, respectively.


    Thirteen unique anatomical features of the pelvis were measured on radiographs of 392 dogs of 51 breeds and 95 mixed breed dogs. Combinations of these measurements together described the shape and size of the pelvis. Male dogs had significantly larger pelves than female dogs. Genetic markers pointed to insulin-like growth factor-1 as a major driver of pelvic size. A second genetic marker was associated with ilial length and ischial width on canine chromosome 16.

     

    Conclusion: Based on the current study, pelvic shape alone was not strongly associated with canine hip dysplasia."

     

Edited by Ann Milligan


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