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Von Willebrand Disease I

Breed: Drentsche partridge dog/ Drentsche Patrijshond

Generic Phene Data

Breeds

General

Disease Name
Von Willebrand Disease I
Mutation
c.7142C>T
Mutation 2
c.7437G>A
Test Type
Genetic Disease/Disorder
Details
Von Willebrand?s disease (vWD) is a blood disease caused by a deficiency of von Willebrand Factor (vWF), an adhesive glycoprotein in the blood required for normal blood clotting. A lack of vWF impairs platelet stickiness and clumping. Symptoms can include: spontaneous hemorrhage from mucosal surfaces, nosebleeds, blood in the faeces, bloody urine, bleeding gums, excessive vaginal bleeding, bruising, prolonged bleeding after surgery or trauma, blood loss anemia. The inheritance of the severe forms (Types II and III) is autosomal recessive. The milder form (Type I) may be autosomal recessive or incompletely dominant. This is the most common hereditary blood clotting disorder in dogs.
Details 2
Von Willebrand?s disease (vWD) is a blood disease caused by a deficiency of von Willebrand Factor (vWF), an adhesive glycoprotein in the blood required for normal blood clotting. A lack of vWF impairs platelet stickiness and clumping. Symptoms can include: spontaneous hemorrhage from mucosal surfaces, nosebleeds, blood in the faeces, bloody urine, bleeding gums, excessive vaginal bleeding, bruising, prolonged bleeding after surgery or trauma, blood loss anemia. The inheritance of the severe forms (Types II and III) is autosomal recessive. The milder form (Type I) may be autosomal recessive or incompletely dominant. This is the most common hereditary blood clotting disorder in dogs.
Published
Brewer, G.J., Venta, P.J., Schall, W., Yuzbasiyan-Gurkan, V., Li, J. : DNA tests for von Willebrand?s disease in Dobermans, Scotties, Shelties and Manchester terriers. Canine Practice 23:45, 1998.

Breed Specific Data

Agrotis S.r.l.

GTP Name
Agrotis S.r.l.
Gene Name
VWF
Mutation
c.7437G>A

Anicom

GTP
GTP Name
Anicom
Gene Name
VWF
Mutation
c.7437G>A

BioBank AS

GTP Name
BioBank AS
Gene Name
VWF
Mutation
c.7437G>A

CAG GmbH Center for Animal Genetics

GTP Name
Center for Animal Genetics
Gene Name
VWF
Mutation
c.7437G>A
GTP Breed
Drentsche partridge dog/ Drentsche Patrijshond

Certagen GmbH

GTP Name
Certagen GmbH
Gene Name
VWF
Mutation
c.7437G>A

CMSCH

GTP
GTP Name
CMSCH
Gene Name
VWF
Mutation
c.7437G>A

EVG Diagnostics

GTP Name
EVG Molecular Diagnostics
Gene Name
VWF
Mutation
c.7437G>A

Genomia s.r.o

GTP Name
Genomia s.r.o
Gene Name
VWF
Mutation
c.7437G>A
GTP Breed
Drentsche partridge dog/ Drentsche Patrijshond

Genoscoper Laboratories Oy

GTP Name
Genoscoper Laboratories Oy
Gene Name
VWF
Mutation
c.7437G>A
GTP Breed
Drentsche partridge dog/ Drentsche Patrijshond

GenSol Diagnostics

GTP Name
GenSol Diagnostics
Gene Name
VWF
Mutation
c.7437G>A

INNO

GTP
GTP Name
INNO
Gene Name
VWF
Mutation
c.7437G>A

Laboratorios Labocor S.L.

GTP Name
Laboratorios Labocor S.L.
Gene Name
VWF
Mutation
c.7437G>A

Laboklin Gmbh & Co. KG

GTP Name
Laboklin Gmbh & Co. KG
Gene Name
VWF
Mutation
c.7437G>A
GTP Breed
Drentsche partridge dog/ Drentsche Patrijshond

Paw Print Genetics

GTP Name
Paw Print Genetics
Gene Name
VWF
Mutation
c.7437G>A

PharmaDNA

GTP
GTP Name
PharmaDNA
Gene Name
VWF
Mutation
c.7437G>A

Progènes-ADN

GTP Name
Progenes ADN
Gene Name
VWF
Mutation
c.7437G>A

Veterinary Genetics Laboratory

GTP Name
Veterinary Genetics Laboratory
Gene Name
VWF
Mutation
c.7437G>A
Inheritance
AR
GTP Breed
Drentsche partridge dog/ Drentsche Patrijshond

VetGen LLC

GTP Name
VetGen LLC
Gene Name
VWF
Mutation
c.7437G>A

VHL Genetics

GTP Name
VHL Genetics
Gene Name
VWF
Mutation
c.7437G>A

Wisdom Health (formerly Mars Veterinary)

GTP Name
Wisdom Health (formerly Mars Veterinary)
Gene Name
VWF
Mutation
c.7437G>A
GTP Breed
Drentsche partridge dog/ Drentsche Patrijshond

Zoolyx

GTP
GTP Name
Zoolyx
Gene Name
VWF
Mutation
c.7437G>A
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