Donate

Did you find our content interesting or helpful? Help support the IPFD enhance health, well-being and welfare for dogs everywhere.

Jump to content
International Partnership for Dogs - Enhancing Dog Health, Well-Being, and Welfare - Join Us
Search In
  • More options...
Find results that contain...
Find results in...

Von Willebrand Disease I

Breed: Rottweiler

Generic Phene Data

Breeds
Relevance Rating: All current available evidence has been reviewed, but relevancy is inconclusive, AND/OR the clinical form of this disease has never been seen for these breeds

General

Disease Name
Von Willebrand Disease I
Mutation
c.7142C>T
Mutation 2
c.7437G>A
Test Type
Genetic Disease/Disorder
Details
Von Willebrand?s disease (vWD) is a blood disease caused by a deficiency of von Willebrand Factor (vWF), an adhesive glycoprotein in the blood required for normal blood clotting. A lack of vWF impairs platelet stickiness and clumping. Symptoms can include: spontaneous hemorrhage from mucosal surfaces, nosebleeds, blood in the faeces, bloody urine, bleeding gums, excessive vaginal bleeding, bruising, prolonged bleeding after surgery or trauma, blood loss anemia. The inheritance of the severe forms (Types II and III) is autosomal recessive. The milder form (Type I) may be autosomal recessive or incompletely dominant. This is the most common hereditary blood clotting disorder in dogs.
Details 2
Von Willebrand?s disease (vWD) is a blood disease caused by a deficiency of von Willebrand Factor (vWF), an adhesive glycoprotein in the blood required for normal blood clotting. A lack of vWF impairs platelet stickiness and clumping. Symptoms can include: spontaneous hemorrhage from mucosal surfaces, nosebleeds, blood in the faeces, bloody urine, bleeding gums, excessive vaginal bleeding, bruising, prolonged bleeding after surgery or trauma, blood loss anemia. The inheritance of the severe forms (Types II and III) is autosomal recessive. The milder form (Type I) may be autosomal recessive or incompletely dominant. This is the most common hereditary blood clotting disorder in dogs.
Published
Brewer, G.J., Venta, P.J., Schall, W., Yuzbasiyan-Gurkan, V., Li, J. : DNA tests for von Willebrand?s disease in Dobermans, Scotties, Shelties and Manchester terriers. Canine Practice 23:45, 1998.

Breed Specific Info

Researched Breeds
Doberman Pincher

Breed Specific Data

Agrotis S.r.l.

GTP Name
Agrotis S.r.l.
Breed
Gene Name
VWF
Mutation
c.7437G>A

Anicom

GTP
GTP Name
Anicom
Breed
GTP Disease Name
von Willebrand Factor I
Gene Name
VWF
Mutation
c.7437G>A

BioBank AS

GTP Name
BioBank AS
Breed
Gene Name
VWF
Mutation
c.7437G>A

Certagen GmbH

GTP Name
Certagen GmbH
Breed
Gene Name
VWF
Mutation
c.7437G>A

CMSCH

GTP
GTP Name
CMSCH
Breed
Gene Name
VWF
Mutation
c.7437G>A

EVG Diagnostics

GTP Name
EVG Molecular Diagnostics
Breed
Gene Name
VWF
Mutation
c.7437G>A
Nature of test
mutation test
GTP- or Breed-Specific Publications
Am J Vet Res. 2001 Mar;62(3):364-9.

Genomia s.r.o

GTP Name
Genomia s.r.o
Breed
GTP Disease Name
von Willebrand Factor I
Gene Name
VWF
Mutation
c.7437G>A
Nature of test
mutation test
FCI Number
147
GTP Breed
Rottweiler

GenSol Diagnostics

GTP Name
GenSol Diagnostics
Breed
GTP Disease Name
von Willebrand Factor I
Gene Name
VWF
Mutation
c.7437G>A

INNO

GTP
GTP Name
INNO
Breed
Gene Name
VWF
Mutation
c.7437G>A

Laboratorios Labocor S.L.

GTP Name
Laboratorios Labocor S.L.
Breed
Gene Name
VWF
Mutation
c.7437G>A

PharmaDNA

GTP
GTP Name
PharmaDNA
Breed
Gene Name
VWF
Mutation
c.7437G>A

Independent Veterinary Laboratory POISK

GTP Name
Independent Veterinary Laboratory POISK
Breed
GTP Disease Name
von Willebrand Factor I
Gene Name
VWF
Mutation
c.7437G>A

Progènes-ADN

GTP Name
Progenes ADN
Breed
Gene Name
VWF
Mutation
c.7437G>A

VHL Genetics

GTP Name
VHL Genetics
Breed
Gene Name
VWF
Mutation
c.7437G>A

Zoolyx

GTP
GTP Name
Zoolyx
Breed
Gene Name
VWF
Mutation
c.7437G>A
×
×
  • Create New...

Important Information

By using this site, you agree to our Terms of Use.