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Von Willebrand Disease I

Breed: Toy Manchester Terrier

Generic Phene Data

Breeds

General

Disease Name
Von Willebrand Disease I
Mutation
c.7142C>T
Mutation 2
c.7437G>A
Test Type
Genetic Disease/Disorder
Details
Von Willebrand?s disease (vWD) is a blood disease caused by a deficiency of von Willebrand Factor (vWF), an adhesive glycoprotein in the blood required for normal blood clotting. A lack of vWF impairs platelet stickiness and clumping. Symptoms can include: spontaneous hemorrhage from mucosal surfaces, nosebleeds, blood in the faeces, bloody urine, bleeding gums, excessive vaginal bleeding, bruising, prolonged bleeding after surgery or trauma, blood loss anemia. The inheritance of the severe forms (Types II and III) is autosomal recessive. The milder form (Type I) may be autosomal recessive or incompletely dominant. This is the most common hereditary blood clotting disorder in dogs.
Details 2
Von Willebrand?s disease (vWD) is a blood disease caused by a deficiency of von Willebrand Factor (vWF), an adhesive glycoprotein in the blood required for normal blood clotting. A lack of vWF impairs platelet stickiness and clumping. Symptoms can include: spontaneous hemorrhage from mucosal surfaces, nosebleeds, blood in the faeces, bloody urine, bleeding gums, excessive vaginal bleeding, bruising, prolonged bleeding after surgery or trauma, blood loss anemia. The inheritance of the severe forms (Types II and III) is autosomal recessive. The milder form (Type I) may be autosomal recessive or incompletely dominant. This is the most common hereditary blood clotting disorder in dogs.
Published
Brewer, G.J., Venta, P.J., Schall, W., Yuzbasiyan-Gurkan, V., Li, J. : DNA tests for von Willebrand?s disease in Dobermans, Scotties, Shelties and Manchester terriers. Canine Practice 23:45, 1998.

Breed Specific Data

Progènes-ADN

GTP Name
Progenes ADN
Gene Name
VWF
Mutation
c.7437G>A

CMSCH

GTP
GTP Name
CMSCH
Gene Name
VWF
Mutation
c.7437G>A

Laboratorios Labocor S.L.

GTP Name
Laboratorios Labocor S.L.
Gene Name
VWF
Mutation
c.7437G>A

Agrotis S.r.l.

GTP Name
Agrotis S.r.l.
Gene Name
VWF
Mutation
c.7437G>A

VHL Genetics

GTP Name
VHL Genetics
Gene Name
VWF
Mutation
c.7437G>A

Paw Print Genetics

GTP Name
Paw Print Genetics
GTP Disease Name
von Willebrand Factor I
Gene Name
VWF
Mutation
c.7437G>A
Nature of test
mutation test
FCI Number
-68

Anicom

GTP
GTP Name
Anicom
GTP Disease Name
von Willebrand Factor I
Gene Name
VWF
Mutation
c.7437G>A

Wisdom Health (formerly Mars Veterinary)

GTP Name
Wisdom Health (formerly Mars Veterinary)
GTP Disease Name
von Willebrand Factor I
Gene Name
VWF
Mutation
c.7437G>A
Nature of test
mutation test
FCI Number
-68
GTP Breed
Toy Manchester Terrier

Genoscoper Laboratories Oy

GTP Name
Genoscoper Laboratories Oy
GTP Disease Name
von Willebrand Factor I
Gene Name
VWF
Mutation
c.7437G>A
Nature of test
mutation test
FCI Number
-68
GTP Breed
Toy Manchester Terrier

PharmaDNA

GTP
GTP Name
PharmaDNA
Gene Name
VWF
Mutation
c.7437G>A

BioBank AS

GTP Name
BioBank AS
Gene Name
VWF
Mutation
c.7437G>A

Zoolyx

GTP
GTP Name
Zoolyx
Gene Name
VWF
Mutation
c.7437G>A

GenSol Diagnostics

GTP Name
GenSol Diagnostics
GTP Disease Name
von Willebrand Factor I
Gene Name
VWF
Mutation
c.7437G>A

Independent Veterinary Laboratory POISK

GTP Name
Independent Veterinary Laboratory POISK
GTP Disease Name
von Willebrand Factor I
Gene Name
VWF
Mutation
c.7437G>A

Certagen GmbH

GTP Name
Certagen GmbH
Gene Name
VWF
Mutation
c.7437G>A

INNO

GTP
GTP Name
INNO
Gene Name
VWF
Mutation
c.7437G>A
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