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Episodic Falling

Breed: American Hairless (Rat) Terrier

Breeds

Relevance Rating: Some evidence for test being meaningful in this breed

Relevance Rating: Unknown, not evaluated or no evidence for test for these breeds

General

Disease Name
Episodic Falling
Mutation
15.7kb microdeletion of exons 1, 2, and 3
Test Type
Genetic Disease/Disorder
Details
Episodic falling is a neurological condition, induced by exercise, excitement or frustration, in which muscle tone increases. This means the dog is unable to relax its muscles, becomes rigid and falls over. Affected dogs usually start to demonstrate clinical signs before one year of age, with most cases having their first episode aged four to seven months. (from AHT, 2018) Not to be confused with simmilar appearing epilepsy.
Details 2
Episodic falling is a neurological condition, induced by exercise, excitement or frustration, in which muscle tone increases. This means the dog is unable to relax its muscles, becomes rigid and falls over. Affected dogs usually start to demonstrate clinical signs before one year of age, with most cases having their first episode aged four to seven months. (from AHT, 2018) Not to be confused with simmilar appearing epilepsy.
Published
Gill,J.L.,Tsai,K.L.,Krey,C.,Noorai,R.E.,Vanbellinghen,J.F.,Garosi,L.S.,Shelton,G.D.,Clark,L.A.,Harvey,R.J.: AcanineBCANmicrodeletionassociatedwithepisodicfallingsyndrome.NeurobiolDis45:130-6,2012.Pubmedreference:21821125.DOI:10.1016/j.nbd.2011.07.014.
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