Generic Phene Data
GTPs
General
Disease Name
Coat Colour, Extension
OMIA
1199
Gene Name
MC1R
Mutation
c.916C>T
Mutation 2
p.R306*
Mutation 3
c.790A>G; g.233G>T
OMIM
266300
Test Type
Other Genetic Traits
Details
Testing for extension reveals whether a dog with a mask has one or two copies of this version of the extension locus. Dogs with a single copy can produce offspring with or without a mask, while those with two copies will only produce masked offspring.
Details 2
Testing for extension reveals whether a dog with a mask has one or two copies of this version of the extension locus. Dogs with a single copy can produce offspring with or without a mask, while those with two copies will only produce masked offspring.
Published
Newton, J.M., Wilkie, A.L., He, L., Jordan, S.A., Metallinos, D.L., Holmes, N.G., Jackson, I.J., Barsh, G.S. : Melanocortin 1 receptor variation in the domestic dog Mammalian Genome 11:24-30, 2000. Pubmed reference: 10602988.
Published 2
Everts, R.E., Rothuizen, J., van, Oost, B.A. : Identification of a premature stop codon in the melanocyte-stimulating hormone receptor gene (MC1R) in Labrador and Golden retrievers with yellow coat colour Animal Genetics 31:194-199, 2000. Pubmed reference: 10895310.
Published 3
Schmutz, S.M., Berryere, T.G., Goldfinch, A.D. : TYRP1 and MC1R genotypes and their effects on coat color in dogs Mammalian Genome 13:380-387, 2002. Pubmed reference: 12140685. DOI: 10.1007/s00335-001-2147-2.
Body/System/Process
Coat Colour/Pattern/Type
OMIA Url
Inheritance
A
Breed Specific Data
Genomia s.r.o
Link to GTP
GTP
Breed
GTP Disease Name
EM Locus
Gene Name
MC1R
Mutation
c.790A>G
Nature of test
mutation test
