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Coat Colour Dilution, Alopecia

Breed: Alaskan Husky

Breeds

Relevance Rating: There is some evidence or research available for these breeds

ALL
Kai
Pug

General

Disease Name
Coat Colour Dilution, Alopecia
Mutation
c.-22G>A
Mutation 2
c.705G>C
Test Type
Other Genetic Traits
Details
Responsible for "dilute" pigmentation, and colour dilution-related alopecia (CDA). CDA causes patches of hair thinning or loss, and may also include flaky and/or itchy skin. The condition is most commonly seen in dogs with a "blue" or "fawn" coat. As some tests are breed or type specific, please use care when selecting the right test for your dog
Published
Drögemüller, C., Philipp, U., Haase, B., Günzel-Apel, A.R., Leeb, T. : A noncoding melanophilin gene (MLPH) SNP at the splice donor of exon 1 represents a candidate causal mutation for coat color dilution in dogs. J Hered 98:468-73, 2007. Pubmed reference: 17519392. DOI: 10.1093/jhered/esm021.

Breed Specific Info

Researched Breeds
Chow Chow
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