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Factor XI Deficiency

Breed: Jack Russell Terrier

Generic Phene Data

Breeds

Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful for these breeds

General

Disease Name
Factor XI Deficiency
Mutation
ins90bpSine(polyA) in exon 7
Test Type
Genetic Disease/Disorder
Details
Blood coagulation problems noted in pregnant/ postpartum females. Some animals prolonged bleeding from injuries/surgeries.
Published
Tcherneva, E., Huff, A. M., Giger, U. : Coagulation factor XI deficiency in Kerry blue terrier dogs is caused by an exonic sine insertion Journal of Veterinary Internal Medicine 20:767 only, 2006.

Breed Specific Data

Agrotis S.r.l.

GTP Name
Agrotis S.r.l.
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.

BioBank AS

GTP Name
BioBank AS
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.

Certagen GmbH

GTP Name
Certagen GmbH
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.

CMSCH

GTP
GTP Name
CMSCH
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.

DNA My Dog

GTP Name
DNA My Dog
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Nature of test
mutation test
GTP- or Breed-Specific Publications
Tcherneva, E., Huff, A. M., Giger, U. : Coagulation factor XI deficiency in Kerry blue terrier dogs is caused by an exonic sine insertion Journal of Veterinary Internal Medicine 20:767 only, 2006.
Application in the Breed
Carriers can be bred to normal animals (N/fIX x N/N) .Offspring should be tested before breeding. No breeding of two carriers (N/fIX x N/fIX). Blood coagulation problems noted in pregnant/ postpartum females. Some animals prolonged bleeding from injuries/surgeries.
Inheritance
AR
This test is outsourced to:
Orivet
FCI Number
345
GTP Breed
Jack Russell Terrier

INNO

GTP
GTP Name
INNO
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.

Laboratorios Labocor S.L.

GTP Name
Laboratorios Labocor S.L.
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.

Orivet Genetic Pet Care

GTP Name
Orivet Genetic Pet Care
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Nature of test
mutation test
GTP- or Breed-Specific Publications
Tcherneva, E., Huff, A. M., Giger, U. : Coagulation factor XI deficiency in Kerry blue terrier dogs is caused by an exonic sine insertion Journal of Veterinary Internal Medicine 20:767 only, 2006.
Application in the Breed
Carriers can be bred to normal animals (N/fIX x N/N) .Offspring should be tested before breeding. No breeding of two carriers (N/fIX x N/fIX). Blood coagulation problems noted in pregnant/ postpartum females. Some animals prolonged bleeding from injuries/surgeries.
Inheritance
AR
FCI Number
345
GTP Breed
Jack Russell Terrier

PharmaDNA

GTP
GTP Name
PharmaDNA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.

Progènes-ADN

GTP Name
Progenes ADN
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.

VHL Genetics

GTP Name
VHL Genetics
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.

Zoolyx

GTP
GTP Name
Zoolyx
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
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