Reminder: Login to access new features and members-only content!

Register to be a member of our community. Its easy!

Register a new account

Already a member?

Log In here!

Donate

Did you find our content interesting or helpful? Help support the IPFD enhance health, well-being and welfare for dogs everywhere.

Jump to content
  •   Language
  • Sign Up

International Partnership for Dogs - Enhancing Dog Health, Well-Being, and Welfare - Join Us.

Factor VIII Deficiency

Breed: Havanese

Generic Phene Data

Breeds

Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful in this breed

General

Disease Name
Factor VIII Deficiency
Mutation
c.1412C>G
Mutation 2
c.1643G>A
Test Type
Genetic Disease/Disorder
Details
Factor XIII deficiency causes an impaired coagulability of the blood, with a consequential strong tendency to bleed, due to a deficiency of clotting factor VIII. Since the gene for this factor is located on the X chromosome, the disorder is expected to be X-linked.
Details 2
Factor XIII deficiency causes an impaired coagulability of the blood, with a consequential strong tendency to bleed, due to a deficiency of clotting factor VIII. Since the gene for this factor is located on the X chromosome, the disorder is expected to be X-linked.
Published
Hough, C., Kamisue, S., Cameron, C., Notley, C., Tinlin, S., Giles, A., Lillicrap, D. : Aberrant splicing and premature termination of transcription of the FVIII gene as a cause of severe canine hemophilia A: Similarities with the intron 22 inversion mutation in human hemophilia Thrombosis & Haemostasis 87:659-665, 2002. Pubmed reference: 12008949.

Breed Specific Data

Agrotis S.r.l.

GTP Name
Agrotis S.r.l.
Breed
Gene Name
FVIII
Mutation
c.1412C>G; c.1643G>A; c.1643G>A

BioBank AS

GTP Name
BioBank AS
Breed
Gene Name
FVIII
Mutation
c.1412C>G; c.1643G>A; c.1643G>A

Certagen GmbH

GTP Name
Certagen GmbH
Breed
Gene Name
FVIII
Mutation
c.1412C>G; c.1643G>A; c.1643G>A

CMSCH

GTP
GTP Name
CMSCH
Breed
Gene Name
FVIII
Mutation
c.1412C>G; c.1643G>A; c.1643G>A

INNO

GTP
GTP Name
INNO
Breed
Gene Name
FVIII
Mutation
c.1412C>G; c.1643G>A; c.1643G>A

Laboratorios Labocor S.L.

GTP Name
Laboratorios Labocor S.L.
Breed
Gene Name
FVIII
Mutation
c.1412C>G; c.1643G>A; c.1643G>A

Laboklin Gmbh & Co. KG

GTP Name
Laboklin Gmbh & Co. KG
Breed
GTP Disease Name
Factor VIII Deficiency or Hemophilia A; mutation originally found in Old English Sheepdog
Gene Name
FVIII
Mutation
c.1412C>G
Nature of test
mutation test
FCI Number
250

PharmaDNA

GTP
GTP Name
PharmaDNA
Breed
Gene Name
FVIII
Mutation
c.1412C>G; c.1643G>A; c.1643G>A

Progènes-ADN

GTP Name
Progenes ADN
Breed
Gene Name
FVIII
Mutation
c.1412C>G; c.1643G>A; c.1643G>A

Veterinary Genetics Laboratory

GTP Name
Veterinary Genetics Laboratory
Breed
GTP Disease Name
Factor VIII Deficiency or Hemophilia A; mutation originally found in Old English Sheepdog
Gene Name
FVIII
Mutation
c.1412C>G
Nature of test
mutation test

VetGen LLC

GTP Name
VetGen LLC
Breed
Gene Name
unpublished
Mutation
c.1412C>G

VHL Genetics

GTP Name
VHL Genetics
Breed
Gene Name
FVIII
Mutation
c.1412C>G; c.1643G>A; c.1643G>A

Wisdom Health (formerly Mars Veterinary)

GTP Name
Wisdom Health (formerly Mars Veterinary)
Breed
GTP Disease Name
Factor VIII Deficiency or Hemophilia A; mutation originally found in Old English Sheepdog
Gene Name
FVIII
Mutation
c.1643G>A; p.Cys548Tyr
Nature of test
mutation test
FCI Number
250
GTP Breed
Havanese

Zoolyx

GTP
GTP Name
Zoolyx
Breed
Gene Name
FVIII
Mutation
c.1412C>G; c.1643G>A; c.1643G>A
×
×
  • Create New...

Important Information

By using this site, you agree to our Terms of Use.