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Hair, Long

Breed: Yorkshire Terrier

Generic Phene Data

General

Disease Name
Hair, Long
Disease Name 2
Hair Length
OMIA
439
Gene Name
FGF5
Mutation
c.284G>T
Mutation 2
c.556_571del16
Mutation 3
c.559_560dupGG
Mutation 4
c.578C>T
Test Type
Other Genetic Traits
Details
Testing for a long coat can be useful for predicting possible breeding outcomes, which may be particularly useful for those concerned with coat length for meeting typical breed attributes.
Details 2
The long coat is caused by a recessive genetic mutation in the FGF5 gene.
Published
Housley, DJ., Venta, PJ. : The long and the short of it: evidence that FGF5 is a major determinant of canine 'hair'-itability. Anim Genet 37:309-15, 2006. Pubmed reference: 16879338. DOI: 10.1111/j.1365-2052.2006.01448.x.
Published 2
Cadieu, E., Neff, M.W., Quignon, P., Walsh, K., Chase, K., Parker, H.G., Vonholdt, B.M., Rhue, A., Boyko, A., Byers, A., Wong, A., Mosher, D.S., Elkahloun, A.G., Spady, T.C., André, C., Lark, K.G., Cargill, M., Bustamante, C.D., Wayne, R.K., Ostrander, E.A. : Coat variation in the domestic dog is governed by variants in three genes. Science 326:150-3, 2009. Pubmed reference: 19713490. DOI: 10.1126/science.1177808.
Published 3
Dierks, C., Mömke, S., Philipp, U., Distl, O. : Allelic heterogeneity of FGF5 mutations causes the long-hair phenotype in dogs. Anim Genet 44:425-31, 2013. Pubmed reference: 23384345. DOI: 10.1111/age.12010.
Published 4
Parker, H.G., Harris, A., Dreger, D.L., Davis, B.W., Ostrander, E.A. : The bald and the beautiful: hairlessness in domestic dog breeds. Philos Trans R Soc Lond B Biol Sci 372:, 2017. Pubmed reference: 27994129. DOI: 10.1098/rstb.2015.0488.
Body/System/Process
Coat Colour/Pattern/Type
Inheritance
AR

Breed Specific Data

Genomia s.r.o

Link to GTP
OMIA
GTP Disease Name
L Locus (Long Hair/Fluffy)
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16; c.559_560dupGG; c.578C>T
Nature of test
mutation test
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