DonateGastrointestinal Stromal Tumor
General
Disease Name
Gastrointestinal Stromal Tumor
Mutation
g.50110841_50110846delGGAAGG
Mutation 2
g.50110838_50110843delAGTGGA
Details
Primary gastrointestinal (GI) mesenchymal neoplasms in the dog include histologically similar entities such as leiomyomas, leiomyosarcomas, and gastrointestinal stromal tumors (GISTs)...Canine GISTs usually occur in older dogs, most commonly in the small intestine and colon...The clinical behavior of canine GISTs ranges from benign to malignant with metastases to the liver, spleen, mesentery, or mesenteric lymph nodes. (Gillespie et al, 2011)
Details 2
Primary gastrointestinal (GI) mesenchymal neoplasms in the dog include histologically similar entities such as leiomyomas, leiomyosarcomas, and gastrointestinal stromal tumors (GISTs)...Canine GISTs usually occur in older dogs, most commonly in the small intestine and colon...The clinical behavior of canine GISTs ranges from benign to malignant with metastases to the liver, spleen, mesentery, or mesenteric lymph nodes. (Gillespie et al, 2011)
Published
Gregory-Bryson, E., Bartlett, E., Kiupel, M., Hayes, S., Yuzbasiyan-Gurkan, V. : Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11. BMC Cancer 10:559, 2010. Pubmed reference: 20950418. DOI: 10.1186/1471-2407-10-559.
