Lundehund syndrome (LS) also known as the Lundehund intestinal syndrome is a gastrointestinal disorder.The Lundehund syndrome comprises several disorders together: protein-losing enteropathy (PLE), intestinal lymphangiectasia, gastrointestinal disturbance, inflammatory bowel disease and malabsorption. Other signs include: Clinical signs include diarrhea, vomiting, loss of appetite, weight loss, edema, swollen abdomen and/or swollen legs, low serum protein, especially albumin and apathy. Low levels of albumin are sometimes the only sign of the disorder. Hypoalbuminemia is sometimes accompanied with hyperglobulinaemia, reduced levels of fructosamines and vitamin B, hypo- or hypercalcemia, as well as high levels of serum folate and alanine aminotransferase. The condition can eventually lead to lymphoma or cancer of the intestines or stomach. Age of onset 2-11 years of age. . Metzger et al. (2016) stated "the Lundehund harbors a breed disposition for a syndrome comprising particular features of protein-losing enteropathy (PLE), intestinal lymphangiectasia, gastrointestinal disturbance, inflammatory bowel disease and malabsorption designated as Lundehund syndrome (LS) . . . . Clinical signs are diarrhea, vomiting, weight loss, edema and apathy often accompanied with decreased concentrations of albumin and globulin in blood profile"