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Coat Colour Panda White Spotting


Relevance Rating: There is some evidence or research available in this breed


Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful for these breeds


Disease Name
Coat Colour Panda White Spotting
Mutation 2
Test Type
Other Genetic Traits
The Panda coat pattern is characterized by symmetrical markings of white forelock, chest, abdomen, collar, muzzle, and tip of the tail. The amount of white can vary. In the homozygous state (2 copies of the mutation), the Panda mutation is considered embryonic lethal as no live dogs with the pattern and with 2 copies of the mutation have been observed. Heterozygous (1 copy of the mutation) dogs do not have any reported health defects associated with this coat pattern.
Details 2
Variable degree of white spotting ranging from tiny white spots up to completely white animals. The absence of pigment is caused by the absence of skin melanocytes. The white-spotting allele appears to be autosomal dominant with respect to coat colour and recessive lethal.
Wong, A.K., Ruhe, A.L., Robertson, K.R., Loew, E.R., Williams, D.C., Neff, M.W. : A de novo mutation in KIT causes white spotting in a subpopulation of German Shepherd dogs. Anim Genet 44:305-10, 2013. Pubmed reference: 23134432. DOI: 10.1111/age.12006.
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