Jump to content
International Collaboration For Dog Health And Welfare. Join Us.

Primary Open Angle Glaucoma (POAG) ADAMTS10

General

Disease Name
Primary Open Angle Glaucoma (POAG) ADAMTS10
OMIA
1870
Gene Name
ADAMTS10
Mutation
g.53101896G>A
Mutation 2
p.G661R
Mutation 3
c.1981G>A
Mutation 4
c.del2986_2991
Mutation Notes
mutations are breed-specific
OMIM
137760
Disease Code
POAG
Test Type
Genetic Disease/Disorder
Details
Primary open angle glaucoma, also known as POAG, is a painful condition where the pressure in the eye(s) increases over time eventually leading to blindness.
Details 2
Primary open angle glaucoma, also known as POAG, is a painful condition where the pressure in the eye(s) increases over time eventually leading to blindness.
Published
Kuchtey, J., Olson, L.M., Rinkoski, T., Mackay, E.O., Iverson, T.M., Gelatt, K.N., Haines, J.L., Kuchtey, R.W. : Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma. PLoS Genet 7:e1001306, 2011. Pubmed reference: 21379321. DOI: 10.1371/journal.pgen.1001306.
Published 2
Ahonen, Saija & Kaukonen, Maria & Nussdorfer, Forrest & D Harman, Christine & Komaromy, Andras & Lohi, Hannes. (2014). A Novel Missense Mutation in ADAMTS10 in Norwegian Elkhound Primary Glaucoma. PloS one. 9. e111941. 10.1371/journal.pone.0111941.
Body/System/Process
Eye
Inheritance
AR
Gene Name Text
ADAM metallopeptidase with thrombospondin type 1 motif, 10
×
×
  • Create New...

Important Information

By using this site, you agree to our Terms of Use.