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Progressive Retinal Atrophy


Relevance Rating: Unknown, not evaluated or no evidence for test in this breed


Disease Name
Progressive Retinal Atrophy
Test Type
Genetic Disease/Disorder
Retina cells are lost slowly, with intial signs of problems seeing in dim light. May progress slowly to complete blindness.
Details 2
This particular form of PRA was first mentioned by Goldstein et al. (2006), whoconcluded clinical signs are very similar to Progressive rod-cone degeneration (prcd) (OMIA 001298-9615) in a wide range of breeds, the Basenji disorder is not allelic to prcd.
Goldstein, O., Zangerl, B., Pearce-Kelling, S., Sidjanin, D.J., Kijas, J.W., Felix, J., Acland, G.M., Aguirre, G.D. : Linkage disequilibrium mapping in domestic dog breeds narrows the progressive rod-cone degeneration interval and identifies ancestral disease-transmitting chromosome. Genomics 88:541-50, 2006. Pubmed reference: 16859891. DOI: 10.1016/j.ygeno.2006.05.013
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