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Coat Colour, Grizzle
Breeds
Relevance Rating: There is some evidence or research available for these breeds
General
Disease Name
Coat Colour, Grizzle
OMIA
1495
Gene Name
MC1R
Mutation
c.233G>T
Mutation 2
p.G78V
Test Type
Other Genetic Traits
Details
Grizzle (also called domino) is a pattern of dark pigment (eumelanin) on the top surface of the head, body and tops of the legs; light pigment (pheomelanin) is present on the lower legs, undersides and up the face around the eyes. The distinctive face pattern is often referred to as a widow?s peak. A typical example can be found in the markings on Afghan Hounds.
Details 2
Grizzle (also called domino) is a pattern of dark pigment (eumelanin) on the top surface of the head, body and tops of the legs; light pigment (pheomelanin) is present on the lower legs, undersides and up the face around the eyes. The distinctive face pattern is often referred to as a widow?s peak. A typical example can be found in the markings on Afghan Hounds.
Published
Dreger, DL., Schmutz, SM. : A new mutation in MC1R explains a coat color phenotype in 2 "Old" breeds: Saluki and Afghan Hound. J Hered :, 2010. Pubmed reference: 20525767. DOI: 10.1093/jhered/esq061.
Body/System/Process
Coat Colour/Pattern/Type
OMIA Url
Inheritance
A
Breed Specific Info
Researched Breeds
Afghan Hound
