This disorder occurs in many different forms, many of which are not inherited. Characterised by low platelet count, and problems with platelet production as well as premature destruction.
This disorder occurs in many different forms, many of which are not inherited. Characterised by low platelet count, and problems with platelet production as well as premature destruction. Rapid platelet consumption is often observed in acute haemorrhage, disseminated intravascular coagulation, or inflammation.
Davis, B., Toivio-Kinnucan, M., Schuller, S., Boudreaux, MK. : Mutation in beta1-tubulin correlates with macrothrombocytopenia in Cavalier King Charles Spaniels. J Vet Intern Med 22:540-5, 2008. Pubmed reference: 18466252. DOI: 10.1111/j.1939-1676.2008.0085.x.
Gelain,Bertazzolo, Tutino, Pogliani, Cian, Boudreaux: A novel point mutation in the ?1-tubulin gene in asymptomatic macrothrombocytopenic Norfolk and Cairn Terriers Veterinary Clinical Pathology 07/2014
Choosing a Genetic Test Provider Choosing a genetic test provider can be daunting. This short article helps you to consider what is important to you, and your dogs, in finding the right test provider for you.
The HGTD genetic counselling resources index link above and links below provide access to basic introductory articles on genetics, articles on application of genetics in breed health management and advanced work in technical genetics research. Breed-specific information is also available in DWN's Pedigreed Dogs Database.