Osteochondrodysplasia is an abnormality of the growth receptor genes, slowing development and growth of cartilage and bones, causing dwarfism and deformities in some cases throughout the body. Signs include: shortening of the long leg bones - normally all legs, but in some cases only 2-3 legs, severe pain, enlarged heads, arthritis and back problems. Other effects of this disease due to the retardation of bone and cartilage growth include: shortened muzzles or noses, bulging eyes, shorter jaws causing dentition issues, slow growth, inflammation of joints, retinal dysplasia. Age of onset from birth, but effects can seem progressive as they don't always fully manifest until maturity.