DonateProgressive Retinal Atrophy rcd3 (PRA-rcd3)
Breeds
Relevance Rating: There is some evidence or research available in this breed
Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful for these breeds
GTPs
General
Disease Name
Progressive Retinal Atrophy rcd3 (PRA-rcd3)
Mutation
c.1940delA
Details
PRA-rcd3 (Progressive Retinal Atrophy rod-cone degeneration 3) is an early-onset PRA mutation which causes progressive vision loss, and eventually blindness. Puppies may show signs of night-blindness by 6 weeks of age. By the age of 1-2 years most affected dogs are completely blind.
Details 2
PRA-rcd3 (Progressive Retinal Atrophy rod-cone degeneration 3) is an early-onset PRA mutation that causes bilateral degeneration of the retina which causes progressive vision loss, and eventually blindness. Puppies may show signs of night-blindness by 6 weeks of age. By the age of 1-2 years most affected dogs are completely blind.
Published
Petersen-Jones, S.M., Entz, D.D., Sargan, D.R. : CGMP phosphodiesterase-alpha mutation causes progressive retinal atrophy in the Cardigan Welsh corgi dog Investigative Ophthalmology & Visual Science 40:1637-1644, 1999. Pubmed reference: 10393029.
Breed Specific Info
Researched Breeds
Cardigan Welsh Corgi
