Shaking Puppy syndrome (SLEM)
Breed: Border Terrier
Generic Phene Data
Breeds
Relevance Rating: There is some evidence or research available in this breed
General
Disease Name
Shaking Puppy syndrome (SLEM)
OMIA
-41
Gene Name
unpublished
Mutation
unpublished
Test Type
Genetic Disease/Disorder
Details
Spongiform LeucoEncephaloMyelopathy (SLEM), sometimes referred to as Shaking puppy syndrome, affects the puppies from the time they begin to support weight and attempt to walk. Border Terriers affected by SLEM show severe tremors predominately in the hind limbs, this creates a side to side shaking. Collaborating scientists at the University of Missouri, the Animal Health Trust and at Wisdom Health, have identified a mutation responsible for this disease in the Border Terrier.
Published
No test/mutation publication information.
Body/System/Process
Neurologic
Inheritance
AR
Breed Specific Info
Researched Breeds
Border Terrier
Breed-specific 1
Border Terrier
HSP Test-Specific Data
Canine Genetic Testing
GTP
GTP Name
Canine Genetic Testing
Breed
OMIA
Gene Name
SLEM
Orthopedic Foundation for Animals
GTP
Breed
OMIA
Gene Name
SLC5A5