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Coat Colour, Extension
Breed: English Cocker Spaniel
Generic Phene Data
Breeds
Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful for these breeds
General
Disease Name
Coat Colour, Extension
OMIA
1199
Gene Name
MC1R
Mutation
c.916C>T
Mutation 2
p.R306*
Mutation 3
c.790A>G; g.233G>T
Test Type
Other Genetic Traits
Details
Testing for extension reveals whether a dog with a mask has one or two copies of this version of the extension locus. Dogs with a single copy can produce offspring with or without a mask, while those with two copies will only produce masked offspring.
Details 2
Testing for extension reveals whether a dog with a mask has one or two copies of this version of the extension locus. Dogs with a single copy can produce offspring with or without a mask, while those with two copies will only produce masked offspring.
Published
Newton, J.M., Wilkie, A.L., He, L., Jordan, S.A., Metallinos, D.L., Holmes, N.G., Jackson, I.J., Barsh, G.S. : Melanocortin 1 receptor variation in the domestic dog Mammalian Genome 11:24-30, 2000. Pubmed reference: 10602988.
Published 2
Everts, R.E., Rothuizen, J., van, Oost, B.A. : Identification of a premature stop codon in the melanocyte-stimulating hormone receptor gene (MC1R) in Labrador and Golden retrievers with yellow coat colour Animal Genetics 31:194-199, 2000. Pubmed reference: 10895310.
Published 3
Schmutz, S.M., Berryere, T.G., Goldfinch, A.D. : TYRP1 and MC1R genotypes and their effects on coat color in dogs Mammalian Genome 13:380-387, 2002. Pubmed reference: 12140685. DOI: 10.1007/s00335-001-2147-2.
Body/System/Process
Coat Colour/Pattern/Type
OMIA Url
Inheritance
A
HSP Test-Specific Data
Agrotis S.r.l.
GTP
GTP Name
Agrotis S.r.l.
Breed
OMIA
Gene Name
MC1R
Mutation
c.250G>A
BioBank AS
GTP
GTP Name
BioBank AS
Breed
OMIA
Gene Name
MC1R
Mutation
c.250G>A
Certagen GmbH
GTP
GTP Name
Certagen GmbH
Breed
OMIA
Gene Name
MC1R
Mutation
c.250G>A
CMSCH
GTP
GTP Name
CMSCH
Breed
OMIA
Gene Name
MC1R
Mutation
c.250G>A
Genomia s.r.o
GTP
GTP Name
Genomia s.r.o
Breed
OMIA
GTP Disease Synonym
LocEH
Gene Name
MC1R
Mutation
c.250G>A
Mutation Comment
g.63695000C>T
INNO
GTP
GTP Name
INNO
Breed
OMIA
Gene Name
MC1R
Mutation
c.250G>A
Laboratorios Labocor S.L.
GTP
GTP Name
Laboratorios Labocor S.L.
Breed
OMIA
Gene Name
MC1R
Mutation
c.250G>A
PharmaDNA
GTP
GTP Name
PharmaDNA
Breed
OMIA
Gene Name
MC1R
Mutation
c.250G>A
Independent Veterinary Laboratory POISK
GTP
GTP Name
Independent Veterinary Laboratory POISK
Breed
OMIA
GTP Disease Name
EM Locus
Gene Name
MC1R
Mutation
c.250G>A
Progènes-ADN
GTP
GTP Name
Progenes ADN
Breed
OMIA
Gene Name
MC1R
Mutation
c.250G>A
VHL Genetics
GTP
GTP Name
VHL Genetics
Breed
OMIA
Gene Name
MC1R
Mutation
c.250G>A
Zoolyx
GTP
GTP Name
Zoolyx
Breed
OMIA
Gene Name
MC1R
Mutation
c.250G>A
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Key Comment