Donate
Factor XI Deficiency
Breed: Jack Russell Terrier
Generic Phene Data
Breeds
Relevance Rating: There is some evidence or research available in this breed
Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful for these breeds
General
Disease Name
Factor XI Deficiency
OMIA
363
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7
Test Type
Genetic Disease/Disorder
Details
Blood coagulation problems noted in pregnant/ postpartum females. Some animals prolonged bleeding from injuries/surgeries.
Published
Tcherneva, E., Huff, A. M., Giger, U. : Coagulation factor XI deficiency in Kerry blue terrier dogs is caused by an exonic sine insertion Journal of Veterinary Internal Medicine 20:767 only, 2006.
Body/System/Process
Blood
OMIA Url
Inheritance
A
HSP Test-Specific Data
Agrotis S.r.l.
GTP
GTP Name
Agrotis S.r.l.
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
BioBank AS
GTP
GTP Name
BioBank AS
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Certagen GmbH
GTP
GTP Name
Certagen GmbH
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
CMSCH
GTP
GTP Name
CMSCH
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
DNA My Dog
GTP
GTP Name
DNA My Dog
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Nature of test
mutation test
GTP- or Breed-Specific Publications
Tcherneva, E., Huff, A. M., Giger, U. : Coagulation factor XI deficiency in Kerry blue terrier dogs is caused by an exonic sine insertion Journal of Veterinary Internal Medicine 20:767 only, 2006.
Application in the Breed
Carriers can be bred to normal animals (N/fIX x N/N) .Offspring should be tested before breeding. No breeding of two carriers (N/fIX x N/fIX). Blood coagulation problems noted in pregnant/ postpartum females. Some animals prolonged bleeding from injuries/surgeries.
Inheritance
AR
This test is outsourced to:
Orivet
FCI Number
345
GTP Breed
Jack Russell Terrier
INNO
GTP
GTP Name
INNO
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Laboratorios Labocor S.L.
GTP
GTP Name
Laboratorios Labocor S.L.
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Orivet Genetic Pet Care
GTP
GTP Name
Orivet Genetic Pet Care
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Nature of test
mutation test
GTP- or Breed-Specific Publications
Tcherneva, E., Huff, A. M., Giger, U. : Coagulation factor XI deficiency in Kerry blue terrier dogs is caused by an exonic sine insertion Journal of Veterinary Internal Medicine 20:767 only, 2006.
Application in the Breed
Carriers can be bred to normal animals (N/fIX x N/N) .Offspring should be tested before breeding. No breeding of two carriers (N/fIX x N/fIX). Blood coagulation problems noted in pregnant/ postpartum females. Some animals prolonged bleeding from injuries/surgeries.
Inheritance
AR
FCI Number
345
GTP Breed
Jack Russell Terrier
PharmaDNA
GTP
GTP Name
PharmaDNA
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Progènes-ADN
GTP
GTP Name
Progenes ADN
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
VHL Genetics
GTP
GTP Name
VHL Genetics
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Zoolyx
GTP
GTP Name
Zoolyx
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
-
HGTD Quick Search
-
The portal for Genetic Testing Providers (labs); genetic tests, and tests by breed: as well as information on quality indicators and genetic counseling resources.
GOAL: Robust genetic testing supporting health improvements & a sustainable future for healthy dogs. -
HGTD Database Resources
How to use the HGTD
Using HGTD - YouTube Videos
HGTD Quality Indicators
Acronyms - Mode of Inheritance♦ 2020-New What is a Relevance Rating?
FAQs
Answers to frequently asked questions about the HGTD
Accreditation Basics
This brief overview may help you identify what types of accreditation are important to you, when choosing your genetic test provider.
Accreditation and Industry Standards
List of organizations throughout the world that are involved in matters of accreditation and establishing industry standards.
Choosing a Genetic Test Provider
Choosing a genetic test provider can be daunting. This short article helps you to consider what is important to you, and your dogs, in finding the right test provider for you. -
The HGTD's genetic counselling resources index provides access to basic introductory articles on genetics, articles on application of genetics in breed health management, and advanced work in technical genetics research. Breed-specific information is also available in our Pedigreed Dogs Database.
