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Factor XI Deficiency
Breed: Kerry Blue Terrier
Generic Phene Data
Breeds
Relevance Rating: There is some evidence or research available in this breed
Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful for these breeds
General
Disease Name
Factor XI Deficiency
OMIA
363
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7
Test Type
Genetic Disease/Disorder
Details
Blood coagulation problems noted in pregnant/ postpartum females. Some animals prolonged bleeding from injuries/surgeries.
Published
Tcherneva, E., Huff, A. M., Giger, U. : Coagulation factor XI deficiency in Kerry blue terrier dogs is caused by an exonic sine insertion Journal of Veterinary Internal Medicine 20:767 only, 2006.
Body/System/Process
Blood
OMIA Url
Inheritance
A
HSP Test-Specific Data
VHL Genetics
GTP
GTP Name
VHL Genetics
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Zoolyx
GTP
GTP Name
Zoolyx
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Wisdom Panel - Kinship
GTP
GTP Name
Wisdom Panel - Kinship
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Nature of test
mutation test
GTP- or Breed-Specific Publications
Tcherneva, E., Huff, A. M., Giger, U. : Coagulation factor XI deficiency in Kerry blue terrier dogs is caused by an exonic sine insertion Journal of Veterinary Internal Medicine 20:767 only, 2006.
Application in the Breed
Carriers can be bred to normal animals (N/fIX x N/N) .Offspring should be tested before breeding. No breeding of two carriers (N/fIX x N/fIX). Blood coagulation problems noted in pregnant/ postpartum females. Some animals prolonged bleeding from injuries/surgeries.
Inheritance
AR
FCI Number
3
GTP Breed
Kerry Blue Terrier
CMSCH
GTP
GTP Name
CMSCH
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Progènes-ADN
GTP
GTP Name
Progenes ADN
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
PharmaDNA
GTP
GTP Name
PharmaDNA
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
INNO
GTP
GTP Name
INNO
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
VetGen LLC
GTP
GTP Name
VetGen LLC
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7
Agrotis S.r.l.
GTP
GTP Name
Agrotis S.r.l.
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
BioBank AS
GTP
GTP Name
BioBank AS
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
AnimaLabs
GTP
GTP Name
AnimaLabs
Breed
OMIA
Laboratorios Labocor S.L.
GTP
GTP Name
Laboratorios Labocor S.L.
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
Certagen GmbH
GTP
GTP Name
Certagen GmbH
Breed
OMIA
Gene Name
FXI
Mutation
ins90bpSine(polyA) in exon 7.
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