Donate
Hair, Long
Breed: Appenzell Cattle Dog
Generic Phene Data
Breeds
Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful for these breeds
General
Disease Name
Hair, Long
OMIA
439
Gene Name
FGF5
Gene Name 2
CanFam3.1, Chr. 32
Mutation
c.284G>T
Mutation 2
c.556_571del16
Mutation 3
c.559_560dupGG
Mutation 4
c.578C>T
Mutation 5
g.4509357G>T
Test Type
Other Genetic Traits
Details
Testing for a long coat can be useful for predicting possible breeding outcomes, which may be particularly useful for those concerned with coat length for meeting typical breed attributes.
Details 2
The long coat is caused by a recessive genetic mutation in the FGF5 gene.
Published
Housley, DJ., Venta, PJ. : The long and the short of it: evidence that FGF5 is a major determinant of canine 'hair'-itability. Anim Genet 37:309-15, 2006. Pubmed reference: 16879338. DOI: 10.1111/j.1365-2052.2006.01448.x.
Published 2
Cadieu, E., Neff, M.W., Quignon, P., Walsh, K., Chase, K., Parker, H.G., Vonholdt, B.M., Rhue, A., Boyko, A., Byers, A., Wong, A., Mosher, D.S., Elkahloun, A.G., Spady, T.C., André, C., Lark, K.G., Cargill, M., Bustamante, C.D., Wayne, R.K., Ostrander, E.A. : Coat variation in the domestic dog is governed by variants in three genes. Science 326:150-3, 2009. Pubmed reference: 19713490. DOI: 10.1126/science.1177808.
Published 3
Dierks, C., Mömke, S., Philipp, U., Distl, O. : Allelic heterogeneity of FGF5 mutations causes the long-hair phenotype in dogs. Anim Genet 44:425-31, 2013. Pubmed reference: 23384345. DOI: 10.1111/age.12010.
Published 4
Parker, H.G., Harris, A., Dreger, D.L., Davis, B.W., Ostrander, E.A. : The bald and the beautiful: hairlessness in domestic dog breeds. Philos Trans R Soc Lond B Biol Sci 372:, 2017. Pubmed reference: 27994129. DOI: 10.1098/rstb.2015.0488.
Body/System/Process
Coat Colour/Pattern/Type
OMIA Url
Inheritance
AR
HSP Test-Specific Data
Agrotis S.r.l.
GTP
GTP Name
Agrotis S.r.l.
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
BioBank AS
GTP
GTP Name
BioBank AS
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
Certagen GmbH
GTP
GTP Name
Certagen GmbH
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
CMSCH
GTP
GTP Name
CMSCH
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
EVG Diagnostics
GTP
GTP Name
EVG Molecular Diagnostics
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T
Genomia s.r.o
GTP
GTP Name
Genomia s.r.o
Breed
OMIA
GTP Disease Name
L Locus (Long Hair/Fluffy)
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16; c.559_560dupGG; c.578C>T
Nature of test
mutation test
INNO
GTP
GTP Name
INNO
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
Laboratorios Labocor S.L.
GTP
GTP Name
Laboratorios Labocor S.L.
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
PharmaDNA
GTP
GTP Name
PharmaDNA
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
Independent Veterinary Laboratory POISK
GTP
GTP Name
Independent Veterinary Laboratory POISK
Breed
OMIA
GTP Disease Name
L Locus (Long Hair/Fluffy)
Gene Name
FGF5
Mutation
c.284G>T
Progènes-ADN
GTP
GTP Name
Progenes ADN
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
VHL Genetics
GTP
GTP Name
VHL Genetics
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
Zoolyx
GTP
GTP Name
Zoolyx
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
AnimaLabs
GTP
GTP Name
AnimaLabs
Breed
OMIA
-
HGTD Quick Search
-
The portal for Genetic Testing Providers (labs); genetic tests, and tests by breed: as well as information on quality indicators and genetic counseling resources.
GOAL: Robust genetic testing supporting health improvements & a sustainable future for healthy dogs. -
HGTD Database Resources
How to use the HGTD
Using HGTD - YouTube Videos
HGTD Quality Indicators
Acronyms - Mode of Inheritance♦ 2020-New What is a Relevance Rating?
FAQs
Answers to frequently asked questions about the HGTD
Accreditation Basics
This brief overview may help you identify what types of accreditation are important to you, when choosing your genetic test provider.
Accreditation and Industry Standards
List of organizations throughout the world that are involved in matters of accreditation and establishing industry standards.
Choosing a Genetic Test Provider
Choosing a genetic test provider can be daunting. This short article helps you to consider what is important to you, and your dogs, in finding the right test provider for you. -
The HGTD's genetic counselling resources index provides access to basic introductory articles on genetics, articles on application of genetics in breed health management, and advanced work in technical genetics research. Breed-specific information is also available in our Pedigreed Dogs Database.
Key Comment