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Hair, Long
Breed: Alaskan Malamute
Generic Phene Data
Breeds
Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful for these breeds
General
Disease Name
Hair, Long
OMIA
439
Gene Name
FGF5
Gene Name 2
CanFam3.1, Chr. 32
Mutation
c.284G>T
Mutation 2
c.556_571del16
Mutation 3
c.559_560dupGG
Mutation 4
c.578C>T
Mutation 5
g.4509357G>T
Test Type
Other Genetic Traits
Details
Testing for a long coat can be useful for predicting possible breeding outcomes, which may be particularly useful for those concerned with coat length for meeting typical breed attributes.
Details 2
The long coat is caused by a recessive genetic mutation in the FGF5 gene.
Published
Housley, DJ., Venta, PJ. : The long and the short of it: evidence that FGF5 is a major determinant of canine 'hair'-itability. Anim Genet 37:309-15, 2006. Pubmed reference: 16879338. DOI: 10.1111/j.1365-2052.2006.01448.x.
Published 2
Cadieu, E., Neff, M.W., Quignon, P., Walsh, K., Chase, K., Parker, H.G., Vonholdt, B.M., Rhue, A., Boyko, A., Byers, A., Wong, A., Mosher, D.S., Elkahloun, A.G., Spady, T.C., André, C., Lark, K.G., Cargill, M., Bustamante, C.D., Wayne, R.K., Ostrander, E.A. : Coat variation in the domestic dog is governed by variants in three genes. Science 326:150-3, 2009. Pubmed reference: 19713490. DOI: 10.1126/science.1177808.
Published 3
Dierks, C., Mömke, S., Philipp, U., Distl, O. : Allelic heterogeneity of FGF5 mutations causes the long-hair phenotype in dogs. Anim Genet 44:425-31, 2013. Pubmed reference: 23384345. DOI: 10.1111/age.12010.
Published 4
Parker, H.G., Harris, A., Dreger, D.L., Davis, B.W., Ostrander, E.A. : The bald and the beautiful: hairlessness in domestic dog breeds. Philos Trans R Soc Lond B Biol Sci 372:, 2017. Pubmed reference: 27994129. DOI: 10.1098/rstb.2015.0488.
Body/System/Process
Coat Colour/Pattern/Type
OMIA Url
Inheritance
AR
HSP Test-Specific Data
Genomia s.r.o
GTP
GTP Name
Genomia s.r.o
Breed
OMIA
GTP Disease Name
L Locus (Long Hair/Fluffy)
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16; c.559_560dupGG; c.578C>T
Nature of test
mutation test
EVG Diagnostics
GTP
GTP Name
EVG Molecular Diagnostics
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T
Independent Veterinary Laboratory POISK
GTP
GTP Name
Independent Veterinary Laboratory POISK
Breed
OMIA
GTP Disease Name
L Locus (Long Hair/Fluffy)
Gene Name
FGF5
Mutation
c.284G>T
Agrotis S.r.l.
GTP
GTP Name
Agrotis S.r.l.
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
BioBank AS
GTP
GTP Name
BioBank AS
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
Laboratorios Labocor S.L.
GTP
GTP Name
Laboratorios Labocor S.L.
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
Certagen GmbH
GTP
GTP Name
Certagen GmbH
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
VHL Genetics
GTP
GTP Name
VHL Genetics
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
Zoolyx
GTP
GTP Name
Zoolyx
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
CMSCH
GTP
GTP Name
CMSCH
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
Progènes-ADN
GTP
GTP Name
Progenes ADN
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
PharmaDNA
GTP
GTP Name
PharmaDNA
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
AnimaLabs
GTP
GTP Name
AnimaLabs
Breed
OMIA
INNO
GTP
GTP Name
INNO
Breed
OMIA
Gene Name
FGF5
Mutation
c.284G>T; c.556_571del16
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