Improper Coat/Furnishings
Breeds
Relevance Rating: There is some evidence or research available in this breed
Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful for these breeds
General
Disease Name
Improper Coat/Furnishings
OMIA
1498
Gene Name
RSPO2
Mutation
167 bp 3' UTR insertion
Test Type
Other Genetic Traits
Details
The IC Locus determines for some breeds the variation in the dog's coat that makes its texture and appearance look different from the breed standard - i.e. change in hair type from wired to straight. It can also influence the presense or absense of "furnishings" (mustache and eyebrows). For some breeds and crosses, having the Improper Coat (IC) variation appears to be associated with dogs prone to shedding. Inherited phenotypes include: furnishings + proper coat, furnishings + improper coat, no furnishings + improper coat. The overall coat type is dependent on the combination of this dog's genotypes at the L, Cu, and IC loci.
Details 2
The IC Locus determines for some breeds the variation in the dog's coat that makes its texture and appearance look different from the breed standard - i.e. change in hair type from wired to straight. It can also influence the presense or absense of "furnishings" (mustache and eyebrows). For some breeds and crosses, having the Improper Coat (IC) variation appears to be associated with dogs prone to shedding. Inherited phenotypes include: furnishings + proper coat, furnishings + improper coat, no furnishings + improper coat. The overall coat type is dependent on the combination of this dog's genotypes at the L, Cu, and IC loci.
Published
Parker, HG., Chase, K., Cadieu, E., Lark, KG., Ostrander, EA. : An insertion in the RSPO2 gene correlates with improper coat in the Portuguese water dog. J Hered 101:612-7, 2010. Pubmed reference: 20562213. DOI: 10.1093/jhered/esq068.
Published 2
Parker, H.G., Harris, A., Dreger, D.L., Davis, B.W., Ostrander, E.A. : The bald and the beautiful: hairlessness in domestic dog breeds. Philos Trans R Soc Lond B Biol Sci 372:, 2017. Pubmed reference: 27994129. DOI: 10.1098/rstb.2015.0488.
Body/System/Process
Coat Colour/Pattern/Type
OMIA Url
Inheritance
A
Breed Specific Info
Researched Breeds
Portugese Water Dog