Improper Coat/Furnishings
            Breed: Havanese
        
        
        
        
    Generic Phene Data
        
            Breeds
        
    
    
                
                Relevance Rating: There is some evidence or research available  in this breed 
                
            
            
            
                
                Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful  for these breeds 
                
                
                
            
            
        
        General
        
            Disease Name
        
    
    
            Improper Coat/Furnishings
            
        
        
        
            OMIA
        
    
    
            1498
            
        
        
        
            Gene Name
        
    
    
            RSPO2
            
        
        
        
            Mutation
        
    
    
            167 bp 3' UTR insertion
            
        
        
        
            Test Type
        
    
    
            Other Genetic Traits
            
        
        
        
            Details
        
    
    
            The IC Locus determines for some breeds the variation in the dog's coat that makes its texture and appearance look different from the breed standard - i.e. change in hair type from wired to straight. It can also influence the presense or absense of "furnishings" (mustache and eyebrows). For some breeds and crosses, having the Improper Coat (IC) variation appears to be associated with dogs prone to shedding. Inherited phenotypes include: furnishings + proper coat, furnishings + improper coat, no furnishings + improper coat. The overall coat type is dependent on the combination of this dog's genotypes at the L, Cu, and IC loci.
            
        
        
        
            Details 2
        
    
    
            The IC Locus determines for some breeds the variation in the dog's coat that makes its texture and appearance look different from the breed standard - i.e. change in hair type from wired to straight. It can also influence the presense or absense of "furnishings" (mustache and eyebrows). For some breeds and crosses, having the Improper Coat (IC) variation appears to be associated with dogs prone to shedding. Inherited phenotypes include: furnishings + proper coat, furnishings + improper coat, no furnishings + improper coat. The overall coat type is dependent on the combination of this dog's genotypes at the L, Cu, and IC loci.
            
        
        
        
            Published
        
    
    
            Parker, HG., Chase, K., Cadieu, E., Lark, KG., Ostrander, EA. : An insertion in the RSPO2 gene correlates with improper coat in the Portuguese water dog. J Hered 101:612-7, 2010. Pubmed reference: 20562213. DOI: 10.1093/jhered/esq068.
            
        
        
        
            Published 2
        
    
    
            Parker, H.G., Harris, A., Dreger, D.L., Davis, B.W., Ostrander, E.A. : The bald and the beautiful: hairlessness in domestic dog breeds. Philos Trans R Soc Lond B Biol Sci 372:, 2017. Pubmed reference: 27994129. DOI: 10.1098/rstb.2015.0488.
            
        
        
        
            Body/System/Process
        
    
    
            Coat Colour/Pattern/Type
            
        
        
        
            OMIA Url
        
    
    
        
            Inheritance
        
    
    
            A
            
        
        Breed Specific Info
        
            Researched Breeds
        
    
    
            Portugese Water Dog
            
        
        HSP Test-Specific Data
Agrotis S.r.l.
        
            GTP
        
    
    
        
            GTP Name
        
    
    
            Agrotis S.r.l.
            
        
        
        
            Breed
        
    
    
        
            OMIA
        
    
    
        
            Gene Name
        
    
    
            RSPO2
            
        
        
        
            Mutation
        
    
    
            167 bp insertion in 3'UTR region
            
        
        BioBank AS
        
            GTP
        
    
    
        
            GTP Name
        
    
    
            BioBank AS
            
        
        
        
            Breed
        
    
    
        
            OMIA
        
    
    
        
            Gene Name
        
    
    
            RSPO2
            
        
        
        
            Mutation
        
    
    
            167 bp insertion in 3'UTR region
            
        
        Certagen GmbH
        
            GTP
        
    
    
        
            GTP Name
        
    
    
            Certagen GmbH
            
        
        
        
            Breed
        
    
    
        
            OMIA
        
    
    
        
            Gene Name
        
    
    
            RSPO2
            
        
        
        
            Mutation
        
    
    
            167 bp insertion in 3'UTR region
            
        
        CMSCH
        
            GTP
        
    
    
        
            GTP Name
        
    
    
            CMSCH
            
        
        
        
            Breed
        
    
    
        
            OMIA
        
    
    
        
            Gene Name
        
    
    
            RSPO2
            
        
        
        
            Mutation
        
    
    
            167 bp insertion in 3'UTR region
            
        
        Genomia s.r.o
        
            GTP
        
    
    
        
            GTP Name
        
    
    
            Genomia s.r.o
            
        
        
        
            Breed
        
    
    
        
            OMIA
        
    
    
        
            GTP Disease Name
        
    
    
            Improper coat
            
        
        
        
            GTP Disease Synonym
        
    
    
            Furnishings
            
        
        
        
            Gene Name
        
    
    
            RSPO2
            
        
        
        
            Mutation
        
    
    
            167 bp insertion in 3'UTR region
            
        
        
        
            Nature of test
        
    
    
            mutation test
            
        
        
        
            FCI Number
        
    
    
            250
            
        
        
        
            GTP Breed
        
    
    
            Havanese
            
        
        INNO
        
            GTP
        
    
    
        
            GTP Name
        
    
    
            INNO
            
        
        
        
            Breed
        
    
    
        
            OMIA
        
    
    
        
            Gene Name
        
    
    
            RSPO2
            
        
        
        
            Mutation
        
    
    
            167 bp insertion in 3'UTR region
            
        
        Laboratorios Labocor S.L.
        
            GTP
        
    
    
        
            GTP Name
        
    
    
            Laboratorios Labocor S.L.
            
        
        
        
            Breed
        
    
    
        
            OMIA
        
    
    
        
            Gene Name
        
    
    
            RSPO2
            
        
        
        
            Mutation
        
    
    
            167 bp insertion in 3'UTR region
            
        
        PharmaDNA
        
            GTP
        
    
    
        
            GTP Name
        
    
    
            PharmaDNA
            
        
        
        
            Breed
        
    
    
        
            OMIA
        
    
    
        
            Gene Name
        
    
    
            RSPO2
            
        
        
        
            Mutation
        
    
    
            167 bp insertion in 3'UTR region
            
        
        Progènes-ADN
        
            GTP
        
    
    
        
            GTP Name
        
    
    
            Progenes ADN
            
        
        
        
            Breed
        
    
    
        
            OMIA
        
    
    
        
            Gene Name
        
    
    
            RSPO2
            
        
        
        
            Mutation
        
    
    
            167 bp insertion in 3'UTR region
            
        
        VHL Genetics/ Combibreed
        
            GTP
        
    
    
        
            GTP Name
        
    
    
            VHL Genetics
            
        
        
        
            Breed
        
    
    
        
            OMIA
        
    
    
        
            Gene Name
        
    
    
            RSPO2
            
        
        
        
            Mutation
        
    
    
            167 bp insertion in 3'UTR region
            
        
        Zoolyx
        
            GTP
        
    
    
        
            GTP Name
        
    
    
            Zoolyx
            
        
        
        
            Breed
        
    
    
        
            OMIA
        
    
    
        
            Gene Name
        
    
    
            RSPO2
            
        
        
        
            Mutation
        
    
    
            167 bp insertion in 3'UTR region
            
        
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