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Curly Coat
Breeds
Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful in this breed
GTPs
General
Disease Name
Curly Coat
OMIA
245
Gene Name
KRT71
Mutation
c.451C>T
Test Type
Other Genetic Traits
Details
This influences the texture of the dog coat and hair formation. Inheritance (or "options" for coat type) is related to breed. The allele CC is dominant, and results in a curly coat. Only when the dog has two copies of the recessive allele is the coat is of a non-curly type. Some breeds are fixed (only ever curly-coated) for the dominant allele CC. Other breeds can have either curly or non-curly hair. Not to be confused with "curly coat/dry eye" which is a disease.
Published
Cadieu, E., Neff, M.W., Quignon, P., Walsh, K., Chase, K., Parker, H.G., Vonholdt, B.M., Rhue, A., Boyko, A., Byers, A., Wong, A., Mosher, D.S., Elkahloun, A.G., Spady, T.C., André, C., Lark, K.G., Cargill, M., Bustamante, C.D., Wayne, R.K., Ostrander, E.A. : Coat variation in the domestic dog is governed by variants in three genes. Science 326:150-3, 2009. Pubmed reference: 19713490. DOI: 10.1126/science.1177808.
Published 2
Parker, H.G., Harris, A., Dreger, D.L., Davis, B.W., Ostrander, E.A. : The bald and the beautiful: hairlessness in domestic dog breeds. Philos Trans R Soc Lond B Biol Sci 372:, 2017. Pubmed reference: 27994129. DOI: 10.1098/rstb.2015.0488.
Published 3
Harel, S., Christiano, A.M. : Keratin 71 mutations: from water dogs to woolly hair. J Invest Dermatol 132:2315-7, 2012. Pubmed reference: 22971920. DOI: 10.1038/jid.2012.291.
Body/System/Process
Coat Colour/Pattern/Type
OMIA Url
Inheritance
A
