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Curly Coat
Breed: ALL
Generic Phene Data
Breeds
Relevance Rating: The test is unknown, there is no evidence (i.e. research) available, or it has not been evaluated yet. These tests may or may not be meaningful in this breed
General
Disease Name
Curly Coat
OMIA
245
Gene Name
KRT71
Mutation
c.451C>T
Test Type
Other Genetic Traits
Details
This influences the texture of the dog coat and hair formation. Inheritance (or "options" for coat type) is related to breed. The allele CC is dominant, and results in a curly coat. Only when the dog has two copies of the recessive allele is the coat is of a non-curly type. Some breeds are fixed (only ever curly-coated) for the dominant allele CC. Other breeds can have either curly or non-curly hair. Not to be confused with "curly coat/dry eye" which is a disease.
Published
Cadieu, E., Neff, M.W., Quignon, P., Walsh, K., Chase, K., Parker, H.G., Vonholdt, B.M., Rhue, A., Boyko, A., Byers, A., Wong, A., Mosher, D.S., Elkahloun, A.G., Spady, T.C., André, C., Lark, K.G., Cargill, M., Bustamante, C.D., Wayne, R.K., Ostrander, E.A. : Coat variation in the domestic dog is governed by variants in three genes. Science 326:150-3, 2009. Pubmed reference: 19713490. DOI: 10.1126/science.1177808.
Published 2
Parker, H.G., Harris, A., Dreger, D.L., Davis, B.W., Ostrander, E.A. : The bald and the beautiful: hairlessness in domestic dog breeds. Philos Trans R Soc Lond B Biol Sci 372:, 2017. Pubmed reference: 27994129. DOI: 10.1098/rstb.2015.0488.
Published 3
Harel, S., Christiano, A.M. : Keratin 71 mutations: from water dogs to woolly hair. J Invest Dermatol 132:2315-7, 2012. Pubmed reference: 22971920. DOI: 10.1038/jid.2012.291.
Body/System/Process
Coat Colour/Pattern/Type
OMIA Url
Inheritance
A
HSP Test-Specific Data
INNO
GTP
GTP Name
INNO
Breed
OMIA
Gene Name
KRT71
Mutation
c.451C>T
Veterinary Genetics Laboratory
GTP
GTP Name
Veterinary Genetics Laboratory
Breed
OMIA
GTP Disease Name
Cu Locus (Curly Hair)
Gene Name
KRT71
Mutation
c.451C>T
Nature of test
mutation test
GTP- or Breed-Specific Publications
Cadieu E, Neff MW, Quignon P, Walsh K, Chase K, Parker HG, Vonholdt BM, Rhue A, Boyko A, Byers A, Wong A, Mosher DS, Elkahloun AG, Spady TC, Andr?? C, Lark KG, Cargill M, Bustamante CD, Wayne RK, Ostrander EA. Coat variation in the domestic dog is governed
FCI Number
-20
GTP Breed
ALL
GenSol Diagnostics
GTP
GTP Name
GenSol Diagnostics
Breed
OMIA
GTP Disease Name
Cu Locus (Curly Hair)
Gene Name
KRT71
Mutation
c.451C>T
GTP- or Breed-Specific Publications
Cadieu E, Neff MW, Quignon P, Walsh K, Chase K, Parker HG, Vonholdt BM, Rhue A, Boyko A, Byers A, Wong A, Mosher DS, Elkahloun AG, Spady TC, Andr?? C, Lark KG, Cargill M, Bustamante CD, Wayne RK, Ostrander EA. Coat variation in the domestic dog is governed
Paw Print Genetics
GTP
GTP Name
Paw Print Genetics
Breed
OMIA
GTP Disease Name
Cu Locus (Curly Hair)
Gene Name
KRT71
Mutation
c.451C>T
Nature of test
mutation test
FCI Number
-20
Agrotis S.r.l.
GTP
GTP Name
Agrotis S.r.l.
Breed
OMIA
Gene Name
KRT71
Mutation
c.451C>T
BioBank AS
GTP
GTP Name
BioBank AS
Breed
OMIA
Gene Name
KRT71
Mutation
c.451C>T
Laboratorios Labocor S.L.
GTP
GTP Name
Laboratorios Labocor S.L.
Breed
OMIA
Gene Name
KRT71
Mutation
c.451C>T
Certagen GmbH
GTP
GTP Name
Certagen GmbH
Breed
OMIA
Gene Name
KRT71
Mutation
c.451C>T
Generatio GmbH Center for Animal Genetics
GTP
GTP Name
Generatio GmbH Center for Animal Genetics
Breed
OMIA
GTP Disease Name
Cu Locus (Curly Hair)
Gene Name
KRT71
Mutation
c.451C>T
VHL Genetics
GTP
GTP Name
VHL Genetics
Breed
OMIA
Gene Name
KRT71
Mutation
c.451C>T
Zoolyx
GTP
GTP Name
Zoolyx
Breed
OMIA
Gene Name
KRT71
Mutation
c.451C>T
Wisdom Panel - Kinship
GTP
GTP Name
Wisdom Panel - Kinship
Breed
OMIA
GTP Disease Name
Cu Locus (Curly Hair)
Gene Name
KRT71
Mutation
c.451C>T
Nature of test
mutation test
FCI Number
-20
GTP Breed
ALL
AnimaLabs
GTP
GTP Name
AnimaLabs
Breed
OMIA
Laboklin Gmbh & Co. KG
GTP
GTP Name
Laboklin Gmbh & Co. KG
Breed
OMIA
GTP Disease Name
Cu Locus (Curly Hair)
Gene Name
KRT71
Mutation
c.451C>T
Nature of test
mutation test
FCI Number
-20
CMSCH
GTP
GTP Name
CMSCH
Breed
OMIA
Gene Name
KRT71
Mutation
c.451C>T
Progènes-ADN
GTP
GTP Name
Progenes ADN
Breed
OMIA
Gene Name
KRT71
Mutation
c.451C>T
PharmaDNA
GTP
GTP Name
PharmaDNA
Breed
OMIA
Gene Name
KRT71
Mutation
c.451C>T
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