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Degenerative Myelopathy
Breeds
HSP's
Condition
Degenerative Myelopathy
Synonym
DM,Degenerative Myelopathie,Myélopathie dégénérative,Degenerativ myelopati,Degeneratiivinen myelopatia,Degeneratieve Myelopathie
Condition Description
DM is an incompletely penetrant autosomal recessive disease, usually affecting dogs 5 years of age or older. The mutation tested for in most breeds is the SOD1:c.118A, referred to as SOD1-A or exon 2. In the Bernese Mountain Dog breed two direct DNA tests
Specific Condition(s)
Degenerative Myelopathy
Test Types(s)
genetic/genomic; necropsy
Specific test/ grading system 1
Can only be definitively diagnosed by post-mortem examination of the spine
Type
Disease/ disorder
System
Neurological
Anatomic Location
spine