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Degenerative Myelopathy
Breed: Bernese Mountain Dog
Breeds in this Condition
Breeds
Condition
Degenerative Myelopathy
Synonym
DM,Degenerative Myelopathie,Myélopathie dégénérative,Degenerativ myelopati,Degeneratiivinen myelopatia,Degeneratieve Myelopathie
Condition Description
DM is an incompletely penetrant autosomal recessive disease, usually affecting dogs 5 years of age or older. The mutation tested for in most breeds is the SOD1:c.118A, referred to as SOD1-A or exon 2. In the Bernese Mountain Dog breed two direct DNA tests
Specific Condition(s)
Degenerative Myelopathy
Test Types(s)
genetic/genomic; necropsy
Specific test/ grading system 1
Can only be definitively diagnosed by post-mortem examination of the spine
Type
Disease/ disorder
System
Neurological
Anatomic Location
spine
HSP Test-Specific Data
Bernese Mountain Dog Club of Great Britain
HSP
HSP Name 2
BMDCGB
Breed
Condition
Specific Condition[s]
DM; genes: SOD1; SOD1-B
Breed-specific Condition Descripton
Specific test type(s)
genetic/genomic
Recommended Comment
See the RASfor particulars.
See the Get a GRIHP! on Bernese Mountain Dogs(2021) for more information.
Recognized
Date
02/03/2023 07:37 PM
Country
United Kingdom
Country code
UK
Sennenhund Breeds Club (Finland)
HSP
HSP Name 2
Suomen Sveitsinpaimenkoirat ry
Breed
Condition
Specific Condition[s]
DM; genes: SOD1; SOD1-B
Breed-specific Condition Descripton
Degenerative Radiculomyelopathy
Specific test type(s)
genetic/genomic
Required Comment
-
Recommended
Recommended Comment
-
Recognized Comment
-
Date
02/03/2023 07:37 PM
Country
Finland
Country code
FI
Additional Information
Bernese Mountain Dog Club of America
HSP
Breed
Condition
Breed-specific Condition Descripton
2 mutations - SOD1A (Exon 2) and SOD1B (Exon 1)
See: http://www.bmdinfo.org/Health/Degenerative_Myelopathy_Bernese_Mountain_Dog.php
Recommended
Date
03/25/2023 07:00 AM
Country
United States
Country code
US