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Degenerative Myelopathy
Breed: German Shepherd Dog/ Double coat
Breeds in this Condition
Breeds
Condition
Degenerative Myelopathy
Synonym
DM,Degenerative Myelopathie,Myélopathie dégénérative,Degenerativ myelopati,Degeneratiivinen myelopatia,Degeneratieve Myelopathie
Condition Description
DM is an incompletely penetrant autosomal recessive disease, usually affecting dogs 5 years of age or older. The mutation tested for in most breeds is the SOD1:c.118A, referred to as SOD1-A or exon 2. In the Bernese Mountain Dog breed two direct DNA tests
Specific Condition(s)
Degenerative Myelopathy
Test Types(s)
genetic/genomic; necropsy
Specific test/ grading system 1
Can only be definitively diagnosed by post-mortem examination of the spine
Type
Disease/ disorder
System
Neurological
Anatomic Location
spine
HSP Test-Specific Data
The Kennel Club
HSP
HSP Name 2
The Kennel Club
Breed
Condition
Specific Condition[s]
DM; genes: SOD1; SOD1-B
Breed-specific Condition Descripton
Degenerative Myelopathy (DM) see: HGTD Phene/test search: https://dogwellnet.com/ctp/
Specific test type(s)
genetic/genomic
Required by HSP
Required Comment
For Assured Breeders: DNA tests - there are various official DNA testing schemes depending on the condition concerned. Where a DNA test is a requirement for a breed, both parents must have either been tested, or have proven hereditary clear status, with at least one parent being clear of the relevant condition.
Date
02/03/2023 07:37 PM
Country
United Kingdom
Country code
UK
Additional Information
German Shepherd Dog Breed Association (Finland)
HSP
HSP Name 2
Saksanpaimenkoiraliitto ry
Breed
Condition
Specific Condition[s]
DM; genes: SOD1; SOD1-B
Breed-specific Condition Descripton
Degenerative Myelopathy;
Specific test type(s)
genetic/genomic;
Required Comment
-
Recommended
Recommended Comment
-
Recognized Comment
-
Date
02/03/2023 07:37 PM
Country
Finland
Country code
FI
Additional Information