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Degenerative Myelopathy
Breed: Welsh Corgi Pembroke
Breeds in this Condition
Breeds
Condition
Degenerative Myelopathy
Synonym
DM,Degenerative Myelopathie,Myélopathie dégénérative,Degenerativ myelopati,Degeneratiivinen myelopatia,Degeneratieve Myelopathie
Condition Description
DM is an incompletely penetrant autosomal recessive disease, usually affecting dogs 5 years of age or older. The mutation tested for in most breeds is the SOD1:c.118A, referred to as SOD1-A or exon 2. In the Bernese Mountain Dog breed two direct DNA tests
Specific Condition(s)
Degenerative Myelopathy
Test Types(s)
genetic/genomic; necropsy
Specific test/ grading system 1
Can only be definitively diagnosed by post-mortem examination of the spine
Type
Disease/ disorder
System
Neurological
Anatomic Location
spine
HSP Test-Specific Data
Finnish Welsh Corgi Society
HSP
HSP Name 2
Suomen Welsh Corgi Seura - Finska Welsh Corgi Sällskapet ry
Breed
Condition
Specific Condition[s]
DM; genes: SOD1; SOD1-B
Specific test type(s)
genetic/genomic
Required Comment
-
Recommended Comment
-
Recognized
Recognized Comment
-
Date
02/03/2023 07:37 PM
Country
Finland
Country code
FI
Additional Information
Pembroke Welsh Corgi Club of America
HSP
HSP Name 2
Pembroke Welsh Corgi Club of America
Breed
Condition
Specific Condition[s]
DM; genes: SOD1; SOD1-B
Breed-specific Condition Descripton
See:
Canine Degenerative Myelopathy and Genetic Testing in Pembroke Welsh Corgis
Dr Jerold S Bell is an adjunct Professor of clinical genetics at the Cummings School of Veterinary Medicine, Tufts University. He prepared this explanation of Canine Degenerative Myelopathy in the Pembroke Welsh Corgi to help breeders/owners of Pembrokes better understand the clinical and genetic complexities of this much misunderstood condition.
For the full article, please click here - https://pembrokecorgi.org/about-pembrokes/canine-degenerative-myelopathy-and-genetic-testing-in-pwcs
Specific test type(s)
genetic/genomic
Recognized
Recognized Comment
Date
02/03/2023 07:37 PM
Country
United States
Country code
US
Additional Information